ES461837A1 - Procedimiento para la preparacion de derivados de prostano. - Google Patents

Procedimiento para la preparacion de derivados de prostano.

Info

Publication number
ES461837A1
ES461837A1 ES461837A ES461837A ES461837A1 ES 461837 A1 ES461837 A1 ES 461837A1 ES 461837 A ES461837 A ES 461837A ES 461837 A ES461837 A ES 461837A ES 461837 A1 ES461837 A1 ES 461837A1
Authority
ES
Spain
Prior art keywords
radical
derivatives
prostane derivatives
alkyl
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES461837A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES461837A1 publication Critical patent/ES461837A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Procedimiento para la preparación de derivados de fórmula general: (Fórmula I) En la que R1 es un radical hidroximetilo, n es 1 o 2, X es un radical etileno o trans-vinileno, Y es un enlace directo, un radical alquilenoxi C1-5 en el que el átomo de oxígeno está enlazado a R2, o un radical alquileno C1-5, y R2 es un radical fenilo opcionalmente sustituido por átomos de halógeno o radicales alquilo C1-5, alcoxi o halógeno-alquilo.
ES461837A 1975-08-22 1977-08-23 Procedimiento para la preparacion de derivados de prostano. Expired ES461837A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB34969/75A GB1516414A (en) 1975-08-22 1975-08-22 Prostane derivatives

Publications (1)

Publication Number Publication Date
ES461837A1 true ES461837A1 (es) 1978-05-16

Family

ID=10372250

Family Applications (2)

Application Number Title Priority Date Filing Date
ES450866A Expired ES450866A1 (es) 1975-08-22 1976-08-20 Procedimiento para la preparacion de derivados de prostano.
ES461837A Expired ES461837A1 (es) 1975-08-22 1977-08-23 Procedimiento para la preparacion de derivados de prostano.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES450866A Expired ES450866A1 (es) 1975-08-22 1976-08-20 Procedimiento para la preparacion de derivados de prostano.

Country Status (21)

Country Link
US (2) US4241215A (es)
JP (1) JPS5225746A (es)
AR (1) AR211276A1 (es)
AT (1) AT353431B (es)
AU (1) AU510107B2 (es)
BE (1) BE845404A (es)
CA (1) CA1088932A (es)
DD (1) DD125481A5 (es)
DE (1) DE2637384A1 (es)
DK (1) DK372376A (es)
ES (2) ES450866A1 (es)
FI (1) FI762386A7 (es)
FR (1) FR2322587A1 (es)
GB (1) GB1516414A (es)
IE (1) IE43930B1 (es)
IL (1) IL50213A0 (es)
IN (1) IN144651B (es)
NL (1) NL7609223A (es)
NO (1) NO762708L (es)
SE (1) SE424860B (es)
ZA (1) ZA764646B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582853A (en) * 1977-06-16 1981-01-14 Ici Ltd Prostane derivatives
FR2399999A1 (fr) * 1977-08-12 1979-03-09 Ici Ltd Carbamates ou esters de derives du 4-prostene-1-ol et composition pharmaceutique ou veterinaire les contenant
JPS5686083A (en) * 1979-12-13 1981-07-13 Trio Kenwood Corp Controlling device for motor
JPS59148588A (ja) * 1983-02-10 1984-08-25 Fuji Photo Film Co Ltd 電動機の速度制御装置
CN1237157A (zh) 1996-11-12 1999-12-01 阿尔康实验室公司 作为眼压降低剂的前列腺素的顺式－△4类似物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2317019A1 (de) * 1972-04-27 1973-11-08 Upjohn Co Neue 4,5-didehydro-prostaglandine
DD118856A5 (es) * 1972-11-08 1976-03-20
US4032561A (en) * 1975-05-27 1977-06-28 The Upjohn Company 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF1.sub.α compounds

Also Published As

Publication number Publication date
IN144651B (es) 1978-06-03
IL50213A0 (en) 1976-10-31
FR2322587A1 (fr) 1977-04-01
FR2322587B1 (es) 1980-03-28
DE2637384A1 (de) 1977-03-03
DK372376A (da) 1977-02-23
ZA764646B (en) 1977-07-27
DD125481A5 (es) 1977-04-20
JPS5225746A (en) 1977-02-25
GB1516414A (en) 1978-07-05
AU510107B2 (en) 1980-06-05
AR211276A1 (es) 1977-11-15
FI762386A7 (es) 1977-02-23
NL7609223A (nl) 1977-02-24
AT353431B (de) 1979-11-12
CA1088932A (en) 1980-11-04
US4241215A (en) 1980-12-23
AU1654576A (en) 1978-02-09
SE424860B (sv) 1982-08-16
ES450866A1 (es) 1977-12-01
BE845404A (fr) 1977-02-21
IE43930L (en) 1977-02-22
IE43930B1 (en) 1981-07-01
US4306095A (en) 1981-12-15
SE7609235L (sv) 1977-02-23
ATA620076A (de) 1979-04-15
NO762708L (es) 1977-02-23

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