ES488656A1 - Procedimiento para la preparacion de derivados de acidos aziridin-2-carboxilicos substituidos en n - Google Patents

Procedimiento para la preparacion de derivados de acidos aziridin-2-carboxilicos substituidos en n

Info

Publication number
ES488656A1
ES488656A1 ES488656A ES488656A ES488656A1 ES 488656 A1 ES488656 A1 ES 488656A1 ES 488656 A ES488656 A ES 488656A ES 488656 A ES488656 A ES 488656A ES 488656 A1 ES488656 A1 ES 488656A1
Authority
ES
Spain
Prior art keywords
preparation
substituted
group
alkoxycarbonyl
cyanaziridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES488656A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES488656A1 publication Critical patent/ES488656A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ES488656A 1979-02-21 1980-02-15 Procedimiento para la preparacion de derivados de acidos aziridin-2-carboxilicos substituidos en n Expired ES488656A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792906603 DE2906603A1 (de) 1979-02-21 1979-02-21 N-substituierte aziridin-2-carbonsaeurederivate, verfahren zu deren herstellung sowie diese substanzen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES488656A1 true ES488656A1 (es) 1980-09-16

Family

ID=6063481

Family Applications (1)

Application Number Title Priority Date Filing Date
ES488656A Expired ES488656A1 (es) 1979-02-21 1980-02-15 Procedimiento para la preparacion de derivados de acidos aziridin-2-carboxilicos substituidos en n

Country Status (19)

Country Link
US (2) US4397848A ( )
EP (1) EP0014976B1 ( )
JP (1) JPS55113760A ( )
AR (1) AR223863A1 ( )
AT (1) ATE818T1 ( )
AU (1) AU529982B2 ( )
CA (1) CA1148962A ( )
CS (1) CS208798B2 ( )
DD (1) DD148772A5 ( )
DE (2) DE2906603A1 ( )
ES (1) ES488656A1 ( )
FI (1) FI70702C ( )
HU (1) HU182801B ( )
IE (1) IE49267B1 ( )
IL (1) IL59425A ( )
PL (1) PL129707B1 ( )
PT (1) PT70847A ( )
SU (1) SU1181541A3 ( )
ZA (1) ZA80902B ( )

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925835A (en) * 1986-05-01 1990-05-15 Sloan-Kettering Institute For Cancer Research Aziridinyl putrescine containing compositions and their uses in treating prostate cancer
JPH07301287A (ja) * 1995-03-23 1995-11-14 Sumitomo Heavy Ind Ltd 制御装置に用いられる内接噛合遊星歯車機構
DE69819192T2 (de) 1997-06-27 2004-06-09 Amplimed, Inc., Tucson Neue cyanoaziridine zur behandlung von krebs
US20030129222A1 (en) * 2000-11-21 2003-07-10 Gabriel Lopez-Berestein Liposomal imexon
CA2431947A1 (en) * 2000-11-21 2002-05-30 Gabriel Lopez-Berestein Composition comprising an imexon or derivatives thereof and lipids
ATE374602T1 (de) * 2001-12-21 2007-10-15 Supernus Pharmaceuticals Inc Orale kapselformulierung mit verbesserter physikalischer stabilität
US20040005339A1 (en) * 2002-06-28 2004-01-08 Shojaei Amir H. Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability
MXPA05007485A (es) 2003-01-14 2006-01-30 Arena Pharm Inc Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia.
WO2004076413A2 (en) * 2003-02-24 2004-09-10 Arena Pharmaceuticals, Inc. Phenyl- and pyridylpiperidine-derivatives as modulators of glucose metabolism
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
PL1756084T3 (pl) * 2004-06-04 2009-06-30 Arena Pharm Inc Podstawione pochodne arylowe i heteroarylowe jako modulatory metabolizmu oraz profilaktyka i leczenie zaburzeń z metabolizmem związanych
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
US20100160359A1 (en) * 2005-09-16 2010-06-24 Arena Pharmaceuticals, Inc. Modulators of Metabolism and the Treatment of Disorders Related Thereto
TW200811140A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811147A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ， インコーポレイテッド （Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸およびその塩の調製のためのプロセス
EP3323818A1 (en) 2010-09-22 2018-05-23 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
BR112017027656B1 (pt) 2015-06-22 2023-12-05 Arena Pharmaceuticals, Inc. Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo
MX2019009841A (es) 2017-02-16 2020-01-30 Arena Pharm Inc Compuestos y metodos para el tratamiento de la colangitis biliar primaria.
CA3102136A1 (en) 2018-06-06 2019-12-12 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor
CN113816887A (zh) * 2021-08-31 2021-12-21 华中科技大学 一种氮杂环丙烷类化合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2644820A1 (de) * 1976-10-05 1978-04-06 Boehringer Mannheim Gmbh Cancerostatisch und immunstimulierend wirkende 1-(n-acyl-carbamoyl)-2-cyanaziridine sowie verfahren zur herstellung derselben
DE2731264A1 (de) 1977-07-11 1979-02-01 Boehringer Mannheim Gmbh Neue 1-acyl-2-cyanaziridine, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zubereitungen

Also Published As

Publication number Publication date
US4517183A (en) 1985-05-14
CS208798B2 (en) 1981-09-15
SU1181541A3 (ru) 1985-09-23
JPS55113760A (en) 1980-09-02
PT70847A (de) 1980-03-01
IE49267B1 (en) 1985-09-04
JPH0150700B2 ( ) 1989-10-31
DE3060268D1 (en) 1982-05-19
PL129707B1 (en) 1984-06-30
IL59425A0 (en) 1980-05-30
HU182801B (en) 1984-03-28
EP0014976A1 (de) 1980-09-03
DD148772A5 (de) 1981-06-10
EP0014976B1 (de) 1982-04-07
FI70702C (fi) 1986-10-06
ZA80902B (en) 1981-03-25
IE800327L (en) 1980-08-21
FI70702B (fi) 1986-06-26
AU5564980A (en) 1980-08-28
AU529982B2 (en) 1983-06-30
FI800510A7 (fi) 1980-08-22
AR223863A1 (es) 1981-09-30
IL59425A (en) 1984-05-31
ATE818T1 (de) 1982-04-15
US4397848A (en) 1983-08-09
DE2906603A1 (de) 1980-09-04
PL222088A1 ( ) 1980-12-01
CA1148962A (en) 1983-06-28

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