ES490380A0 - Procedimiento para la preparacion de nuevos derivados indo- licos - Google Patents
Procedimiento para la preparacion de nuevos derivados indo- licosInfo
- Publication number
- ES490380A0 ES490380A0 ES490380A ES490380A ES490380A0 ES 490380 A0 ES490380 A0 ES 490380A0 ES 490380 A ES490380 A ES 490380A ES 490380 A ES490380 A ES 490380A ES 490380 A0 ES490380 A0 ES 490380A0
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- new individual
- individual derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- JHFAEUICJHBVHB-UHFFFAOYSA-N 1h-indol-2-ol Chemical compound C1=CC=C2NC(O)=CC2=C1 JHFAEUICJHBVHB-UHFFFAOYSA-N 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 230000000879 anti-atherosclerotic effect Effects 0.000 abstract 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 abstract 1
- 150000002475 indoles Chemical class 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792909779 DE2909779A1 (de) | 1979-03-13 | 1979-03-13 | Neue indolderivate, deren herstellung und deren verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES490380A0 true ES490380A0 (es) | 1980-12-01 |
| ES8101048A1 ES8101048A1 (es) | 1980-12-01 |
Family
ID=6065240
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES488446A Expired ES488446A1 (es) | 1979-03-13 | 1980-02-11 | Procedimiento para la preparacion de nuevos derivados indo- licos |
| ES490380A Expired ES8101048A1 (es) | 1979-03-13 | 1980-04-09 | Procedimiento para la preparacion de nuevos derivados indo- licos |
| ES490379A Expired ES8101047A1 (es) | 1979-03-13 | 1980-04-09 | Procedimiento para la preparacion de nuevos derivados indo- licos |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES488446A Expired ES488446A1 (es) | 1979-03-13 | 1980-02-11 | Procedimiento para la preparacion de nuevos derivados indo- licos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490379A Expired ES8101047A1 (es) | 1979-03-13 | 1980-04-09 | Procedimiento para la preparacion de nuevos derivados indo- licos |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4343811A (es) |
| EP (1) | EP0015523B1 (es) |
| JP (1) | JPS55124758A (es) |
| AT (1) | ATE1642T1 (es) |
| AU (1) | AU5636880A (es) |
| CA (1) | CA1142519A (es) |
| CS (1) | CS208800B2 (es) |
| DD (1) | DD149804A5 (es) |
| DE (2) | DE2909779A1 (es) |
| ES (3) | ES488446A1 (es) |
| FI (1) | FI800770A7 (es) |
| GR (1) | GR75241B (es) |
| HU (1) | HU180126B (es) |
| IL (1) | IL59598A0 (es) |
| NO (1) | NO800709L (es) |
| NZ (1) | NZ193111A (es) |
| PL (1) | PL222634A1 (es) |
| PT (1) | PT70921B (es) |
| SU (1) | SU1028247A3 (es) |
| YU (1) | YU68180A (es) |
| ZA (1) | ZA801441B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA814057B (en) * | 1980-06-18 | 1982-07-28 | May & Baker Ltd | Indole and indoline derivatives |
| DE3232968A1 (de) * | 1981-09-10 | 1983-06-09 | Degussa Ag, 6000 Frankfurt | Neue 2-(hydroxy-phenyl)-indole und verfahren zu deren herstellung |
| US4543360A (en) * | 1981-09-10 | 1985-09-24 | Degussa Aktiengesellschaft | 2-(Hydroxy-phenyl)-indoles and process for their production |
| US4478842A (en) * | 1981-11-19 | 1984-10-23 | Ciba-Geigy Corporation | N-Substituted-2-pyridylindoles |
| US4460777A (en) * | 1981-11-19 | 1984-07-17 | Ciba-Geigy Corporation | N-Substituted-2-pyridylindoles |
| GB2111050B (en) * | 1981-11-19 | 1985-09-11 | Ciba Geigy Ag | N-substituted-2-pyridylindoles |
| US4647576A (en) * | 1984-09-24 | 1987-03-03 | Warner-Lambert Company | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis |
| US4759923A (en) * | 1987-06-25 | 1988-07-26 | Hercules Incorporated | Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives |
