ES479446A1 - Un metodo de producir derivados de bencimidazol. - Google Patents

Un metodo de producir derivados de bencimidazol.

Info

Publication number: ES479446A1
Authority: ES; Spain
Prior art keywords: substituted; aryl; heterocyclic group; benzyl; alkyl
Prior art date: 1978-04-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES479446A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mundipharma AG

Original Assignee

Mundipharma AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-04-10

Filing date

1979-04-09

Publication date

1979-08-01

1979-04-09 Application filed by Mundipharma AG filed Critical Mundipharma AG

1979-08-01 Publication of ES479446A1 publication Critical patent/ES479446A1/es

Status Expired legal-status Critical Current

Links

BASPJMOEXODOEJ-UHFFFAOYSA-N 3h-benzimidazole-5-sulfonamide Chemical class NS(=O)(=O)C1=CC=C2NC=NC2=C1 BASPJMOEXODOEJ-UHFFFAOYSA-N 0.000 title 1
MXMZCLLIUQEKSN-UHFFFAOYSA-N benzimidazoline Chemical class C1=CC=C2NCNC2=C1 MXMZCLLIUQEKSN-UHFFFAOYSA-N 0.000 title 1
125000000623 heterocyclic group Chemical group 0.000 abstract 6
125000003118 aryl group Chemical group 0.000 abstract 4
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 4
125000003107 substituted aryl group Chemical group 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
QUVNDNJVCZLXNI-UHFFFAOYSA-N N=1C=2C=C(Cl)C(S(=O)(=O)N)=CC=2NC=1N1C(=O)C1=O Chemical compound N=1C=2C=C(Cl)C(S(=O)(=O)N)=CC=2NC=1N1C(=O)C1=O QUVNDNJVCZLXNI-UHFFFAOYSA-N 0.000 abstract 1
-1 amino, substituted amino, guanidino, substituted guanidino Chemical group 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000002934 diuretic Substances 0.000 abstract 1
230000001882 diuretic effect Effects 0.000 abstract 1
FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 abstract 1
229940124530 sulfonamide Drugs 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ES479446A 1978-04-10 1979-04-09 Un metodo de producir derivados de bencimidazol. Expired ES479446A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US89504878A	1978-04-10	1978-04-10

Publications (1)

Publication Number	Publication Date
ES479446A1 true ES479446A1 (es)	1979-08-01

Family

ID=25403870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES479446A Expired ES479446A1 (es)	1978-04-10	1979-04-09	Un metodo de producir derivados de bencimidazol.

Country Status (19)

Country	Link
JP (1)	JPS54138561A (fr)
AT (1)	AT372951B (fr)
AU (1)	AU531086B2 (fr)
BE (1)	BE875425A (fr)
CA (1)	CA1126280A (fr)
DE (1)	DE2914084A1 (fr)
DK (1)	DK139079A (fr)
ES (1)	ES479446A1 (fr)
FI (1)	FI74461C (fr)
FR (1)	FR2422644A1 (fr)
GB (1)	GB2018766B (fr)
GR (1)	GR68483B (fr)
IL (1)	IL57105A (fr)
IT (1)	IT1193755B (fr)
NL (1)	NL7902802A (fr)
NZ (1)	NZ190136A (fr)
PT (1)	PT69458A (fr)
SE (1)	SE446532B (fr)
ZA (1)	ZA791726B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102070466A (zh) *	2010-12-28	2011-05-25	天津市筠凯化工科技有限公司	5-氯-2-硝基苯胺制备方法
CN108558712A (zh) *	2018-06-20	2018-09-21	新乡市锦源化工有限公司	一种以乙酰苯胺为原料合成高纯度对氨基苯磺酰胺的方法及对氨基苯磺酰胺
CN110305018B (zh) *	2019-06-06	2022-07-15	浙江普洛家园药业有限公司	一种3-溴-2-氟硝基苯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH404675A (de) *	1961-06-29	1965-12-31	Siegfried Ag	Verfahren zur Herstellung neuer heterocyclischer Sulfonamidoverbindungen
FR1469504A (fr) *	1964-10-22	1967-02-17	Fisons Pest Control Ltd	Composés insecticides
FR1477792A (fr) *	1965-03-24	1967-04-21	Fisons Pest Control Ltd	Nouveaux benzimidazoles
GB1163711A (en) *	1966-01-13	1969-09-10	Fisons Pest Control Ltd	Substituted Benzimidazoles and Biocidally-Active Compositions
GB1356244A (en) *	1970-07-29	1974-06-12	Fisons Ltd	Substituted benzimidazole parasiticides

