ES477905A1 - Procedure for obtaining an imidazolic derivative. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for obtaining an imidazolic derivative. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES477905A1 ES477905A1 ES477905A ES477905A ES477905A1 ES 477905 A1 ES477905 A1 ES 477905A1 ES 477905 A ES477905 A ES 477905A ES 477905 A ES477905 A ES 477905A ES 477905 A1 ES477905 A1 ES 477905A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- translation
- obtaining
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000000706 filtrate Substances 0.000 abstract 2
- 238000001914 filtration Methods 0.000 abstract 2
- 230000020477 pH reduction Effects 0.000 abstract 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003113 alkalizing effect Effects 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- YWOITFUKFOYODT-UHFFFAOYSA-N methanol;sodium Chemical compound [Na].OC YWOITFUKFOYODT-UHFFFAOYSA-N 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1. Process for obtaining an imidazole derivative of formula i: ** (formula-01) ** characterized by reducing the compound of formula ii: ** (formula-02) ** with an excess of sodium methanol, followed by acidification with a mineral acid, preferably hydrochloric acid, filtration of the formed sodium chloride precipitate, washing thereof with methanol, alkalizing the filtrate with a weak base such as aqueous ammonia, evaporating the solvent to dryness, dissolving in hot ethanol and further reflux, cooling, filtration of the residual salts, concentration of the filtrate, acidification with an ethanol solution of hydrogen chloride, addition of an equal volume of acetone and crystallization. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES477905A ES477905A1 (en) | 1979-02-07 | 1979-02-07 | Procedure for obtaining an imidazolic derivative. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES477905A ES477905A1 (en) | 1979-02-07 | 1979-02-07 | Procedure for obtaining an imidazolic derivative. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES477905A1 true ES477905A1 (en) | 1980-07-01 |
Family
ID=8477679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES477905A Expired ES477905A1 (en) | 1979-02-07 | 1979-02-07 | Procedure for obtaining an imidazolic derivative. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES477905A1 (en) |
-
1979
- 1979-02-07 ES ES477905A patent/ES477905A1/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES477741A1 (en) | A procedure for preparing acetic acid derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES382550A1 (en) | 2-(aminoalkyl-amino)-4-amino thieno(3,2-d)pyrimidines | |
| ES477905A1 (en) | Procedure for obtaining an imidazolic derivative. (Machine-translation by Google Translate, not legally binding) | |
| ES371373A1 (en) | Procedure for the obtaining of substitute 4-oxo-3-amino-3,4-dihydrotean (3,2-d) pyrimidine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES296634A1 (en) | Procedure for the production of new heterocyclic compounds (Machine-translation by Google Translate, not legally binding) | |
| ES385091A1 (en) | Beta-(2,4,6-triiodo-3-acetamidinophenyl)-propionic acids | |
| ES454005A1 (en) | Triazole derivatives and processes for the production thereof | |
| ES406768A1 (en) | Procedure for the preparation of new indol derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES461157A1 (en) | Bicyclomycin derivatives | |
| ES426949A1 (en) | Procedure for the preparation of new 1,4-benzodiazepinas. (Machine-translation by Google Translate, not legally binding) | |
| ES397708A1 (en) | Procedure for the obtaining derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding) | |
| ES431811A1 (en) | Procedure for the preparation of derivatives of hydroxocobalamine and amino acids. (Machine-translation by Google Translate, not legally binding) | |
| ES311820A1 (en) | Procedure for the production of indollic derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES382147A1 (en) | A procedure for preparing N-substituted morpholine compounds. (Machine-translation by Google Translate, not legally binding) | |
| ES383342A1 (en) | P-carbamoylethylphenylsulfonyl derivatives | |
| ES470378A1 (en) | Procedure for preparing methylamine derivatives (Machine-translation by Google Translate, not legally binding) | |
| ES416973A1 (en) | Procedure for the preparation of derivatives of 1,8-naftiridina. (Machine-translation by Google Translate, not legally binding) | |
| ES314469A1 (en) | Procedure for preparing new theophylline derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES384599A1 (en) | Procedure for the preparation of new basic pirrol derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES427622A1 (en) | Procedure for the preparation of 2-amino-bencil-amines. (Machine-translation by Google Translate, not legally binding) | |
| ES358392A2 (en) | A procedure for preparing benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES411749A1 (en) | Novel steroid ester | |
| ES385062A1 (en) | Derivatives of 1-amino-3-phenoxy-propan-2-ol, and processes for preparing them | |
| ES401633A1 (en) | Procedure for the obtaining of substitute 4-oxo-3-amino-3,4-dihydrotean (3,2-d) pyrimidine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES302770A1 (en) | PROCEDURE FOR THE PRODUCTION OF HETEROCYCLIC COMPOUNDS |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970203 |