ES472812A1 - Procedimiento para la preparacion de nuevas 1-piperazinil-4h-s-triazolo (3,4c)tieno (2,3e)1,4-diazepinas sustituidas - Google Patents

Procedimiento para la preparacion de nuevas 1-piperazinil-4h-s-triazolo (3,4c)tieno (2,3e)1,4-diazepinas sustituidas

Info

Publication number
ES472812A1
ES472812A1 ES472812A ES472812A ES472812A1 ES 472812 A1 ES472812 A1 ES 472812A1 ES 472812 A ES472812 A ES 472812A ES 472812 A ES472812 A ES 472812A ES 472812 A1 ES472812 A1 ES 472812A1
Authority
ES
Spain
Prior art keywords
radical
diazepines
thieno
triazolo
piperazinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472812A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C.H. Boehringer Sohn AG and Co KG
Original Assignee
C.H. Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19772732943 external-priority patent/DE2732943A1/de
Priority claimed from DE19772732921 external-priority patent/DE2732921A1/de
Application filed by C.H. Boehringer Sohn AG and Co KG filed Critical C.H. Boehringer Sohn AG and Co KG
Publication of ES472812A1 publication Critical patent/ES472812A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la preparación de nuevas 1-piperazinil-4H-s-triazolo[3,4c]tieno[2,3e]1,4-diazepinas sustituidas de la fórmula general **(Fórmula)** en la que R1 significa hidrógeno, un radical alcohilo, halogenoalcohilo, hiroxialcohilo o dialcohilaminoalcoitilo de cadena recta o ramificado, un radical fenilo eventualmente sustituido con metilo, metoxi, nitro o halógeno o un radical piridilo o pirimidinilo, o el radical R4-CO-; R2 significa hidrógeno, fluor, cloro o bromo; R3 significa cloro o bromo o un radical alcohilo; y R4 significa hidrógeno, alcohilo con 1 a 17 átomos de carbono, alcoxi con 1 a 2 átomos decarbono, fenilo, tolilo, metoxifenilo, halogenofenilo, nitrofenilo o piridilo.
ES472812A 1977-07-21 1978-08-24 Procedimiento para la preparacion de nuevas 1-piperazinil-4h-s-triazolo (3,4c)tieno (2,3e)1,4-diazepinas sustituidas Expired ES472812A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772732943 DE2732943A1 (de) 1977-07-21 1977-07-21 Neue substituierte 1-piperazinyl- 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE19772732921 DE2732921A1 (de) 1977-07-21 1977-07-21 Neue substituierte 1-acyl-piperidino- bzw. -piperazino-4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4- diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (1)

Publication Number Publication Date
ES472812A1 true ES472812A1 (es) 1979-02-16

Family

ID=25772369

Family Applications (2)

Application Number Title Priority Date Filing Date
ES471886A Expired ES471886A1 (es) 1977-07-21 1978-07-20 Procedimiento para la preparacion de nuevas 1-piperazinil- 4h-s-triazolo (3,4c)tieno (2,3 e) 1,4-diazepinas sustituidas
ES472812A Expired ES472812A1 (es) 1977-07-21 1978-08-24 Procedimiento para la preparacion de nuevas 1-piperazinil-4h-s-triazolo (3,4c)tieno (2,3e)1,4-diazepinas sustituidas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES471886A Expired ES471886A1 (es) 1977-07-21 1978-07-20 Procedimiento para la preparacion de nuevas 1-piperazinil- 4h-s-triazolo (3,4c)tieno (2,3 e) 1,4-diazepinas sustituidas

Country Status (30)

