ES462221A1 - Procedimiento para preparar pentapeptidos e intermedios - Google Patents

Procedimiento para preparar pentapeptidos e intermedios

Info

Publication number: ES462221A1
Authority: ES; Spain
Prior art keywords: tyr; phe; gly; met; pharmaceutical composition
Prior art date: 1976-09-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES462221A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

KASTIN ABBA JEREM

Original Assignee

KASTIN ABBA JEREM

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-09-01

Filing date

1977-09-01

Publication date

1979-10-01

1977-09-01 Application filed by KASTIN ABBA JEREM filed Critical KASTIN ABBA JEREM

1979-10-01 Publication of ES462221A1 publication Critical patent/ES462221A1/es

Status Expired legal-status Critical Current

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
125000000030 D-alanine group Chemical group [H]N([H])[C@](C([H])([H])[H])(C(=O)[*])[H] 0.000 abstract 2
230000000202 analgesic effect Effects 0.000 abstract 2
BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
DCXYFEDJOCDNAF-UWTATZPHSA-N D-Asparagine Chemical group OC(=O)[C@H](N)CC(N)=O DCXYFEDJOCDNAF-UWTATZPHSA-N 0.000 abstract 1
AGPKZVBTJJNPAG-RFZPGFLSSA-N D-Isoleucine Chemical group CC[C@@H](C)[C@@H](N)C(O)=O AGPKZVBTJJNPAG-RFZPGFLSSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Chemical group OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 abstract 1
MTCFGRXMJLQNBG-UWTATZPHSA-N D-Serine Chemical group OC[C@@H](N)C(O)=O MTCFGRXMJLQNBG-UWTATZPHSA-N 0.000 abstract 1
ODKSFYDXXFIFQN-SCSAIBSYSA-N D-arginine Chemical group OC(=O)[C@H](N)CCCNC(N)=N ODKSFYDXXFIFQN-SCSAIBSYSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-UWTATZPHSA-N D-aspartic acid Chemical group OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-GSVOUGTGSA-N D-glutamic acid Chemical group OC(=O)[C@H](N)CCC(O)=O WHUUTDBJXJRKMK-GSVOUGTGSA-N 0.000 abstract 1
ZDXPYRJPNDTMRX-GSVOUGTGSA-N D-glutamine Chemical group OC(=O)[C@H](N)CCC(N)=O ZDXPYRJPNDTMRX-GSVOUGTGSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-RXMQYKEDSA-N D-leucine Chemical group CC(C)C[C@@H](N)C(O)=O ROHFNLRQFUQHCH-RXMQYKEDSA-N 0.000 abstract 1
KDXKERNSBIXSRK-RXMQYKEDSA-N D-lysine Chemical group NCCCC[C@@H](N)C(O)=O KDXKERNSBIXSRK-RXMQYKEDSA-N 0.000 abstract 1
FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical group CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 abstract 1
COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical group OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 1
AYFVYJQAPQTCCC-STHAYSLISA-N D-threonine Chemical group C[C@H](O)[C@@H](N)C(O)=O AYFVYJQAPQTCCC-STHAYSLISA-N 0.000 abstract 1
QIVBCDIJIAJPQS-SECBINFHSA-N D-tryptophane Chemical group C1=CC=C2C(C[C@@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-SECBINFHSA-N 0.000 abstract 1
OUYCCCASQSFEME-MRVPVSSYSA-N D-tyrosine Chemical group OC(=O)[C@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-MRVPVSSYSA-N 0.000 abstract 1
KZSNJWFQEVHDMF-SCSAIBSYSA-N D-valine Chemical group CC(C)[C@@H](N)C(O)=O KZSNJWFQEVHDMF-SCSAIBSYSA-N 0.000 abstract 1
YFGBQHOOROIVKG-FKBYEOEOSA-N Met-enkephalin Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(O)=O)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 YFGBQHOOROIVKG-FKBYEOEOSA-N 0.000 abstract 1
230000001430 anti-depressive effect Effects 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
150000002741 methionine derivatives Chemical class 0.000 abstract 1
229960005181 morphine Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
- C07K14/702—Enkephalins with at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Zoology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES462221A 1976-09-01 1977-09-01 Procedimiento para preparar pentapeptidos e intermedios Expired ES462221A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US71939776A	1976-09-01	1976-09-01

Publications (1)

Publication Number	Publication Date
ES462221A1 true ES462221A1 (es)	1979-10-01

Family

ID=24889909

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES462221A Expired ES462221A1 (es)	1976-09-01	1977-09-01	Procedimiento para preparar pentapeptidos e intermedios

Country Status (15)

Country	Link
JP (1)	JPS5356634A (da)
AU (1)	AU2844577A (da)
BE (1)	BE858344A (da)
DE (1)	DE2739440A1 (da)
DK (1)	DK386677A (da)
ES (1)	ES462221A1 (da)
FR (2)	FR2364889A1 (da)
IL (1)	IL52870A0 (da)
NL (1)	NL7709653A (da)
NO (1)	NO773013L (da)
PL (1)	PL200605A1 (da)
PT (1)	PT66982B (da)
SE (1)	SE7709806L (da)
YU (1)	YU208677A (da)
ZA (1)	ZA775285B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2359817A1 (fr) *	1976-07-27	1978-02-24	Reckitt & Colmann Prod Ltd	Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
US4259234A (en) *	1976-09-27	1981-03-31	Eli Lilly And Company	Analgesic compounds
GB1604850A (en) *	1977-11-24	1981-12-16	Wellcome Found	Biologically active peptides
US4278596A (en) *	1978-08-08	1981-07-14	American Home Products Corporation	Analgesic pentapeptides
CA1175810A (en) *	1979-03-30	1984-10-09	Frank A. Momany	Synthetic peptides having pituitary growth hormone releasing activity
DE2933947A1 (de) *	1979-08-22	1981-03-12	Hoechst Ag, 6000 Frankfurt	Neue peptidamide und verfahren zu ihrer herstellung.
NL8005121A (nl) *	1979-09-20	1981-03-24	Erba Farmitalia	Biologisch actieve peptiden.
JPS5645450A (en) *	1979-09-21	1981-04-25	Dai Ichi Seiyaku Co Ltd	Pentapeptide compound
DE2941790A1 (de) *	1979-10-16	1981-04-30	Hoechst Ag, 6000 Frankfurt	Verwendung motilitaetssteigernder peptide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1532181A (en) *	1976-02-02	1978-11-15	Beckman Instruments Inc	Pentapetides and a method of preparing them
NZ183712A (en) *	1976-04-08	1979-10-25	Ici Ltd	Polypeptide analogues of enkephalins, and pharmaceutical compositions
US4259234A (en) *	1976-09-27	1981-03-31	Eli Lilly And Company	Analgesic compounds

