ES486782A0 - Un procedimiento para la preparacion de derivados de imida- zol. - Google Patents

Un procedimiento para la preparacion de derivados de imida- zol.

Info

Publication number
ES486782A0
ES486782A0 ES486782A ES486782A ES486782A0 ES 486782 A0 ES486782 A0 ES 486782A0 ES 486782 A ES486782 A ES 486782A ES 486782 A ES486782 A ES 486782A ES 486782 A0 ES486782 A0 ES 486782A0
Authority
ES
Spain
Prior art keywords
imida
zol
derivatives
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES486782A
Other languages
English (en)
Other versions
ES8101556A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10501705&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES486782(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Publication of ES486782A0 publication Critical patent/ES486782A0/es
Publication of ES8101556A1 publication Critical patent/ES8101556A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES486782A 1978-12-13 1979-12-11 Un procedimiento para la preparacion de derivados de imida- zol. Expired ES8101556A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7848367 1978-12-13

Publications (2)

Publication Number Publication Date
ES486782A0 true ES486782A0 (es) 1980-12-16
ES8101556A1 ES8101556A1 (es) 1980-12-16

Family

ID=10501705

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486782A Expired ES8101556A1 (es) 1978-12-13 1979-12-11 Un procedimiento para la preparacion de derivados de imida- zol.

Country Status (34)

Country Link
US (2) US4602016A (es)
JP (1) JPS585197B2 (es)
KR (1) KR830001243B1 (es)
AR (1) AR227637A1 (es)
AT (1) AT373879B (es)
AU (1) AU517892B2 (es)
BE (1) BE880584A (es)
CA (1) CA1108137A (es)
CH (1) CH644597A5 (es)
CS (1) CS216517B2 (es)
DD (1) DD147943A5 (es)
DE (1) DE2950019A1 (es)
DK (1) DK471479A (es)
EG (1) EG14227A (es)
ES (1) ES8101556A1 (es)
FI (1) FI70888C (es)
FR (1) FR2444031A1 (es)
GB (1) GB2038821B (es)
GR (1) GR73003B (es)
HU (1) HU183016B (es)
IE (1) IE49318B1 (es)
IL (1) IL58917A (es)
IT (1) IT1194900B (es)
LU (1) LU81985A1 (es)
NL (1) NL177749C (es)
NO (1) NO153135C (es)
NZ (1) NZ192360A (es)
PH (1) PH15056A (es)
PL (1) PL134005B1 (es)
PT (1) PT70571A (es)
SE (1) SE444937B (es)
SU (1) SU878195A3 (es)
YU (1) YU301879A (es)
ZA (1) ZA796708B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350696A (en) * 1980-03-08 1982-09-21 Pfizer Inc. Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof
US4444775A (en) * 1981-06-22 1984-04-24 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridines
DE3148291A1 (de) * 1981-12-05 1983-06-09 Basf Ag, 6700 Ludwigshafen Harnstoffderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
JPS58113178A (ja) * 1981-12-28 1983-07-05 Yamanouchi Pharmaceut Co Ltd 「お」−(1−イミダゾリル)アルキルオキシ(またはチオ)ベンゼン誘導体
US4588732A (en) * 1982-12-21 1986-05-13 Ciba-Geigy Corporation Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors
US4470986A (en) * 1982-12-21 1984-09-11 Ciba-Geigy Corporation Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
NL8301550A (nl) * 1983-05-03 1984-12-03 Gist Brocades Nv Imidazolethanol esters.
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
PH22076A (en) * 1983-08-25 1988-05-20 Daiichi Seiyaku Co Benzocycloalkane derivative
IT1212791B (it) * 1983-11-24 1989-11-30 Medea Res Srl Derivato imidazolico adattivita' vasodilatatrice ed antitrombotica, sua preparazione e composizioni farmaceutiche che lo contengono.
ES8601148A1 (es) * 1984-12-10 1985-11-16 Ferrer Int Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos.
JPH0625141B2 (ja) * 1985-01-16 1994-04-06 三共株式会社 イミダゾ−ル誘導体およびその製法
NO166644C (no) 1986-01-28 1991-08-21 Sankyo Co Analogifremgangsmaate til fremstilling av tianaftenderivater.
ATE90076T1 (de) 1986-03-27 1993-06-15 Merck Frosst Canada Inc Tetrahydrocarbazole ester.
JPS63179840A (ja) * 1986-07-24 1988-07-23 Yamanouchi Pharmaceut Co Ltd 新規化学物質
DE3860908D1 (de) * 1987-04-03 1990-12-06 Cl Pharma Neue 2-thienyloxyessigsaeurederivate, ein verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
JPH01125372A (ja) * 1988-09-12 1989-05-17 Yamanouchi Pharmaceut Co Ltd イミダゾリルアルキルオキシベンゼン誘導体
DE4204686A1 (de) * 1992-02-17 1993-08-19 Gruenenthal Gmbh Imidazolylphenolderivate, diese enthaltende arzneimittel sowie ein verfahren zur herstellung dieser verbindungen und arzneimitteln
ES2201104T3 (es) * 1994-04-26 2004-03-16 Roche Palo Alto Llc Derivados de benzociclohexilimidazoltiona.
AU2890899A (en) * 1998-03-13 1999-09-27 Pozen, Inc. Prophylaxis and treatment of migraine headaches with thromboxane synthetase inhibitors and/or receptor antagonists
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
JP2005533830A (ja) * 2002-07-09 2005-11-10 ビー.エム.アール.エイ. コーポレイション ベスローテン フェンノートシャップ トロンボキサンa2受容体アンタゴニストおよびcox−2阻害剤の薬剤の組み合わせ
JP2007508242A (ja) * 2003-08-07 2007-04-05 ビー.エム.アール.エイ. コーポレイション ベスローテン フェンノートシャップ トロンボキサンa2受容体アンタゴニストとシクロオキシゲネーゼ−1の阻害剤との組み合わせを伴う組成物および方法
KR101275814B1 (ko) * 2006-06-23 2013-06-18 삼성에스디아이 주식회사 분산제 화합물 및 그의 제조방법
EP2234608A2 (en) 2007-12-11 2010-10-06 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
CN101811974B (zh) * 2010-04-15 2012-12-12 合肥医工医药有限公司 4-(3-(二甲氨基)丙氧基)-3,5-二甲氧基苯甲酸、其制法及医药用途
CN101851209B (zh) * 2010-06-21 2012-09-19 合肥医工医药有限公司 咪唑乙基香草酸醚、其制备方法及其医药用途
CA2874621A1 (en) * 2012-05-22 2013-11-28 Genentech, Inc. N-substituted benzamides and their use in the treatment of pain
AU2013334664A1 (en) 2012-10-26 2015-05-07 Merck Sharp & Dohme Corp. N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels
WO2023240378A1 (zh) * 2022-06-13 2023-12-21 南京医工医药技术有限公司 咪唑烷基香草酸醚衍生物及其用途
CN114736161B (zh) * 2022-06-13 2022-09-13 南京医工医药技术有限公司 咪唑烷基香草酸醚衍生物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3534061A (en) * 1967-12-04 1970-10-13 Parke Davis & Co N-(alpha-(p-methoxyphenyl)-beta-nitrostyryl)-phenoxyalkyl pyrroles
US4085209A (en) * 1975-02-05 1978-04-18 Rohm And Haas Company Preparation and safening effect of 1-substituted imidazole metal salt complexes
US4078071A (en) * 1976-03-08 1978-03-07 Syntex (U.S.A.) Inc. Derivatives of substituted N-alkyl imidazoles
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体

