ES472335A1 - Un procedimiento para la preparacion de eteres del acido clavulanico - Google Patents

Un procedimiento para la preparacion de eteres del acido clavulanico

Info

Publication number: ES472335A1
Authority: ES; Spain
Prior art keywords: preparation; clavulanic acid; ethers; esters; salts
Prior art date: 1977-08-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES472335A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Beecham Group PLC

Original Assignee

Beecham Group PLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-08-04

Filing date

1978-08-03

Publication date

1980-03-01

1978-08-03 Application filed by Beecham Group PLC filed Critical Beecham Group PLC

1980-03-01 Publication of ES472335A1 publication Critical patent/ES472335A1/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 4
HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 3
HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 3
229960003324 clavulanic acid Drugs 0.000 title abstract 3
150000002170 ethers Chemical class 0.000 title 1
150000002148 esters Chemical class 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
POLCUAVZOMRGSN-UHFFFAOYSA-N dipropyl ether Chemical class CCCOCCC POLCUAVZOMRGSN-UHFFFAOYSA-N 0.000 abstract 2
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
UUFQTNFCRMXOAE-UHFFFAOYSA-N 1-methylmethylene Chemical group C[CH] UUFQTNFCRMXOAE-UHFFFAOYSA-N 0.000 abstract 1
108090000204 Dipeptidase 1 Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
102000006635 beta-lactamase Human genes 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)

ES472335A 1977-08-04 1978-08-03 Un procedimiento para la preparacion de eteres del acido clavulanico Expired ES472335A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB3269977		1977-08-04

Publications (1)

Publication Number	Publication Date
ES472335A1 true ES472335A1 (es)	1980-03-01

Family

ID=10342695

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES472335A Expired ES472335A1 (es)	1977-08-04	1978-08-03	Un procedimiento para la preparacion de eteres del acido clavulanico

Country Status (6)

Country	Link
EP (1)	EP0000804B1 (fr)
JP (1)	JPS5427595A (fr)
CA (1)	CA1107739A (fr)
DE (1)	DE2862385D1 (fr)
ES (1)	ES472335A1 (fr)
IT (1)	IT1106618B (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1501643A (en) *	1974-10-28	1978-02-22	Beecham Group Ltd	Antibacterial substituted azetidinones
GB1565209A (en) *	1975-10-13	1980-04-16	Beecham Group Ltd	Clavulanic acid derivatives
US4230622A (en) *	1975-12-17	1980-10-28	Glaxo Laboratories Limited	Halogen derivatives of clavulaic acid

1978
- 1978-07-10 EP EP78300135A patent/EP0000804B1/fr not_active Expired
- 1978-07-10 DE DE7878300135T patent/DE2862385D1/de not_active Expired
- 1978-07-27 CA CA308,302A patent/CA1107739A/fr not_active Expired
- 1978-08-01 JP JP9501178A patent/JPS5427595A/ja active Pending
- 1978-08-02 IT IT50575/78A patent/IT1106618B/it active
- 1978-08-03 ES ES472335A patent/ES472335A1/es not_active Expired

Also Published As

Publication number	Publication date
JPS5427595A (en)	1979-03-01
EP0000804B1 (fr)	1984-03-07
IT1106618B (it)	1985-11-11
CA1107739A (fr)	1981-08-25
DE2862385D1 (en)	1984-04-12
IT7850575A0 (it)	1978-08-02
EP0000804A1 (fr)	1979-02-21

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