ES481225A1 - Procedimiento para la preparacion de un medicamento con efecto antivirico que contiene acido ribonucleico de transferen-cia. - Google Patents

Procedimiento para la preparacion de un medicamento con efecto antivirico que contiene acido ribonucleico de transferen-cia.

Info

Publication number
ES481225A1
ES481225A1 ES481225A ES481225A ES481225A1 ES 481225 A1 ES481225 A1 ES 481225A1 ES 481225 A ES481225 A ES 481225A ES 481225 A ES481225 A ES 481225A ES 481225 A1 ES481225 A1 ES 481225A1
Authority
ES
Spain
Prior art keywords
ribonucleic acid
transfer
compositions containing
precipitate
antiviral compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481225A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES481225A1 publication Critical patent/ES481225A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Procedimiento para la preparación de un medicamento con efecto antivírico que contiene ácido ribonucleico de transferencia, caracterizado porque se trata levadura con fenol, se sifona la fase acuosa y se somete ésta a una precipitación con etanol, después de lo cual se purifica el precipitado de ácido ribonucleico de transferencia eurariótico por medio de dietilaminoetil-celulosa, se mezcla este precipitado con sustancias auxiliares, excipientes y/o aditivas farmacéuticas usuales y se lleva la mezcla a una forma adecuada para su aplicación nasal, tópica o intraperitoneal.
ES481225A 1978-06-03 1979-06-02 Procedimiento para la preparacion de un medicamento con efecto antivirico que contiene acido ribonucleico de transferen-cia. Expired ES481225A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782824411 DE2824411A1 (de) 1978-06-03 1978-06-03 Antiviral wirksame t-rna-praeparate

Publications (1)

Publication Number Publication Date
ES481225A1 true ES481225A1 (es) 1980-08-16

Family

ID=6040941

Family Applications (1)

Application Number Title Priority Date Filing Date
ES481225A Expired ES481225A1 (es) 1978-06-03 1979-06-02 Procedimiento para la preparacion de un medicamento con efecto antivirico que contiene acido ribonucleico de transferen-cia.

Country Status (16)

Country Link
US (1) US4213970A (es)
JP (1) JPS54160746A (es)
AT (1) AT367770B (es)
AU (1) AU526125B2 (es)
BE (1) BE876739A (es)
DE (1) DE2824411A1 (es)
DK (1) DK230679A (es)
ES (1) ES481225A1 (es)
FI (1) FI791774A7 (es)
FR (1) FR2427098A1 (es)
GB (1) GB2022412B (es)
IE (1) IE48155B1 (es)
IT (1) IT1117170B (es)
LU (1) LU81348A1 (es)
NL (1) NL7904340A (es)
SE (1) SE7904840L (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834443A (en) * 1996-05-21 1998-11-10 Masiello; Domenick J. Composition and method for treating herpes simplex
LT4475B (lt) * 1997-02-28 1999-02-25 Virmantas Stunžėnas Informacinės ribonukleino rūgšties panaudojimas vaistinėse medžiagose, skirtose padidinti šios ribonukleino rūgšties koduojamo baltymo kiekį paciento ląstelėse
WO2000027340A2 (en) * 1998-11-12 2000-05-18 The Children's Medical Center Corporation USE OF t-RNA AND FRAGMENTS FOR INHIBITING ANGIOGENESIS AND COMPOSITIONS THEREOF
DE19940748A1 (de) * 1999-08-27 2001-03-01 Hugo Seinfeld Arzneimittel enthaltend xenogene Oligo- oder/und Polyribonukleotide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR4269M (es) * 1964-12-09 1966-07-11
US3389133A (en) * 1966-08-10 1968-06-18 Schwarz Biores Inc Process for isolating and purifying soluble ribonucleic acid
BE757291A (fr) * 1969-10-10 1971-04-09 Smith Kline French Lab Complexe antiviral de arn et d'un polysaccharide
BE757653A (fr) * 1969-10-21 1971-04-16 Ugine Kuhlmann Nouveaux medicaments derives d'acides nucleiques et procedes pour leur preparation
GB1300567A (en) * 1969-12-20 1972-12-20 Beecham Group Ltd Therapeutic compositions
DE2034118A1 (en) * 1970-07-09 1972-01-13 Seinfeld, Hugo, Brendel, Walter, Prof Dr . 8000 München Xenogenic nucleic acids for enhancing antigenicity - of peptides and proteins
US4124702A (en) * 1971-07-06 1978-11-07 Merck & Co., Inc. Polynucleotides active as inducers of interferon production in living animal cells
US3966707A (en) * 1971-11-26 1976-06-29 Beecham Group Limited Process for preparing double stranded RNA

Also Published As

Publication number Publication date
FR2427098A1 (fr) 1979-12-28
ATA357579A (de) 1981-12-15
BE876739A (fr) 1979-12-03
AT367770B (de) 1982-07-26
NL7904340A (nl) 1979-12-05
SE7904840L (sv) 1979-12-04
IT1117170B (it) 1986-02-17
DK230679A (da) 1979-12-04
IT7949268A0 (it) 1979-06-01
FR2427098B1 (es) 1984-02-24
JPS54160746A (en) 1979-12-19
DE2824411A1 (de) 1979-12-13
AU4769679A (en) 1979-12-13
IE791084L (en) 1979-11-12
IE48155B1 (en) 1984-10-17
GB2022412A (en) 1979-12-19
LU81348A1 (de) 1980-12-16
US4213970A (en) 1980-07-22
FI791774A7 (fi) 1979-12-04
GB2022412B (en) 1982-12-22
AU526125B2 (en) 1982-12-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601