ES514852A0 - "procedimiento para la preparacion de nuevos derivados de ciclofosfamida". - Google Patents

"procedimiento para la preparacion de nuevos derivados de ciclofosfamida".

Info

Publication number
ES514852A0
ES514852A0 ES514852A ES514852A ES514852A0 ES 514852 A0 ES514852 A0 ES 514852A0 ES 514852 A ES514852 A ES 514852A ES 514852 A ES514852 A ES 514852A ES 514852 A0 ES514852 A0 ES 514852A0
Authority
ES
Spain
Prior art keywords
procedure
preparation
new
cyclophosphamide derivatives
cyclophosphamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES514852A
Other languages
English (en)
Other versions
ES8400752A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV
Original Assignee
Behringwerke AG
Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG, Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV filed Critical Behringwerke AG
Publication of ES514852A0 publication Critical patent/ES514852A0/es
Publication of ES8400752A1 publication Critical patent/ES8400752A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES514852A 1981-08-14 1982-08-09 "procedimiento para la preparacion de nuevos derivados de ciclofosfamida". Expired ES8400752A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813132221 DE3132221A1 (de) 1981-08-14 1981-08-14 Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
ES514852A0 true ES514852A0 (es) 1983-11-01
ES8400752A1 ES8400752A1 (es) 1983-11-01

Family

ID=6139355

Family Applications (1)

Application Number Title Priority Date Filing Date
ES514852A Expired ES8400752A1 (es) 1981-08-14 1982-08-09 "procedimiento para la preparacion de nuevos derivados de ciclofosfamida".

Country Status (8)

Country Link
EP (1) EP0072531A1 (es)
JP (1) JPS5841892A (es)
AU (1) AU8717082A (es)
DE (1) DE3132221A1 (es)
DK (1) DK364782A (es)
ES (1) ES8400752A1 (es)
PT (1) PT75416B (es)
ZA (1) ZA825876B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3225227A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Derivate des n.n-bis-(2-chlor-aethyl)-phosphorsaeureamids
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
FR2684102B1 (fr) * 1991-11-21 1994-03-11 Etat Francais Delegue Armement Procede de preparation de polyazidoalcools ainsi que de polyaminoalcools et polyazidothiols derives de ceux-ci.
EP1634886A3 (en) * 1999-03-05 2006-03-29 Metabasis Therapeutics, Inc. Novel phosphorus-containing prodrug
SK12442001A3 (sk) * 1999-03-05 2002-06-04 Metabasis Therapeutics, Inc. Cyklické fosforamidáty, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú
US7205404B1 (en) 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US6506739B1 (en) 2001-05-01 2003-01-14 Telik, Inc. Bis-(N,N'-bis-(2-haloethyl)amino)phosphoramidates as antitumor agents
FR2968662B1 (fr) * 2010-12-10 2013-11-22 Roussy Inst Gustave Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation
EP3623364A1 (en) 2014-02-13 2020-03-18 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
CN106687118A (zh) 2014-07-02 2017-05-17 配体药物公司 前药化合物及其用途
WO2019139919A1 (en) 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE554888A (es) * 1956-12-20
JPS5230519B2 (es) * 1972-04-05 1977-08-09
PL100390B1 (pl) * 1975-10-06 1978-09-30 Sposob wytwarzania 2-tlenku-2-/bis/2-chloroetylo/-amino/-1-/okso-3-aza-2-fosfacykloheksanu/cyklofosfamidu/o czynnosci optycznej

Also Published As

Publication number Publication date
DE3132221A1 (de) 1983-05-19
PT75416B (de) 1985-05-31
EP0072531A1 (de) 1983-02-23
AU8717082A (en) 1983-02-17
ES8400752A1 (es) 1983-11-01
PT75416A (de) 1982-09-01
JPS5841892A (ja) 1983-03-11
DK364782A (da) 1983-02-15
ZA825876B (en) 1983-06-29

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