ES521635A0 - Un procedimiento para la preparacion de nuevos derivados de fosfolipidos. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de fosfolipidos.

Info

Publication number
ES521635A0
ES521635A0 ES521635A ES521635A ES521635A0 ES 521635 A0 ES521635 A0 ES 521635A0 ES 521635 A ES521635 A ES 521635A ES 521635 A ES521635 A ES 521635A ES 521635 A0 ES521635 A0 ES 521635A0
Authority
ES
Spain
Prior art keywords
phosfolipids
procedure
preparation
new derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES521635A
Other languages
English (en)
Other versions
ES8406080A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES521635A0 publication Critical patent/ES521635A0/es
Publication of ES8406080A1 publication Critical patent/ES8406080A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/13—Saturated ethers containing hydroxy or O-metal groups
    • C07C43/135—Saturated ethers containing hydroxy or O-metal groups having more than one ether bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4075—Esters with hydroxyalkyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES521635A 1982-04-19 1983-04-19 Un procedimiento para la preparacion de nuevos derivados de fosfolipidos. Expired ES8406080A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8211284 1982-04-19

Publications (2)

Publication Number Publication Date
ES521635A0 true ES521635A0 (es) 1984-07-01
ES8406080A1 ES8406080A1 (es) 1984-07-01

Family

ID=10529776

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521635A Expired ES8406080A1 (es) 1982-04-19 1983-04-19 Un procedimiento para la preparacion de nuevos derivados de fosfolipidos.

Country Status (7)

Country Link
US (1) US4562179A (es)
EP (1) EP0092190B1 (es)
JP (1) JPS58189191A (es)
KR (1) KR840004441A (es)
DE (1) DE3366393D1 (es)
DK (1) DK164383A (es)
ES (1) ES8406080A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3239817A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Neue glycerinderivate zur synthese von phospholipiden
DE3323871A1 (de) * 1983-07-02 1985-01-03 A. Nattermann & Cie GmbH, 5000 Köln Neue 1-o-alkyl-3-amino-propan-1,2-diol-2-o-phospholipide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
CA1264162A (en) * 1984-03-15 1990-01-02 Manfred Breuninger Glycerol ether phosphatides
US4659859A (en) * 1984-07-02 1987-04-21 Eli Lilly And Company 2-alkoxy-1-alkoxy phosphoryl dichlorides
US4647685A (en) * 1985-04-25 1987-03-03 Eli Lilly And Company 2-alkoxy-1-((2-trialkylaminoethoxy)phosphinyloxy)-alkenes and alkynes, hydroxy inner salts
US5290769A (en) * 1989-09-27 1994-03-01 Asta Pharma Aktiengesellschaft Use of hexadecylphosphocholine for the treatment of psoriasis
GR1000688B (el) * 1989-12-22 1992-10-08 Sod Conseils Rech Applic Μεθοδος παρασκευης παραγωγων γλυκερινης.
US5506217A (en) * 1991-04-25 1996-04-09 The University Of British Columbia Phosphonates as anti-cancer agents
US5369097A (en) * 1991-04-25 1994-11-29 The University Of British Columbia Phosphonates as anti-cancer agents
EP0581793A1 (en) * 1991-04-25 1994-02-09 University Of British Columbia Phosphonates and phosphinates as anti-cancer, -inflammatory, -allergy and -myocarditis agents
DE4234130A1 (de) * 1992-10-09 1994-04-14 Max Planck Gesellschaft Phospholipase A¶2¶ inhibierende Phosphatidylcholinverbindungen
CN1132586C (zh) 1993-09-09 2003-12-31 罗拉斯医疗公司 来自胆汁的免疫调节组合物、其制备方法及其用途
US6551623B1 (en) 1993-09-09 2003-04-22 Lorus Therapeutics Inc. Immunomodulating compositions from bile
US5651981A (en) * 1994-03-29 1997-07-29 Northwestern University Cationic phospholipids for transfection
BR9607967A (pt) 1995-03-16 1998-01-13 Imutec Pharma Inc Uso de composições imunomodulares extraídas da bile para o tratamento das desordens do sistema imunológico fabricação do medicamento e emprego do mesmo
US20040101569A1 (en) * 1996-05-16 2004-05-27 Lorus Therapeutics Inc. Immunomodulating compositions from bile
AU2001278336B2 (en) * 2000-07-31 2007-01-18 Ottawa Heart Institute Research Corporation Charged phospholipid compositions and methods for their use
DK174896B1 (da) 2000-12-08 2004-02-02 Sfk Danfotech As Apparatur for opskæring af bugen på slagtede dyr, fremgangsmåde dertil samt anvendelse af apparatur og fremgangsmåde
WO2004062595A2 (en) * 2003-01-09 2004-07-29 Zeneus Pharma Limited Antineoplastic ether lipid compounds with modifications at the sn-1 carbon
EP1587518A4 (en) * 2003-01-09 2008-08-20 Zeneus Pharma Ltd ANTINEOPLASTIC LIPIDIC ETHER COMPOUNDS HAVING MODIFICATIONS AT THE CARBON GROUP SN-3
WO2004062586A2 (en) * 2003-01-09 2004-07-29 Zeneus Pharma Limited Antineoplastic ether lipid compounds
US20050187192A1 (en) * 2004-02-20 2005-08-25 Kucera Pharmaceutical Company Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses
WO2005087788A2 (en) * 2004-03-04 2005-09-22 The Regents Of The University Of California Methods for preparation of nucleoside phosphonate esters
CN1984663A (zh) 2004-03-29 2007-06-20 南佛罗里达大学 用曲西瑞宾和相关化合物有效治疗肿瘤和癌症
WO2006110655A2 (en) 2005-04-08 2006-10-19 Chimerix, Inc. Compounds, compositions and methods for the treatment of poxvirus infections
CN105055432A (zh) 2008-01-25 2015-11-18 奇默里克斯公司 治疗病毒感染的方法
US8614200B2 (en) 2009-07-21 2013-12-24 Chimerix, Inc. Compounds, compositions and methods for treating ocular conditions
CA2789443C (en) 2010-02-12 2016-09-13 Chimerix, Inc. Nucleoside phosphonate salts
EP2563367A4 (en) 2010-04-26 2013-12-04 Chimerix Inc Methods of treating retroviral infections and related dosage regimes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2619686C2 (de) * 1976-05-04 1986-08-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verwendung eines Lysolecithins zur Tumorbehandlung
DE2619715A1 (de) * 1976-05-04 1977-11-24 Max Planck Gesellschaft Tumor-antigen und verfahren zu dessen herstellung
DE2820893C2 (de) * 1978-05-12 1986-02-20 A. Nattermann & Cie GmbH, 5000 Köln Strukturanaloga von natürlichen Phospholipiden und Verfahren zur Herstellung dieser Verbindungen
US4408052A (en) * 1980-02-27 1983-10-04 Takeda Chemical Industries, Ltd. Phospholipid carbamates
JPS5772914A (en) * 1980-10-22 1982-05-07 Takeda Chem Ind Ltd Antitumor agent
US4493832A (en) * 1981-07-03 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same
DK328182A (da) * 1981-07-31 1983-02-01 Fujisawa Pharmaceutical Co Fremgangsmaade til fremstilling af phospholipidderivater