1977
- 1977-08-31 SE SE7709806A patent/SE7709806L/xx unknown
- 1977-08-31 PT PT66982A patent/PT66982B/pt unknown
- 1977-08-31 DK DK386677A patent/DK386677A/da not_active Application Discontinuation
- 1977-08-31 NO NO773013A patent/NO773013L/no unknown
- 1977-08-31 ZA ZA00775285A patent/ZA775285B/xx unknown
- 1977-09-01 JP JP10536977A patent/JPS5356634A/ja active Pending
- 1977-09-01 IL IL52870A patent/IL52870A0/xx unknown
- 1977-09-01 ES ES462221A patent/ES462221A1/es not_active Expired
- 1977-09-01 FR FR7726563A patent/FR2364889A1/fr active Granted
- 1977-09-01 DE DE19772739440 patent/DE2739440A1/de not_active Withdrawn
- 1977-09-01 BE BE180631A patent/BE858344A/xx unknown
- 1977-09-01 YU YU02086/77A patent/YU208677A/xx unknown
- 1977-09-01 NL NL7709653A patent/NL7709653A/xx not_active Application Discontinuation
- 1977-09-01 AU AU28445/77A patent/AU2844577A/en active Pending
- 1977-09-01 PL PL20060577A patent/PL200605A1/xx unknown
1978
- 1978-06-02 FR FR7816543A patent/FR2381746A1/fr not_active Withdrawn

Also Published As

Publication number	Publication date
PT66982A (en)	1977-09-01
ZA775285B (en)	1978-07-26
IL52870A0 (en)	1977-11-30
DE2739440A1 (de)	1978-03-02
BE858344A (fr)	1978-01-02
FR2364889B1 (da)	1981-06-19
PT66982B (en)	1979-02-13
DK386677A (da)	1978-03-02
NO773013L (no)	1978-03-02
NL7709653A (nl)	1978-03-03
FR2364889A1 (fr)	1978-04-14
AU2844577A (en)	1979-03-08
YU208677A (en)	1982-08-31
PL200605A1 (pl)	1979-02-12
SE7709806L (sv)	1978-03-02
JPS5356634A (en)	1978-05-23
FR2381746A1 (fr)	1978-09-22

Publication	Publication Date	Title
ES430495A1 (es)	1977-01-16	Un metodo para preparar amidas de monapeptidos.
SE7502520L (da)	1975-09-09
FR2364889A1 (fr)	1978-04-14	Nouveaux derives encephaliniques a la methionine
FR2347336A1 (fr)	1977-11-04	Derives peptidiques
KR850001230A (ko)	1985-03-16	옥타펩티드 바조프레신 길항물질의 제조방법
KR840002772A (ko)	1984-07-16	뇌하수체 성장호르몬 유리작용을 지닌 펩타이드의 합성방법
FR2325427A1 (fr)	1977-04-22	Catalyseur de reformage d'hydrocarbures avec de la vapeur d'eau, et a son application a la production de gaz contenant du methane
ES2125526T3 (es)	1999-03-01	Catalizador de aleacion de platino para pilas de combustible y procedimiento para su preparacion.
DK0779076T3 (da)	2005-07-11	Peptid, en fremgangsmåde til fremstilling af det og en farmaceutisk forbindelse baseret på det
GB1512433A (en)	1978-06-01	Peptides having lh-rh/fsh-rh activity and process for preparing them
RU94024278A (ru)	1997-11-10	Пептид и способ его получения
ATE6504T1 (de)	1984-03-15	Polypeptide.
GB1530560A (en)	1978-11-01	Cyclic hexapeptides
HUP0300222A2 (hu)	2003-07-28	Új LHRH-antagonisták, a vegyületek előállítása és gyógyszerként való alkalmazása
RU2006111491A (ru)	2007-11-20	Новые противоопухолевые соединения
FR2359817A1 (fr)	1978-02-24	Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
NO801061L (no)	1980-10-13	Peptider med tymopoietin-lignende aktivitet
ES458537A1 (es)	1978-04-01	Procedimiento para preparar encefalinas 2-y-3-sustituidas.
EP0138604A3 (en)	1987-04-01	Arginine vasopressin antagonists
ATE33659T1 (de)	1988-05-15	Basische hexa- und heptapeptide als vasopressin- antagonisten.
EP0151016A3 (en)	1987-04-01	Arginine vasopressin antagonists
CN208996838U (zh)	2019-06-18	一种用于内燃机在受限环境下的供氧装置
EP0189326A3 (en)	1988-10-26	Derivatives of arginine vasopressin antagonists
GB1523812A (en)	1978-09-06	Polypeptide
GB2010280A (en)	1979-06-27	Somatostatin analogs