ES522678A0 - Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina.

Info

Publication number
ES522678A0
ES522678A0 ES522678A ES522678A ES522678A0 ES 522678 A0 ES522678 A0 ES 522678A0 ES 522678 A ES522678 A ES 522678A ES 522678 A ES522678 A ES 522678A ES 522678 A0 ES522678 A0 ES 522678A0
Authority
ES
Spain
Prior art keywords
oxo
procedure
preparation
new
imidazoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES522678A
Other languages
English (en)
Other versions
ES8503667A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of ES8503667A1 publication Critical patent/ES8503667A1/es
Publication of ES522678A0 publication Critical patent/ES522678A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES522678A 1982-05-24 1983-05-24 Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina. Granted ES522678A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57088637A JPS6058233B2 (ja) 1982-05-24 1982-05-24 ２−オキソイミダゾリジン誘導体及びその製法

Publications (2)

Publication Number Publication Date
ES8503667A1 ES8503667A1 (es) 1985-03-16
ES522678A0 true ES522678A0 (es) 1985-03-16

Family

ID=13948325

Family Applications (2)

Application Number Title Priority Date Filing Date
ES522678A Granted ES522678A0 (es) 1982-05-24 1983-05-24 Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina.
ES535980A Expired ES8603427A1 (es) 1982-05-24 1984-09-17 Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES535980A Expired ES8603427A1 (es) 1982-05-24 1984-09-17 Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina

Country Status (8)

Country Link
US (1) US4508727A (es)
EP (1) EP0095163B1 (es)
JP (1) JPS6058233B2 (es)
DE (2) DE19975013I1 (es)
ES (2) ES522678A0 (es)
HK (1) HK32689A (es)
MY (1) MY100095A (es)
SG (1) SG5989G (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61293538A (ja) * 1985-06-24 1986-12-24 Shinto Paint Co Ltd 固体または半固体溶質の溶媒による溶解方法
KR930004646B1 (ko) * 1986-12-09 1993-06-02 다나베 세이야꾸 가부시끼가이샤 심기능 부전의 예방 및 치료제
US4804672A (en) * 1986-12-12 1989-02-14 Tanabe Seiyaku Co., Ltd. 2-oxo-imidazolidine derivatives as agents for treatment of kidney diseases
FR2620700B1 (fr) * 1987-09-17 1990-06-01 Adir Procede de synthese d'alpha amino acides n alkyles et leurs esters. application a la synthese de carboxyalkyl dipeptides
JPH0645603B2 (ja) * 1988-12-16 1994-06-15 田辺製薬株式会社 光学活性２‐オキソイミダゾリジン誘導体の製法
JPH07121916B2 (ja) * 1993-12-10 1995-12-25 田辺製薬株式会社 光学活性３−アシル−２−オキソイミダゾリジン−４−カルボン酸誘導体及びその製法
EP1545519B1 (en) 2002-08-19 2011-03-23 Pfizer Inc. Combination therapy for hyperproliferative diseases
CL2004000366A1 (es) * 2003-02-26 2005-01-07 Pharmacia Corp Sa Organizada B USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
JP4780437B2 (ja) * 2004-12-08 2011-09-28 大原薬品工業株式会社 ２−オキソイミダゾリジン誘導体の製造方法
JP4799085B2 (ja) * 2005-09-02 2011-10-19 株式会社カネカ 光学活性ｎ置換アミノアシル環状尿素誘導体の製造法
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
JP5206926B2 (ja) * 2007-07-30 2013-06-12 株式会社Ｄｎｐファインケミカル宇都宮 塩酸イミダプリルの製造方法
US9446032B2 (en) 2011-08-26 2016-09-20 Wockhardt Limited Methods for treating cardiovascular disorders
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
CN104119424B (zh) * 2014-07-01 2018-12-18 上海天慈生物谷生物工程有限公司 (4s)-3-[(2s)-2[(1s)-1-乙氧羰基-3-苯丙基]氨基丙酰基]-1-甲基-2-氧代咪唑啉-4-羧酸的制备方法
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN105713068B (zh) * 2014-12-04 2021-04-20 湖南九典制药股份有限公司 一种制备咪达普利关键中间体及其衍生物的方法
US11248001B2 (en) 2019-01-18 2022-02-15 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
EP0048159A3 (en) * 1980-09-17 1982-05-12 University Of Miami Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents
US4296110A (en) * 1980-10-28 1981-10-20 E. I. Du Pont De Nemours And Company Antihypertensive I-substituted cyclic lactam-2-carboxylic acids
JPS5788165A (en) * 1980-11-21 1982-06-01 Tanabe Seiyaku Co Ltd 2-oxoimidazolidine-4-carboxylic acid derivative and its preparation
JPS5835114A (ja) * 1981-08-21 1983-03-01 ザ・ユニバ−シイテイ・オブ・マイアミ 抗高血圧剤

Also Published As

Publication number Publication date
MY100095A (en) 1989-10-10
EP0095163B1 (en) 1987-08-19
HK32689A (en) 1989-04-28
SG5989G (en) 1989-06-09
US4508727A (en) 1985-04-02
DE19975013I1 (de) 2003-09-04
DE3373100D1 (en) 1987-09-24
EP0095163A3 (en) 1984-09-12
JPS58203971A (ja) 1983-11-28
ES535980A0 (es) 1985-12-16
ES8503667A1 (es) 1985-03-16
ES8603427A1 (es) 1985-12-16
JPS6058233B2 (ja) 1985-12-19
EP0095163A2 (en) 1983-11-30

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