Country Link
US (1) US4180573A (es)
EP (1) EP0000479B1 (es)
JP (1) JPS5422395A (es)
AT (1) AT363949B (es)
AU (1) AU515885B2 (es)
CA (1) CA1087182A (es)
CH (1) CH642374A5 (es)
CS (1) CS209897B2 (es)
DD (1) DD137934A5 (es)
DE (1) DE2860404D1 (es)
DK (1) DK150306C (es)
ES (2) ES471886A1 (es)
FI (1) FI63033C (es)
FR (1) FR2398070A1 (es)
GB (1) GB2001972B (es)
GR (1) GR65022B (es)
HU (1) HU176485B (es)
IE (1) IE47336B1 (es)
IL (1) IL55169A (es)
IT (1) IT1107490B (es)
LU (1) LU80002A1 (es)
NL (1) NL7807762A (es)
NO (1) NO149889C (es)
NZ (1) NZ187915A (es)
PH (1) PH14236A (es)
PL (1) PL115061B1 (es)
PT (1) PT68330A (es)
RO (1) RO75609A (es)
SE (1) SE439920B (es)
SU (2) SU725564A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2830782A1 (de) * 1978-07-13 1980-01-24 Boehringer Sohn Ingelheim Neue substituierte 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
ES2037013T3 (es) * 1986-01-21 1993-06-16 Boehringer Ingelheim Kg Procedimiento para preparar tieno-1,4-diazepinas.
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
US3894025A (en) * 1974-03-21 1975-07-08 Upjohn Co 1-Piperazino-6-phenyl-4H-s-triazolo{8 4,3-a{9 {8 1,4{9 -benzodiazepine compounds
JPS5747916B2 (es) * 1974-05-13 1982-10-13
DE2503235A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Neues verfahren zur herstellung von 8-brom-thieno-triazolo-1,4-diazepinen
DE2533924C3 (de) * 1975-07-30 1979-05-03 C.H. Boehringer Sohn, 6507 Ingelheim Verfahren zur Herstellung von 6- Aryl-4H-striazolo [3,4-c] thieno [2,3-e] 1,4-diazepinen
DE2531678C3 (de) * 1975-07-16 1979-06-28 C.H. Boehringer Sohn, 6507 Ingelheim Thieno [2,3e] triazole [3,4c] 5,6-dihydro-l,4diazepine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
SU725564A3 (en) 1980-03-30
ATA498978A (de) 1981-02-15
NO782499L (no) 1979-01-23
GB2001972A (en) 1979-02-14
NL7807762A (nl) 1979-01-23
PH14236A (en) 1981-04-09
DK150306B (da) 1987-02-02
AU515885B2 (en) 1981-05-07
NO149889C (no) 1984-07-11
GR65022B (en) 1980-06-16
EP0000479B1 (de) 1981-01-07
ES471886A1 (es) 1979-02-01
SE7808019L (sv) 1979-01-22
PL208542A1 (pl) 1979-06-04
RO75609A (ro) 1981-01-30
GB2001972B (en) 1982-01-06
EP0000479A1 (de) 1979-02-07
DK325178A (da) 1979-01-22
AU3820978A (en) 1980-01-24
DE2860404D1 (en) 1981-02-26
LU80002A1 (de) 1979-09-06
IE781456L (en) 1979-01-21
FI63033B (fi) 1982-12-31
IT7850381A0 (it) 1978-07-19
NO149889B (no) 1984-04-02
FR2398070B1 (es) 1982-05-21
JPS5422395A (en) 1979-02-20
IL55169A (en) 1982-04-30
DD137934A5 (de) 1979-10-03
US4180573A (en) 1979-12-25
CH642374A5 (de) 1984-04-13
IL55169A0 (en) 1978-09-29
DK150306C (da) 1987-11-09
FI63033C (fi) 1983-04-11
SE439920B (sv) 1985-07-08
AT363949B (de) 1981-09-10
FI782025A7 (fi) 1979-01-22
CA1087182A (en) 1980-10-07
JPS6254114B2 (es) 1987-11-13
PT68330A (de) 1978-08-01
SU725564A1 (ru) 1980-03-30
SU793402A3 (ru) 1980-12-30
PL115061B1 (en) 1981-03-31
FR2398070A1 (fr) 1979-02-16
NZ187915A (en) 1980-10-08
CS209897B2 (en) 1981-12-31
IE47336B1 (en) 1984-02-22
HU176485B (en) 1981-03-28
IT1107490B (it) 1985-11-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201