1979
- 1979-03-26 CA CA324,146A patent/CA1126280A/fr not_active Expired
- 1979-04-02 FI FI791083A patent/FI74461C/fi not_active IP Right Cessation
- 1979-04-02 SE SE7902911A patent/SE446532B/sv not_active IP Right Cessation
- 1979-04-02 AU AU45675/79A patent/AU531086B2/en not_active Ceased
- 1979-04-03 GR GR58771A patent/GR68483B/el unknown
- 1979-04-04 DK DK139079A patent/DK139079A/da not_active IP Right Cessation
- 1979-04-06 GB GB7912255A patent/GB2018766B/en not_active Expired
- 1979-04-07 DE DE19792914084 patent/DE2914084A1/de not_active Withdrawn
- 1979-04-09 AT AT0263379A patent/AT372951B/de not_active IP Right Cessation
- 1979-04-09 FR FR7908945A patent/FR2422644A1/fr active Granted
- 1979-04-09 BE BE0/194480A patent/BE875425A/fr not_active IP Right Cessation
- 1979-04-09 NZ NZ190136A patent/NZ190136A/xx unknown
- 1979-04-09 ES ES479446A patent/ES479446A1/es not_active Expired
- 1979-04-09 PT PT69458A patent/PT69458A/pt unknown
- 1979-04-09 JP JP4211979A patent/JPS54138561A/ja active Granted
- 1979-04-10 ZA ZA791726A patent/ZA791726B/xx unknown
- 1979-04-10 IT IT48686/79A patent/IT1193755B/it active
- 1979-04-10 NL NL7902802A patent/NL7902802A/xx not_active Application Discontinuation
- 1979-04-22 IL IL57105A patent/IL57105A/xx unknown

Also Published As

Publication number	Publication date
NZ190136A (en)	1982-11-23
JPH0250904B2 (fr)	1990-11-05
GB2018766B (en)	1982-09-22
CA1126280A (fr)	1982-06-22
IT7948686A0 (it)	1979-04-10
ZA791726B (en)	1980-05-28
FI74461C (fi)	1988-02-08
ATA263379A (de)	1983-04-15
AU4567579A (en)	1979-10-18
NL7902802A (nl)	1979-10-12
GR68483B (fr)	1982-01-04
IT1193755B (it)	1988-08-24
FI791083A7 (fi)	1979-10-11
DK139079A (da)	1979-10-11
SE7902911L (sv)	1979-10-11
PT69458A (en)	1979-05-01
IL57105A (en)	1983-10-31
SE446532B (sv)	1986-09-22
FR2422644A1 (fr)	1979-11-09
GB2018766A (en)	1979-10-24
JPS54138561A (en)	1979-10-27
AU531086B2 (en)	1983-08-11
DE2914084A1 (de)	1979-10-25
FI74461B (fi)	1987-10-30
AT372951B (de)	1983-12-12
BE875425A (fr)	1979-07-31
FR2422644B1 (fr)	1982-12-17
IL57105A0 (en)	1979-07-25

Publication	Publication Date	Title
ES8305334A1 (es)	1983-04-01	Derivados de carbostirilo y sus sales.
ES520300A0 (es)	1983-12-01	Procedimiento para la obtencion de 1,4-dihidropiridinas.
CA2147056A1 (fr)	1995-10-19	Amides d'acide delta-amino-gamma-hydroxy-omega-arylalcanoique
DE69620443D1 (de)	2002-05-08	Naphthyl substituierte benzimidazolderivate als antikoagulantien
ES2097174T3 (es)	1997-04-01	Derivados de la 2-ciclohexan-1-il amina.
ES2067500T3 (es)	1995-04-01	1-indolilalquil-4-(piridinil-sustituidas)piperazinas.
ES465384A1 (es)	1979-01-01	Procedimiento para la obtencion de ciclopentan-1-aminas
DE69027235D1 (de)	1996-07-11	Xanthinderivate
ES8101564A1 (es)	1980-12-16	Un procedimiento para la preparacion de nuevos derivados he-terociclicos
TR199902069T2 (xx)	2000-05-22	Sikloimido ikameli benzo yap�s�nda kayna�t�r�lm�� heterosiklik herbisitler.
DE3671443D1 (de)	1990-06-28	5-acylamido-1-aryl-pyrazole.
CO4340623A1 (es)	1996-07-30	Derivados de indolina, metodo de preparacion y uso
ES8500247A1 (es)	1984-10-01	Un procedimiento para la preparacion de un isomero optico en su forma (-) de un derivado de triazina.
TR199901381A2 (xx)	2000-01-21	Diaza-spiro$3,5]nonan t�revleri.
AU569787B2 (en)	1988-02-18	Tetrahydrothienopyridines
DK0777653T3 (da)	2001-10-08	Dihydropyridinderivater som bradykininantagonister
GB2018766A (en)	1979-10-24	6-Sulphamyl benzimidazoles and benzimidazolidines
YU47564B (sh)	1995-10-03	Triazolilhidrazidni derivati i postupak za njihovo pravljenje
NO994104D0 (no)	1999-08-25	5-hydroksymetyl-2-aminotetraliner i form av kardiovaskulaere midler
ES8604219A1 (es)	1986-01-16	Un procedimiento para la preparacion de benzoquinolicinas
ES8105309A1 (es)	1981-05-16	Un procedimiento para la preparacion de nuevos derivados de cromano.
YU165185A (sh)	1992-09-07	Novialfa-aminoalkil-alfa-alkilfenilaceton itrili
ES8701729A1 (es)	1986-12-16	Procedimiento de preparacion de nuevos derivados de la 8-alcoxicarbonilamino-isoquinolina y de sus sales de adicion acida
KR970706280A (ko)	1997-11-03	5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists)
EP0486687A4 (en)	1992-06-17	Quinolonecarboxylic acid derivatives