ES474468A1 - Procedimiento para la preparacion de piperacina -1-(n-aril- n'-cianocarboximidamidas 4-substituidas - Google Patents

Procedimiento para la preparacion de piperacina -1-(n-aril- n'-cianocarboximidamidas 4-substituidas

Info

Publication number
ES474468A1
ES474468A1 ES474468A ES474468A ES474468A1 ES 474468 A1 ES474468 A1 ES 474468A1 ES 474468 A ES474468 A ES 474468A ES 474468 A ES474468 A ES 474468A ES 474468 A1 ES474468 A1 ES 474468A1
Authority
ES
Spain
Prior art keywords
carbon atoms
aryl
procedure
preparation
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES474468A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fermion Oy
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Publication of ES474468A1 publication Critical patent/ES474468A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la preparación de piperazina-1-(N-aril-N''-ciano)-carboximidamidas 4-substituidas, de la fórmula general **(Fórmula)** en donde R1 representa hidrógeno o metoxilo y R2 representa alquenilo con 3 a 5 átomos de carbono, benzoilo, furoilo, tienil-carbonilo, ciclopentil-carbonilo, alcoxi-carbonilo con 2 a 5 átomos de carbono, alqueniloxicarbonilo con 4 ó 5 átomos de carbono, (2-hidroxi-alcoxi)-carbonilo con 4 ó 54 átomos de carbono.
ES474468A 1977-10-25 1978-10-24 Procedimiento para la preparacion de piperacina -1-(n-aril- n'-cianocarboximidamidas 4-substituidas Expired ES474468A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI773167A FI56836C (fi) 1977-10-25 1977-10-25 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner

Publications (1)

Publication Number Publication Date
ES474468A1 true ES474468A1 (es) 1979-10-16

Family

ID=8511168

Family Applications (1)

Application Number Title Priority Date Filing Date
ES474468A Expired ES474468A1 (es) 1977-10-25 1978-10-24 Procedimiento para la preparacion de piperacina -1-(n-aril- n'-cianocarboximidamidas 4-substituidas

Country Status (6)

Country Link
JP (1) JPS55341A (es)
ES (1) ES474468A1 (es)
FI (1) FI56836C (es)
NL (1) NL7804136A (es)
PT (1) PT68690A (es)
ZA (1) ZA785321B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6245667A (ja) * 1985-08-22 1987-02-27 Shin Etsu Chem Co Ltd 塗料組成物
US4889179A (en) * 1987-11-25 1989-12-26 J. R. Microwave, Inc. Two wire adaptive system for interconnecting a four wire thermostat and a four wire, heating/cooling system
YU70890A (en) * 1989-04-21 1992-05-28 Egyt Gyogyszervegyeszeti Gyar Process for obtaining quinazoline derivatives
PT1556354E (pt) * 2002-06-28 2008-04-17 Euro Celtique Sa Derivados de piperazina úteis como agentes terapêuticos para o tratamento da dor
US7262194B2 (en) 2002-07-26 2007-08-28 Euro-Celtique S.A. Therapeutic agents useful for treating pain
GB0706793D0 (en) * 2007-04-05 2007-05-16 Evotec Ag Compounds

Also Published As

Publication number Publication date
PT68690A (en) 1978-11-01
FI56836C (fi) 1980-04-10
FI773167A7 (fi) 1979-04-26
JPS55341A (en) 1980-01-05
ZA785321B (en) 1979-10-31
NL7804136A (nl) 1979-04-27
FI56836B (fi) 1979-12-31

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