ES474973A1 - Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre. - Google Patents
Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre.Info
- Publication number
- ES474973A1 ES474973A1 ES474973A ES474973A ES474973A1 ES 474973 A1 ES474973 A1 ES 474973A1 ES 474973 A ES474973 A ES 474973A ES 474973 A ES474973 A ES 474973A ES 474973 A1 ES474973 A1 ES 474973A1
- Authority
- ES
- Spain
- Prior art keywords
- isoquinoline
- sulfur
- anticonvulsant
- dione
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title abstract 2
- 239000011593 sulfur Substances 0.000 title abstract 2
- 229910052717 sulfur Inorganic materials 0.000 title abstract 2
- VSRVOIDBBCKMTM-UHFFFAOYSA-N 4,4-dimethylisoquinoline-1,3-dione Chemical class C1=CC=C2C(C)(C)C(=O)NC(=O)C2=C1 VSRVOIDBBCKMTM-UHFFFAOYSA-N 0.000 title 1
- 230000001773 anti-convulsant effect Effects 0.000 title 1
- 230000001315 anti-hyperlipaemic effect Effects 0.000 title 1
- 239000001961 anticonvulsive agent Substances 0.000 title 1
- 229960003965 antiepileptics Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000001476 alcoholic effect Effects 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical compound C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000005278 alkyl sulfonyloxy group Chemical group 0.000 abstract 1
- 125000005279 aryl sulfonyloxy group Chemical group 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Procedimiento para la preparación de nuevas isoquinoleindionas que contienen azufre, de la formula general: ***1 en la que A significa un grupo alcohileno inferior y R significa un grupo alcohilo inferior, caracterizado porque se hace reaccionar una 2-alcohil-isiquinoleindiona de la fórmula general: ***2 en la que A es como se ha definido al principio, y Z representa un grupo sobrante activo, tal como un átomo de cloro, bromo o yodo, un grupo alcohilsulfoniloxi o arilsulfoniloxi, con un mercaptano de la fórmula general H ¿ S ¿ R (III) En la que R es como se ha definido al principio, o con su sal de metal alcalino.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772734222 DE2734222A1 (de) | 1977-07-29 | 1977-07-29 | Neue schwefelhaltige isochinolindione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES474973A1 true ES474973A1 (es) | 1979-05-01 |
Family
ID=6015122
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES471492A Expired ES471492A1 (es) | 1977-07-29 | 1978-07-06 | Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre |
| ES474973A Expired ES474973A1 (es) | 1977-07-29 | 1978-11-10 | Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre. |
| ES474974A Expired ES474974A1 (es) | 1977-07-29 | 1978-11-10 | Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES471492A Expired ES471492A1 (es) | 1977-07-29 | 1978-07-06 | Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES474974A Expired ES474974A1 (es) | 1977-07-29 | 1978-11-10 | Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4179508A (es) |
| JP (1) | JPS5427575A (es) |
| AU (1) | AU3845478A (es) |
| BE (1) | BE869366A (es) |
| DE (1) | DE2734222A1 (es) |
| DK (1) | DK335078A (es) |
| ES (3) | ES471492A1 (es) |
| FI (1) | FI782026A7 (es) |
| FR (1) | FR2398735A1 (es) |
| GB (1) | GB2002757A (es) |
| IL (1) | IL55226A0 (es) |
| IT (1) | IT1107655B (es) |
| LU (1) | LU80044A1 (es) |
| NL (1) | NL7808007A (es) |
| NO (1) | NO782590L (es) |
| PT (1) | PT68361A (es) |
| SE (1) | SE7808244L (es) |
| ZA (1) | ZA784289B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230711A (en) * | 1979-01-31 | 1980-10-28 | Chevron Research Company | Fungicidal n-substituted 4,4-dialkyl homophthalimides |
| US4321254A (en) * | 1980-09-26 | 1982-03-23 | Smithkline Corporation | Antiallergic imidodisulfamides |
| JPS62183992A (ja) * | 1986-02-10 | 1987-08-12 | Mitsubishi Heavy Ind Ltd | レ−ザ加工装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3708486A (en) * | 1969-04-17 | 1973-01-02 | Boehringer Sohn Ingelheim | 2-(p-(n'-cycloalkyl-carbamido-n-sulfonyl)-phenethyl)-1,2,3,4-tetrahydro-1,3-dioxo-4,4-dimethyl-isoquinolines and alkali metal salts thereof |
| DE2303483A1 (de) * | 1973-01-25 | 1974-08-01 | Basf Ag | Lactone der benzazaxanthenreihe und farbbildner fuer kopierverfahren |
-
1977
- 1977-07-29 DE DE19772734222 patent/DE2734222A1/de active Pending
-
1978
- 1978-06-26 FI FI782026A patent/FI782026A7/fi not_active Application Discontinuation
- 1978-07-06 ES ES471492A patent/ES471492A1/es not_active Expired
- 1978-07-18 US US05/925,877 patent/US4179508A/en not_active Expired - Lifetime
- 1978-07-20 IT IT50410/78A patent/IT1107655B/it active
- 1978-07-27 DK DK335078A patent/DK335078A/da unknown
- 1978-07-27 LU LU80044A patent/LU80044A1/de unknown
- 1978-07-27 JP JP9099578A patent/JPS5427575A/ja active Pending
- 1978-07-27 IL IL55226A patent/IL55226A0/xx unknown
- 1978-07-28 SE SE7808244A patent/SE7808244L/xx unknown
- 1978-07-28 GB GB7831613A patent/GB2002757A/en not_active Withdrawn
- 1978-07-28 PT PT68361A patent/PT68361A/pt unknown
- 1978-07-28 BE BE189581A patent/BE869366A/xx unknown
- 1978-07-28 FR FR7822498A patent/FR2398735A1/fr not_active Withdrawn
- 1978-07-28 AU AU38454/78A patent/AU3845478A/en active Pending
- 1978-07-28 ZA ZA784289A patent/ZA784289B/xx unknown
- 1978-07-28 NO NO782590A patent/NO782590L/no unknown
- 1978-07-28 NL NL7808007A patent/NL7808007A/xx not_active Application Discontinuation
- 1978-11-10 ES ES474973A patent/ES474973A1/es not_active Expired
- 1978-11-10 ES ES474974A patent/ES474974A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO782590L (no) | 1979-01-30 |
| US4179508A (en) | 1979-12-18 |
| PT68361A (de) | 1978-08-01 |
| IT1107655B (it) | 1985-11-25 |
| DE2734222A1 (de) | 1979-02-15 |
| JPS5427575A (en) | 1979-03-01 |
| FI782026A7 (fi) | 1979-01-30 |
| ZA784289B (en) | 1980-03-26 |
| LU80044A1 (de) | 1979-09-06 |
| BE869366A (fr) | 1979-01-29 |
| AU3845478A (en) | 1980-01-31 |
| NL7808007A (nl) | 1979-01-31 |
| FR2398735A1 (fr) | 1979-02-23 |
| IL55226A0 (en) | 1978-09-29 |
| ES474974A1 (es) | 1979-05-01 |
| DK335078A (da) | 1979-01-30 |
| IT7850410A0 (it) | 1978-07-20 |
| GB2002757A (en) | 1979-02-28 |
| ES471492A1 (es) | 1979-01-16 |
| SE7808244L (sv) | 1979-01-30 |
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