ES8101580A1 - Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico - Google Patents

Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico

Info

Publication number
ES8101580A1
ES8101580A1 ES488141A ES488141A ES8101580A1 ES 8101580 A1 ES8101580 A1 ES 8101580A1 ES 488141 A ES488141 A ES 488141A ES 488141 A ES488141 A ES 488141A ES 8101580 A1 ES8101580 A1 ES 8101580A1
Authority
ES
Spain
Prior art keywords
americanin
present
compounds
provides
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES488141A
Other languages
English (en)
Other versions
ES488141A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Madaus GmbH and Co filed Critical Dr Madaus GmbH and Co
Publication of ES8101580A1 publication Critical patent/ES8101580A1/es
Publication of ES488141A0 publication Critical patent/ES488141A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE UN DERIVADO DEL ALDEHIDO 3,4-DIHIDROXICINAMICO. CONSTA DE LAS SIGUIENTES OPERACIONES: 1) EXTRACCION CON ACETONA DE FRUTOS SECOS DE LAS ESPECIES DE PHYTOLACCA, DESPUES DE SER FINAMENTE TRITURADOS Y TRATADOS CON ETER. 2) PURIFICACION CON CLOROFORMO DE LOS RESIDUOS DEL EXTRACTO EVAPORADO A SEQUEDAD, SEGUIDO DE DISOLUCION DE N-BUTANOL. 3) PURIFICACION CON AGUA DE LA SOLUCION OBTENIDA SEGUIDO DE EVAPORACION A SEQUEDAD Y DISOLUCION DEL RESIDUO EN ACETONA. 4) CROMATOGRAFIA EN COLUMNA SOBRE SEPHADEX LH20 DE LA SOLUCION DE ACETONA, EMPLEANDO ACETONA COMO AGENTE DE ELUCION. 5) LAS FRACCIONES FARMACOLOGICAMENTE EFICACES SON REUNIDAS Y EVAPORADAS A SEQUEDAD Y EL RESIDUO ES RECRISTALIZADO A PARTIR DE METANOL. EL COMPUESTO QUE SE OBTIENE TIENE DE FORMULA GENERAL (I). *FORMULA*
ES488141A 1978-09-16 1980-01-31 Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico Granted ES488141A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782840467 DE2840467A1 (de) 1978-09-16 1978-09-16 3,4-dihydroxizimtaldehydderivat, dessen herstellung und arzneimittel

Publications (2)

Publication Number Publication Date
ES8101580A1 true ES8101580A1 (es) 1980-12-16
ES488141A0 ES488141A0 (es) 1980-12-16

Family

ID=6049691

Family Applications (3)

Application Number Title Priority Date Filing Date
ES484202A Expired ES8101578A1 (es) 1978-09-16 1979-09-15 Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico
ES488140A Granted ES488140A0 (es) 1978-09-16 1980-01-31 Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico
ES488141A Granted ES488141A0 (es) 1978-09-16 1980-01-31 Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES484202A Expired ES8101578A1 (es) 1978-09-16 1979-09-15 Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico
ES488140A Granted ES488140A0 (es) 1978-09-16 1980-01-31 Procedimiento para la obtencion de un derivado del aldehido 3,4-dihidroxicinamico

Country Status (18)

Country Link
JP (1) JPS5559182A (es)
AR (3) AR221900A1 (es)
AT (1) AT367417B (es)
BE (1) BE878824A (es)
CA (1) CA1128532A (es)
CS (3) CS221521B2 (es)
DE (1) DE2840467A1 (es)
ES (3) ES8101578A1 (es)
FR (1) FR2436145A1 (es)
GB (1) GB2035300B (es)
IT (1) IT7925651A0 (es)
LU (1) LU81679A1 (es)
NL (1) NL7906881A (es)
PL (1) PL120977B1 (es)
PT (1) PT70177A (es)
SE (1) SE7907656L (es)
SU (1) SU925246A3 (es)
ZA (1) ZA794815B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2851919A1 (fr) * 2003-03-03 2004-09-10 Lmd Lignanes utilisables comme inhibiteurs de cathepsines et leurs applications

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428680C2 (de) * 1974-06-14 1983-02-17 Dr. Madaus & Co, 5000 Köln 1-(2',4',6'-Trihydroxyphenyl)-propandion-(1,2)-Verbindungen, Verfahren zu deren Herstellung und Arzneimittel, die diese Verbindungen enthalten

Also Published As

Publication number Publication date
PT70177A (de) 1979-10-01
BE878824A (fr) 1980-03-17
GB2035300A (en) 1980-06-18
CS221522B2 (en) 1983-04-29
ATA607979A (de) 1981-11-15
DE2840467A1 (de) 1980-03-20
CS221523B2 (en) 1983-04-29
PL218339A1 (es) 1980-12-01
ZA794815B (en) 1980-10-29
SU925246A3 (ru) 1982-04-30
AR225070A1 (es) 1982-02-15
AR221900A1 (es) 1981-03-31
CA1128532A (en) 1982-07-27
ES484202A0 (es) 1980-12-16
AT367417B (de) 1982-07-12
ES8101579A1 (es) 1980-12-16
AR226094A1 (es) 1982-05-31
GB2035300B (en) 1983-03-23
ES8101578A1 (es) 1980-12-16
PL120977B1 (en) 1982-04-30
NL7906881A (nl) 1980-03-18
JPS5559182A (en) 1980-05-02
SE7907656L (sv) 1980-03-17
IT7925651A0 (it) 1979-09-12
ES488140A0 (es) 1980-12-16
CS221521B2 (en) 1983-04-29
LU81679A1 (de) 1980-01-24
FR2436145A1 (fr) 1980-04-11
ES488141A0 (es) 1980-12-16

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