ES471826A1 - Procedimiento para preparar acidos y esteres 2-ariloxi-2- (parafenoxialcoxi)fenilaceticossustituidos. - Google Patents
Procedimiento para preparar acidos y esteres 2-ariloxi-2- (parafenoxialcoxi)fenilaceticossustituidos.Info
- Publication number
- ES471826A1 ES471826A1 ES471826A ES471826A ES471826A1 ES 471826 A1 ES471826 A1 ES 471826A1 ES 471826 A ES471826 A ES 471826A ES 471826 A ES471826 A ES 471826A ES 471826 A1 ES471826 A1 ES 471826A1
- Authority
- ES
- Spain
- Prior art keywords
- phenoxyalkoxy
- aryloxy
- esters
- acetic acid
- phenyl acetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 title abstract 3
- 150000002148 esters Chemical class 0.000 title abstract 2
- 235000019439 ethyl acetate Nutrition 0.000 title 1
- 229960003424 phenylacetic acid Drugs 0.000 title 1
- 239000003279 phenylacetic acid Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento para preparar ácidos y ésteres 2-ariloxi-2-(para-fenoxialcoxi)fenilacéticos sustituidos, de fórmula **(Fórmula)** en donde R1 es flúor, cloro, trifluormetilo o terc.-butilo; R2 es alquilo de cadena recta con hasta 6 átomos de carbono; R3 es hidrógeno o alquilo con hasta 4 átomos de carbono; Z es un radical divalente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/794,510 US4125732A (en) | 1977-05-06 | 1977-05-06 | 2-Aryloxy-2-(phenoxyalkoxy)phenyl acetic acid and esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES471826A1 true ES471826A1 (es) | 1979-10-16 |
Family
ID=25162842
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469496A Expired ES469496A1 (es) | 1977-05-06 | 1978-05-05 | Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos |
| ES471826A Expired ES471826A1 (es) | 1977-05-06 | 1978-07-18 | Procedimiento para preparar acidos y esteres 2-ariloxi-2- (parafenoxialcoxi)fenilaceticossustituidos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469496A Expired ES469496A1 (es) | 1977-05-06 | 1978-05-05 | Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4125732A (es) |
| JP (1) | JPS53137928A (es) |
| AU (1) | AU3515778A (es) |
| BE (1) | BE866721A (es) |
| CU (1) | CU34914A (es) |
| DD (1) | DD136134A5 (es) |
| DE (1) | DE2819263A1 (es) |
| DK (1) | DK197878A (es) |
| ES (2) | ES469496A1 (es) |
| FI (1) | FI781298A7 (es) |
| FR (1) | FR2389594B1 (es) |
| IL (1) | IL54488A0 (es) |
| IT (1) | IT1105289B (es) |
| NL (1) | NL7804504A (es) |
| PL (1) | PL206611A1 (es) |
| PT (1) | PT68000B (es) |
| SE (1) | SE7805185L (es) |
| ZA (1) | ZA782041B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1201127A (en) * | 1982-09-10 | 1986-02-25 | Katsuhiro Uchida | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same |
| US4683325A (en) * | 1984-01-23 | 1987-07-28 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| US4983628A (en) * | 1983-10-27 | 1991-01-08 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| WO1986007353A1 (en) * | 1985-06-14 | 1986-12-18 | Pfizer Inc. | Intermediate in the production of an asymmetric hydantoin |
| WO2002009651A2 (en) * | 2000-08-02 | 2002-02-07 | Smithkline Beecham Corporation | Fatty acid synthase inhibitors |
| CA2437118A1 (en) * | 2001-02-09 | 2002-08-22 | Merck & Co., Inc. | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders |
| DE602004028500D1 (de) * | 2003-09-19 | 2010-09-16 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyessigsäuren und analoga |
| WO2005042478A2 (en) | 2003-09-19 | 2005-05-12 | Janssen Pharmaceutica, N.V. | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| MY145712A (en) * | 2004-09-15 | 2012-03-30 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| US7161026B1 (en) | 2005-07-08 | 2007-01-09 | Property Development Corporation International, Ltd, Inc. | Method of preparation of methyl-benzyl-ketone |
| JO3006B1 (ar) * | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| PE20080188A1 (es) * | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA755105A (en) * | 1967-03-21 | A. Bolhofer William | Alpha-phenoxy and alpha-phenylthio carboxylic acids |
-
1977
- 1977-05-06 US US05/794,510 patent/US4125732A/en not_active Expired - Lifetime
-
1978
- 1978-04-10 ZA ZA00782041A patent/ZA782041B/xx unknown
- 1978-04-12 IL IL54488A patent/IL54488A0/xx unknown
- 1978-04-17 AU AU35157/78A patent/AU3515778A/en active Pending
- 1978-04-26 FI FI781298A patent/FI781298A7/fi not_active Application Discontinuation
- 1978-04-26 NL NL7804504A patent/NL7804504A/xx not_active Application Discontinuation
- 1978-05-02 DE DE19782819263 patent/DE2819263A1/de not_active Withdrawn
- 1978-05-04 IT IT49200/78A patent/IT1105289B/it active
- 1978-05-05 DK DK197878A patent/DK197878A/da unknown
- 1978-05-05 PT PT68000A patent/PT68000B/pt unknown
- 1978-05-05 PL PL20661178A patent/PL206611A1/xx unknown
- 1978-05-05 DD DD78205215A patent/DD136134A5/xx unknown
- 1978-05-05 SE SE7805185A patent/SE7805185L/xx unknown
- 1978-05-05 BE BE187405A patent/BE866721A/xx unknown
- 1978-05-05 FR FR7813417A patent/FR2389594B1/fr not_active Expired
- 1978-05-05 ES ES469496A patent/ES469496A1/es not_active Expired
- 1978-05-06 JP JP5399878A patent/JPS53137928A/ja active Pending
- 1978-05-06 CU CU7834914A patent/CU34914A/es unknown
- 1978-07-18 ES ES471826A patent/ES471826A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK197878A (da) | 1978-11-07 |
| PL206611A1 (pl) | 1979-12-17 |
| IL54488A0 (en) | 1978-07-31 |
| AU3515778A (en) | 1979-10-25 |
| FR2389594A1 (es) | 1978-12-01 |
| DE2819263A1 (de) | 1978-11-16 |
| IT7849200A0 (it) | 1978-05-04 |
| FR2389594B1 (es) | 1980-10-31 |
| FI781298A7 (fi) | 1978-11-07 |
| ES469496A1 (es) | 1979-09-16 |
| IT1105289B (it) | 1985-10-28 |
| CU34914A (es) | 1980-10-30 |
| PT68000B (en) | 1979-10-22 |
| BE866721A (fr) | 1978-11-06 |
| SE7805185L (sv) | 1978-11-07 |
| NL7804504A (nl) | 1978-11-08 |
| US4125732A (en) | 1978-11-14 |
| DD136134A5 (de) | 1979-06-20 |
| JPS53137928A (en) | 1978-12-01 |
| ZA782041B (en) | 1979-03-28 |
| PT68000A (en) | 1978-06-01 |
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