| HUP9903330A2 (hu) | 1996-11-19 | 2000-03-28 | Amgen Inc. | Gyulladásgátló hatású, aril- és heteroaril csoporttal szubsztituált kondenzált pirrolszármazékok, valamint ezeket tartalmazó gyógyászati készítmények |
| US6103733A (en) * | 1998-09-09 | 2000-08-15 | Bachmann; Kenneth A. | Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes |
| US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| US7772271B2 (en) | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| EP1781289A1 (en) | 2004-07-22 | 2007-05-09 | PTC Therapeutics, Inc. | Thienopyridines for treating hepatitis c |
| DE102006053064A1 (de) * | 2006-11-08 | 2008-05-21 | Universität Potsdam | Verfahren zur Herstellung aromatischer Diazoniumsalze |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2237361A1 (de) * | 1972-07-29 | 1974-02-14 | Boehringer Mannheim Gmbh | (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben |
| FI59246C (fi) * | 1974-06-24 | 1981-07-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin |
-
1979
- 1979-03-13 DE DE19792909779 patent/DE2909779A1/de not_active Withdrawn
-
1980
- 1980-02-11 ES ES488446A patent/ES488446A1/es not_active Expired
- 1980-02-12 SU SU802879303A patent/SU1028247A3/ru active
- 1980-02-19 GR GR61231A patent/GR75241B/el unknown
- 1980-02-29 US US06/126,006 patent/US4343811A/en not_active Expired - Lifetime
- 1980-03-03 DE DE8080101037T patent/DE3060932D1/de not_active Expired
- 1980-03-03 AT AT80101037T patent/ATE1642T1/de not_active IP Right Cessation
- 1980-03-03 EP EP80101037A patent/EP0015523B1/de not_active Expired
- 1980-03-10 PT PT70921A patent/PT70921B/pt unknown
- 1980-03-10 DD DD80219568A patent/DD149804A5/de unknown
- 1980-03-11 CS CS801663A patent/CS208800B2/cs unknown
- 1980-03-11 JP JP3083480A patent/JPS55124758A/ja active Pending
- 1980-03-12 IL IL59598A patent/IL59598A0/xx unknown
- 1980-03-12 HU HU8080591A patent/HU180126B/hu unknown
- 1980-03-12 NZ NZ193111A patent/NZ193111A/xx unknown
- 1980-03-12 ZA ZA00801441A patent/ZA801441B/xx unknown
- 1980-03-12 AU AU56368/80A patent/AU5636880A/en not_active Abandoned
- 1980-03-12 PL PL22263480A patent/PL222634A1/xx unknown
- 1980-03-12 NO NO800709A patent/NO800709L/no unknown
- 1980-03-12 FI FI800770A patent/FI800770A7/fi not_active Application Discontinuation
- 1980-03-12 CA CA000347485A patent/CA1142519A/en not_active Expired
- 1980-03-12 YU YU00681/80A patent/YU68180A/xx unknown
- 1980-04-09 ES ES490380A patent/ES8101048A1/es not_active Expired
- 1980-04-09 ES ES490379A patent/ES8101047A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GR75241B (es) | 1984-07-13 |
| ES490379A0 (es) | 1980-12-01 |
| US4343811A (en) | 1982-08-10 |
| AU5636880A (en) | 1980-09-18 |
| SU1028247A3 (ru) | 1983-07-07 |
| CA1142519A (en) | 1983-03-08 |
| EP0015523A1 (de) | 1980-09-17 |
| PT70921B (de) | 1981-06-24 |
| DE3060932D1 (en) | 1982-11-18 |
| ES8101047A1 (es) | 1980-12-01 |
| NZ193111A (en) | 1983-04-12 |
| EP0015523B1 (de) | 1982-10-13 |
| HU180126B (en) | 1983-02-28 |
| CS208800B2 (en) | 1981-09-15 |
| DD149804A5 (de) | 1981-07-29 |
| IL59598A0 (en) | 1980-06-30 |
| PL222634A1 (es) | 1980-12-01 |
| JPS55124758A (en) | 1980-09-26 |
| DE2909779A1 (de) | 1980-09-18 |
| YU68180A (en) | 1983-04-30 |
| ES8101048A1 (es) | 1980-12-01 |
| ES488446A1 (es) | 1980-10-01 |
| ZA801441B (en) | 1981-11-25 |
| FI800770A7 (fi) | 1981-01-01 |
| PT70921A (de) | 1980-04-01 |
| NO800709L (no) | 1980-09-15 |
| ATE1642T1 (de) | 1982-10-15 |
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