Also Published As

Publication number Publication date
KR830001242A (ko) 1983-04-29
HU183016B (en) 1984-04-28
IT1194900B (it) 1988-09-28
IT7941669A0 (it) 1979-12-11
PH15056A (en) 1982-06-03
NO153135C (no) 1986-01-22
LU81985A1 (fr) 1980-04-22
DK471479A (da) 1980-06-14
FI70888B (fi) 1986-07-18
PL134005B1 (en) 1985-07-31
SU878195A3 (ru) 1981-10-30
NO794069L (no) 1980-06-16
FI793868A7 (fi) 1980-06-14
CH644597A5 (de) 1984-08-15
NL177749B (nl) 1985-06-17
CS216517B2 (en) 1982-11-26
JPS585197B2 (ja) 1983-01-29
KR830001243B1 (ko) 1983-06-27
AR227637A1 (es) 1982-11-30
CA1108137A (en) 1981-09-01
PL220351A1 (es) 1980-12-01
JPS5585572A (en) 1980-06-27
GR73003B (es) 1984-01-24
IE49318B1 (en) 1985-09-18
AU5372579A (en) 1980-06-19
ZA796708B (en) 1981-08-26
DD147943A5 (de) 1981-04-29
ATA783379A (de) 1983-07-15
SE7910204L (sv) 1980-06-14
NL177749C (nl) 1985-11-18
DE2950019A1 (de) 1980-07-10
IL58917A0 (en) 1980-03-31
NO153135B (no) 1985-10-14
AT373879B (de) 1984-02-27
EG14227A (en) 1983-12-31
US4602016A (en) 1986-07-22
FR2444031A1 (fr) 1980-07-11
NL7908899A (nl) 1980-06-17
ES8101556A1 (es) 1980-12-16
SE444937B (sv) 1986-05-20
PT70571A (en) 1980-01-01
FR2444031B1 (es) 1983-06-10
GB2038821B (en) 1982-12-08
GB2038821A (en) 1980-07-30
YU301879A (en) 1983-01-21
US4636500A (en) 1987-01-13
NZ192360A (en) 1982-02-23
AU517892B2 (en) 1981-09-03
BE880584A (fr) 1980-06-12
FI70888C (fi) 1986-10-27
IE792403L (en) 1980-06-13
IL58917A (en) 1984-03-30

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