ES469496A1 - Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos - Google Patents

Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos

Info

Publication number
ES469496A1
ES469496A1 ES469496A ES469496A ES469496A1 ES 469496 A1 ES469496 A1 ES 469496A1 ES 469496 A ES469496 A ES 469496A ES 469496 A ES469496 A ES 469496A ES 469496 A1 ES469496 A1 ES 469496A1
Authority
ES
Spain
Prior art keywords
phenoxyalkoxy
aryloxy
esters
acetic acid
phenyl acetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES469496A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES469496A1 publication Critical patent/ES469496A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Nuevas composiciones de materia que contienen compuestos útiles como agentes hipolipidémicos, así como el método para rebajar esterol del suero. Se ha dedicado un esfuerzo considerable en los últimos años para obtener sustancias que sean de utilidad en el tratamiento de la hiperlipidemia, un estado asociado con elevados niveles en la sangre de colesterol, fosfolípidos y/o triglicéridos. Este estado viene asociado con diversas enfermedades, siendo una de las más serias la aterosclerosis. Los medicamentos usados para rebajar los niveles en sangre de colesterol, fosfolípidos y triglicéridos se denominan productos hipolipidémicos. En la actualidad se dispone de tres agentes principales disminuidores del nivel de lípidos, a saber clofibrato, D-tiroxina, y ácido nicotínico.
ES469496A 1977-05-06 1978-05-05 Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos Expired ES469496A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/794,510 US4125732A (en) 1977-05-06 1977-05-06 2-Aryloxy-2-(phenoxyalkoxy)phenyl acetic acid and esters

Publications (1)

Publication Number Publication Date
ES469496A1 true ES469496A1 (es) 1979-09-16

Family

ID=25162842

Family Applications (2)

Application Number Title Priority Date Filing Date
ES469496A Expired ES469496A1 (es) 1977-05-06 1978-05-05 Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos
ES471826A Expired ES471826A1 (es) 1977-05-06 1978-07-18 Procedimiento para preparar acidos y esteres 2-ariloxi-2- (parafenoxialcoxi)fenilaceticossustituidos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES471826A Expired ES471826A1 (es) 1977-05-06 1978-07-18 Procedimiento para preparar acidos y esteres 2-ariloxi-2- (parafenoxialcoxi)fenilaceticossustituidos.

Country Status (18)

Country Link
US (1) US4125732A (es)
JP (1) JPS53137928A (es)
AU (1) AU3515778A (es)
BE (1) BE866721A (es)
CU (1) CU34914A (es)
DD (1) DD136134A5 (es)
DE (1) DE2819263A1 (es)
DK (1) DK197878A (es)
ES (2) ES469496A1 (es)
FI (1) FI781298A7 (es)
FR (1) FR2389594B1 (es)
IL (1) IL54488A0 (es)
IT (1) IT1105289B (es)
NL (1) NL7804504A (es)
PL (1) PL206611A1 (es)
PT (1) PT68000B (es)
SE (1) SE7805185L (es)
ZA (1) ZA782041B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1201127A (en) * 1982-09-10 1986-02-25 Katsuhiro Uchida Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
US4983628A (en) * 1983-10-27 1991-01-08 Merck Frosst Canada, Inc. Leukotriene antagonists
US4683325A (en) * 1984-01-23 1987-07-28 Merck Frosst Canada, Inc. Leukotriene antagonists
FI870445A7 (fi) * 1985-06-14 1987-02-02 Pfizer Välituote asymmetrisen hydantoiinin valmistuksessa.
WO2002009651A2 (en) * 2000-08-02 2002-02-07 Smithkline Beecham Corporation Fatty acid synthase inhibitors
EP1366012A4 (en) * 2001-02-09 2005-11-02 Merck & Co Inc 2-ARYLOXY-2-ARYLALKANIC ACIDS AGAINST DIABETES AND FAILURE CHANGES
UA87467C2 (xx) 2003-09-19 2009-07-27 Янссен Фармацевтика Н.В 4-((феноксіалкіл)тіо)феноксіоцтова кислота та її аналоги$4-((феноксиалкил)тио)феноксиуксусная кислота и ее аналоги
CA2539403C (en) * 2003-09-19 2013-11-19 Janssen Pharmaceutica N.V. 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
MY147518A (en) * 2004-09-15 2012-12-31 Janssen Pharmaceutica Nv 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
MY145712A (en) * 2004-09-15 2012-03-30 Janssen Pharmaceutica Nv 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
US7161026B1 (en) 2005-07-08 2007-01-09 Property Development Corporation International, Ltd, Inc. Method of preparation of methyl-benzyl-ketone
JO3006B1 (ar) * 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك
PE20080188A1 (es) * 2006-04-18 2008-03-10 Janssen Pharmaceutica Nv Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA755105A (en) * 1967-03-21 A. Bolhofer William Alpha-phenoxy and alpha-phenylthio carboxylic acids

Also Published As

Publication number Publication date
PT68000B (en) 1979-10-22
FI781298A7 (fi) 1978-11-07
ES471826A1 (es) 1979-10-16
DK197878A (da) 1978-11-07
ZA782041B (en) 1979-03-28
SE7805185L (sv) 1978-11-07
CU34914A (es) 1980-10-30
PT68000A (en) 1978-06-01
PL206611A1 (pl) 1979-12-17
FR2389594B1 (es) 1980-10-31
IT7849200A0 (it) 1978-05-04
FR2389594A1 (es) 1978-12-01
DD136134A5 (de) 1979-06-20
JPS53137928A (en) 1978-12-01
NL7804504A (nl) 1978-11-08
DE2819263A1 (de) 1978-11-16
IT1105289B (it) 1985-10-28
IL54488A0 (en) 1978-07-31
BE866721A (fr) 1978-11-06
AU3515778A (en) 1979-10-25
US4125732A (en) 1978-11-14

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