ES483977A1 - Procedimiento para la obtencion de derivados de acido hidroxiacetico - Google Patents

Procedimiento para la obtencion de derivados de acido hidroxiacetico

Info

Publication number
ES483977A1
ES483977A1 ES483977A ES483977A ES483977A1 ES 483977 A1 ES483977 A1 ES 483977A1 ES 483977 A ES483977 A ES 483977A ES 483977 A ES483977 A ES 483977A ES 483977 A1 ES483977 A1 ES 483977A1
Authority
ES
Spain
Prior art keywords
acid derivatives
arthritic
hydroxyacetic acid
manufacture
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES483977A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES483977A1 publication Critical patent/ES483977A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procedimiento para preparar derivados del ácido hidroxiacético y, más particularmente, para preparar derivados del ácido hidroxiacético que poseen propiedades antiartríticas útiles en el tratamiento de las enfermedades de las articulaciones artríticas. Es sabido que diversos ácidos 2-(benciloxi sustituido)acéticos y sus derivados 2-trifluorometilo hacen descender el nivel de por lo menos un factor que se cree está comprendido en la enfermedad ateroesclerótica, por ejemplo del nivel del colesterol en el suero, de los triglicéridos en el suero y del fibrinógeno en el plasma, y, en determinados casos, también poseen propiedades artiartríticas. También es sabido que diversos derivados del ácido 2-(fenoxi)fenilacético poseen propiedades hipocolesterolémicas.
ES483977A 1978-09-08 1979-09-07 Procedimiento para la obtencion de derivados de acido hidroxiacetico Expired ES483977A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7836173 1978-09-08

Publications (1)

Publication Number Publication Date
ES483977A1 true ES483977A1 (es) 1980-04-16

Family

ID=10499548

Family Applications (2)

Application Number Title Priority Date Filing Date
ES483978A Expired ES483978A1 (es) 1978-09-08 1979-09-07 Procedimiento para la obtencion de derivados de acido hidro-xialcanoico
ES483977A Expired ES483977A1 (es) 1978-09-08 1979-09-07 Procedimiento para la obtencion de derivados de acido hidroxiacetico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES483978A Expired ES483978A1 (es) 1978-09-08 1979-09-07 Procedimiento para la obtencion de derivados de acido hidro-xialcanoico

Country Status (27)

Country Link
US (2) US4310544A (es)
EP (1) EP0009306B1 (es)
JP (2) JPS5538385A (es)
AT (1) ATE1855T1 (es)
AU (1) AU522183B2 (es)
BE (2) BE878594A (es)
CA (1) CA1142542A (es)
CS (1) CS212244B2 (es)
DD (1) DD145747A5 (es)
DE (3) DE2964097D1 (es)
DK (1) DK369579A (es)
ES (2) ES483978A1 (es)
FI (1) FI792564A7 (es)
FR (2) FR2468574A1 (es)
GB (1) GB2031406B (es)
GR (1) GR65651B (es)
IE (1) IE48791B1 (es)
IL (1) IL58074A (es)
IT (1) IT1122501B (es)
NL (2) NL7906339A (es)
NO (1) NO792589L (es)
PH (1) PH14631A (es)
PL (2) PL124197B1 (es)
PT (1) PT70146A (es)
SE (2) SE7907311L (es)
ZA (1) ZA794088B (es)
ZW (1) ZW15179A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2073178B (en) * 1980-04-03 1984-01-25 Ici Ltd Dioxolane derivatives
FR2514355A1 (fr) * 1981-10-14 1983-04-15 Fabre Sa Pierre Derives de biphenyl alcoyl carboxylates, leur procede de preparation et leur utilisation comme medicaments
HRP950558A2 (en) * 1994-11-15 1997-12-31 Scott M. Wilhelm Substituted 4-biarylbutric or biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
AU4154799A (en) * 1998-06-02 1999-12-20 Arthromics Plc Compounds which interact with the thyroid hormone receptor for the treatment of fibrotic disease
US8742167B2 (en) * 2008-01-11 2014-06-03 Shanghai Institute Of Pharmaceutical Industry Therapeutic formulations based on asiatic acid and selected salts thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB112107A (en) 1917-08-03 1917-12-27 Theophile Louche Improvements in Wooden Soles for Shoes.
GB140246A (en) 1919-05-03 1920-03-25 Herbert Mills Parsons Improvements in and relating to air suction and the like chambers in dental palates
US3378582A (en) 1964-03-20 1968-04-16 Merck & Co Inc (alpha-phenoxy)-and (alpha-phenylthio)-omegaphenyl-alkanoic acids
GB1121027A (en) 1966-06-23 1968-07-24 Ici Ltd New carboxylic acid derivatives, processes for the preparation thereof and compositions containing the same
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
BE786644A (fr) 1971-07-23 1973-01-24 Hoechst Ag Derives d'acides phenoxy-4 phenoxy-alcane-carboxyliques leur preparation et les medicaments qui en contiennent
DE2358789A1 (de) * 1973-02-07 1975-06-05 Merck Patent Gmbh Hydratropasaeure-derivate und verfahren zu ihrer herstellung
GB1499508A (en) 1974-12-06 1978-02-01 Ici Ltd 3,3,3-trifluoropropionic acid derivatives

Also Published As

Publication number Publication date
NO792589L (no) 1980-03-11
FI792564A7 (fi) 1981-01-01
ES483978A1 (es) 1980-04-16
CS212244B2 (en) 1982-03-26
CA1142542A (en) 1983-03-08
DE2934398A1 (de) 1980-06-12
IT1122501B (it) 1986-04-23
AU522183B2 (en) 1982-05-20
AU4975379A (en) 1980-03-13
NL7906554A (nl) 1980-03-11
IT7925221A0 (it) 1979-08-21
JPS5538384A (en) 1980-03-17
PL124197B1 (en) 1982-12-31
IE48791B1 (en) 1985-05-15
DE2964097D1 (en) 1982-12-30
EP0009306A1 (en) 1980-04-02
PL117130B1 (en) 1981-07-31
FR2468574B1 (es) 1983-04-22
GB2031406A (en) 1980-04-23
JPS5538385A (en) 1980-03-17
IL58074A (en) 1982-07-30
US4310544A (en) 1982-01-12
ZW15179A1 (en) 1981-03-18
PT70146A (en) 1979-10-01
SE437262B (sv) 1985-02-18
DE2934375A1 (de) 1980-06-12
PH14631A (en) 1981-10-12
SE7907311L (sv) 1980-03-09
FR2468575B1 (es) 1983-02-18
IL58074A0 (en) 1979-12-30
GB2031406B (en) 1982-06-16
DK369579A (da) 1980-03-09
NL7906339A (nl) 1980-03-11
DD145747A5 (de) 1981-01-07
IE791510L (en) 1980-03-08
FR2468575A1 (fr) 1981-05-08
SE7907390L (sv) 1980-03-09
ZA794088B (en) 1980-08-27
FR2468574A1 (fr) 1981-05-08
BE878595A (fr) 1980-03-04
BE878594A (fr) 1980-03-04
EP0009306B1 (en) 1982-11-24
GR65651B (en) 1980-10-16
PL217978A1 (es) 1980-04-21
ATE1855T1 (de) 1982-12-15
US4304788A (en) 1981-12-08

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