Also Published As

Publication number Publication date
DK164383A (da) 1983-10-20
EP0092190A3 (en) 1984-02-01
EP0092190B1 (en) 1986-09-24
DE3366393D1 (en) 1986-10-30
KR840004441A (ko) 1984-10-15
JPS58189191A (ja) 1983-11-04
US4562179A (en) 1985-12-31
DK164383D0 (da) 1983-04-14
EP0092190A2 (en) 1983-10-26
ES8406080A1 (es) 1984-07-01

Similar Documents

Publication Publication Date Title
ES521121A0 (es) Un procedimiento para la preparacion de derivados de benzotia-zolsulfonamida.
ES528630A0 (es) Un procedimiento para la obtencion de derivados de hexahidro-3-oxo-piridinas.
ES518225A0 (es) Un procedimiento para la preparacion de nuevos derivados de oxabicicloalcano.
ES520132A0 (es) Un procedimiento para la preparacion de derivados de 1-normon-2-ilo.
ES524446A0 (es) Un procedimiento para la preparacion de nuevos derivados.
ES520730A0 (es) Un procedimiento para la prepracion de nuevas benzolactamas.
ES522678A0 (es) Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina.
ES524447A0 (es) Un procedimiento para la preparacion de nuevos derivados arilfenolicos.
ES512880A0 (es) Un procedimiento para la preparacion de derivados de 4-anilino-pirimidina.
ES505922A0 (es) Un procedimiento para la preparacion de nuevos derivados de cefalospirina.
ES516825A0 (es) Un procedimiento para la preparacion de nuevos derivados de 3-amino-pregn-5-eno.
ES524610A0 (es) Un procedimiento para la preparacion de nuevos derivados de fosfolipidos.
ES522120A0 (es) Un procedimiento para la preparacion de 4-aril-4-piperidincarbinoles.
ES524317A0 (es) Un procedimiento para la preparacion de nuevos derivados de tienopirimidina.
ES510067A0 (es) Un procedimiento para la preparacion de nuevos derivados de benzoilurea.
ES511224A0 (es) Un procedimiento para la preparacion de nuevos derivados de 2-piperazino pirimioina.
ES521192A0 (es) Un procedimiento para la preparacion de derivados de b-lactama.
ES533389A0 (es) Un procedimiento para la preparacion de nuevos derivados de tiosulfonamida.
ES504793A0 (es) Un procedimiento para la preparacion de nuevos derivados de caprilolactama.
ES534642A0 (es) Un procedimiento para la preparacion de nuevos derivados de carbaciclina.
ES522389A0 (es) Un procedimiento para la preparacion de nuevos derivados de penem-2-tiosustituidos.
ES534269A0 (es) Un procedimiento para la preparacion de nuevos derivados de difeniletanona.
ES507482A0 (es) Un procedimiento para la preparacion de nuevos derivados de acilaminoquimazolina.
ES526528A0 (es) Un procedimiento para la preparacion de derivados de difenilalquilenicos.
ES527780A0 (es) Un procedimiento para la preparacion de nuevas espiro-3-azolindionas.