ES483374A1 - Procedimiento para modificar las propiedades antigenas de unantigeno de polen de la hierba - Google Patents
Procedimiento para modificar las propiedades antigenas de unantigeno de polen de la hierbaInfo
- Publication number
- ES483374A1 ES483374A1 ES483374A ES483374A ES483374A1 ES 483374 A1 ES483374 A1 ES 483374A1 ES 483374 A ES483374 A ES 483374A ES 483374 A ES483374 A ES 483374A ES 483374 A1 ES483374 A1 ES 483374A1
- Authority
- ES
- Spain
- Prior art keywords
- grass pollen
- antigen
- modified
- antigens
- cleavage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nonmetallic Welding Materials (AREA)
- Cosmetics (AREA)
Abstract
Procedimiento para modificar las propiedades antígenas de un antígeno de polen de la hierba, que contiene una mitad de cuercitina, o un fragmento del mismo que tiene la estructura: **(Fórmula)** en la que G representa glucosa, y T representa treonina o un péptido enlazado a dicha estructura a través de una molécula de treonina, caracterizado porque comprende someter dicho antígeno a condiciones oxidantes de modo que dichos anillos dihidroxi aromáticos sufran reagrupamiento y escisión de anillo para dar un producto sustancialmente libre de propiedades antígenas pero capaz de activar células T e inducir células Ts.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/933,907 US4215036A (en) | 1978-08-15 | 1978-08-15 | Modified grass pollen antigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES483374A1 true ES483374A1 (es) | 1980-04-16 |
Family
ID=25464673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES483374A Expired ES483374A1 (es) | 1978-08-15 | 1979-08-14 | Procedimiento para modificar las propiedades antigenas de unantigeno de polen de la hierba |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4215036A (es) |
| JP (1) | JPS5551026A (es) |
| AU (1) | AU526205B2 (es) |
| BE (1) | BE878197A (es) |
| CA (1) | CA1137078A (es) |
| DE (1) | DE2932604A1 (es) |
| DK (1) | DK337479A (es) |
| ES (1) | ES483374A1 (es) |
| FI (1) | FI792430A7 (es) |
| FR (1) | FR2433341A1 (es) |
| GB (1) | GB2031433B (es) |
| NL (1) | NL7906183A (es) |
| NO (1) | NO792643L (es) |
| SE (1) | SE7906793L (es) |
| ZA (1) | ZA794060B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0038154B1 (en) * | 1980-04-15 | 1983-09-21 | Beecham Group Plc | Allergens modified with polysarcosines |
| SE8303401D0 (sv) * | 1983-06-15 | 1983-06-15 | Pharmacia Ab | Beredning och dess anvendning |
| US4880635B1 (en) * | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
| JPS62162963A (ja) * | 1986-01-10 | 1987-07-18 | Sadao Shiosaka | 金属コロイド粒子を担体とする低分子物質に対する特異抗体の作成法 |
| US4990336A (en) * | 1989-02-08 | 1991-02-05 | Biosearch, Inc. | Sustained release dosage form |
| US5126147A (en) * | 1990-02-08 | 1992-06-30 | Biosearch, Inc. | Sustained release dosage form |
| US6274552B1 (en) | 1993-03-18 | 2001-08-14 | Cytimmune Sciences, Inc. | Composition and method for delivery of biologically-active factors |
| ZA946765B (en) * | 1993-09-02 | 1996-02-15 | Dartmouth College | Methods of prolonged suppression of humoral immunity |
| US20010055581A1 (en) * | 1994-03-18 | 2001-12-27 | Lawrence Tamarkin | Composition and method for delivery of biologically-active factors |
| US7229841B2 (en) * | 2001-04-30 | 2007-06-12 | Cytimmune Sciences, Inc. | Colloidal metal compositions and methods |
| US6407218B1 (en) | 1997-11-10 | 2002-06-18 | Cytimmune Sciences, Inc. | Method and compositions for enhancing immune response and for the production of in vitro mabs |
| DE602004032025D1 (de) * | 2003-06-23 | 2011-05-12 | Biotech Tools Sa | Epitop-zusammensetzung zur enterischen verabreichung hergestellt durch hydrolyse von antigenen strukturen mit chymotrypsin |
| US20050175583A1 (en) * | 2003-12-02 | 2005-08-11 | Lawrence Tamarkin | Methods and compositions for the production of monoclonal antibodies |
| EP1715971A4 (en) * | 2004-01-28 | 2010-10-13 | Cytimmune Sciences Inc | FUNCTIONALIZED COLLOIDAL METAL COMPOSITIONS AND METHODS |
| US20110014118A1 (en) * | 2007-09-21 | 2011-01-20 | Lawrence Tamarkin | Nanotherapeutic colloidal metal compositions and methods |
| KR20100123674A (ko) * | 2007-09-21 | 2010-11-24 | 싸이티뮨 사이언스, 인크. | 나노치료제 콜로이드성 금속 조성물 및 방법 |
| CA2706700A1 (en) | 2007-11-08 | 2009-05-14 | Cytimmune Sciences, Inc. | Compositions and methods for generating antibodies |
-
1978
- 1978-08-15 US US05/933,907 patent/US4215036A/en not_active Expired - Lifetime
-
1979
- 1979-08-03 FI FI792430A patent/FI792430A7/fi not_active Application Discontinuation
- 1979-08-06 ZA ZA00794060A patent/ZA794060B/xx unknown
- 1979-08-07 GB GB7927437A patent/GB2031433B/en not_active Expired
- 1979-08-07 AU AU49632/79A patent/AU526205B2/en not_active Ceased
- 1979-08-10 DE DE19792932604 patent/DE2932604A1/de not_active Withdrawn
- 1979-08-10 BE BE0/196694A patent/BE878197A/xx unknown
- 1979-08-10 FR FR7920510A patent/FR2433341A1/fr active Granted
- 1979-08-13 DK DK337479A patent/DK337479A/da not_active Application Discontinuation
- 1979-08-14 CA CA000333758A patent/CA1137078A/en not_active Expired
- 1979-08-14 ES ES483374A patent/ES483374A1/es not_active Expired
- 1979-08-14 SE SE7906793A patent/SE7906793L/xx not_active Application Discontinuation
- 1979-08-14 NO NO792643A patent/NO792643L/no unknown
- 1979-08-14 NL NL7906183A patent/NL7906183A/nl not_active Application Discontinuation
- 1979-08-15 JP JP10395179A patent/JPS5551026A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5551026A (en) | 1980-04-14 |
| AU526205B2 (en) | 1982-12-23 |
| DK337479A (da) | 1980-02-16 |
| FR2433341B1 (es) | 1983-03-11 |
| US4215036A (en) | 1980-07-29 |
| DE2932604A1 (de) | 1980-02-28 |
| ZA794060B (en) | 1980-08-27 |
| NL7906183A (nl) | 1980-02-19 |
| FI792430A7 (fi) | 1981-01-01 |
| FR2433341A1 (fr) | 1980-03-14 |
| AU4963279A (en) | 1980-02-21 |
| GB2031433A (en) | 1980-04-23 |
| SE7906793L (sv) | 1980-02-16 |
| BE878197A (fr) | 1979-12-03 |
| CA1137078A (en) | 1982-12-07 |
| GB2031433B (en) | 1982-10-13 |
| NO792643L (no) | 1980-02-18 |
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