ES474785A1 - Un procedimiento para la preparacion de compuestos derivadosde 1-(naftiletil)imidazol - Google Patents

Un procedimiento para la preparacion de compuestos derivadosde 1-(naftiletil)imidazol

Info

Publication number
ES474785A1
ES474785A1 ES474785A ES474785A ES474785A1 ES 474785 A1 ES474785 A1 ES 474785A1 ES 474785 A ES474785 A ES 474785A ES 474785 A ES474785 A ES 474785A ES 474785 A1 ES474785 A1 ES 474785A1
Authority
ES
Spain
Prior art keywords
imidazole
naftiletil
procedure
preparation
compounds derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES474785A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/848,548 external-priority patent/US4150153A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES474785A1 publication Critical patent/ES474785A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un procedimiento para la preparación de compuestos derivados de 1-(naftiletil) imidazol, de la fórmula general (I) **fórmula** en donde Z es hidroximetileno esterificado , o carbonilo cetal, tiocetal- o heitiocetal-protegido o una sal de adición de ácido aceptable en farmacia, caracterizado porque comprende hacer reaccionar un compuesto de la fórmula **fórmula** en donde X es halo, con una sal de metal alcalino de imidazol, para obtener un compuesto de la fórmula (I) en donde Z es carbonilo cetal protegido
ES474785A 1977-11-04 1978-11-03 Un procedimiento para la preparacion de compuestos derivadosde 1-(naftiletil)imidazol Expired ES474785A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/848,548 US4150153A (en) 1977-05-13 1977-11-04 1-(Naphthylethyl)imidazole derivatives

Publications (1)

Publication Number Publication Date
ES474785A1 true ES474785A1 (es) 1979-11-01

Family

ID=25303594

Family Applications (1)

Application Number Title Priority Date Filing Date
ES474785A Expired ES474785A1 (es) 1977-11-04 1978-11-03 Un procedimiento para la preparacion de compuestos derivadosde 1-(naftiletil)imidazol

Country Status (5)

Country Link
EP (1) EP0001926B1 (es)
JP (1) JPS5481269A (es)
DE (1) DE2860670D1 (es)
ES (1) ES474785A1 (es)
IT (1) IT1160898B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4277486A (en) * 1979-03-09 1981-07-07 Syntex (U.S.A.) Inc. 1-[(Substituted-naphthyl)ethyl]-imidazole derivatives
US4384879A (en) * 1980-07-15 1983-05-24 Ciba-Geigy Corporation 4-(1H-Azolylmethyl)-1,3-dioxolan-5-one derivatives, production thereof and use thereof as growth regulators and/or microbicides
US4483865A (en) * 1981-03-27 1984-11-20 Janssen Pharmaceutica N.V. Antimicrobial imidazole derivatives
DE3145890A1 (de) * 1981-11-19 1983-05-26 Bayer Ag, 5090 Leverkusen Azolylvinyldithioacetale, verfahren zu ihrer herstellung und ihre verwendung als fungizide
US4489087A (en) * 1982-10-13 1984-12-18 Syntex (U.S.A.) Inc. Spermicidal thioketal substituted N-alkyl imidazoles
JPH03115267A (ja) * 1989-09-28 1991-05-16 Maruho Kk プロピオフエノン誘導体、その製造方法、それを含む中枢性筋弛緩剤および抗痙攣剤
AU770359B2 (en) 1999-02-26 2004-02-19 Shell Internationale Research Maatschappij B.V. Liner hanger

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2249616A1 (en) * 1973-10-31 1975-05-30 Pepro Fungicidal compositions contg 1-aralkyl benzimidazoles - for treatment of plants and seeds

Also Published As

Publication number Publication date
DE2860670D1 (en) 1981-08-06
IT7869504A0 (it) 1978-10-31
JPS625143B2 (es) 1987-02-03
EP0001926A1 (en) 1979-05-16
JPS5481269A (en) 1979-06-28
IT1160898B (it) 1987-03-11
EP0001926B1 (en) 1981-04-29

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