ES525327A0 - Aminoalquilesteroides. - Google Patents

Aminoalquilesteroides.

Info

Publication number: ES525327A0
Authority: ES; Spain
Prior art keywords: amino alkyl; alkyl steroids; steroids; amino; alkyl
Prior art date: 1982-09-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES525327A

Other languages

English (en)

Other versions

ES8603508A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

GD Searle LLC

Original Assignee

GD Searle LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-09-03

Filing date

1983-09-02

Publication date

1985-12-16

1983-09-02 Application filed by GD Searle LLC filed Critical GD Searle LLC

1985-12-16 Publication of ES8603508A1 publication Critical patent/ES8603508A1/es

1985-12-16 Publication of ES525327A0 publication Critical patent/ES525327A0/es

Status Granted legal-status Critical Current

Links

-1 AMINO Chemical class 0.000 title 1
150000003431 steroids Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Anesthesiology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES525327A 1982-09-03 1983-09-02 Aminoalquilesteroides. Granted ES525327A0 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/414,717 US4495102A (en)	1982-09-03	1982-09-03	Aminoalkyl steroids
AU18618/83A AU560812B2 (en)	1982-09-03	1983-09-01	Aminoalkyl steroids

Publications (2)

Publication Number	Publication Date
ES8603508A1 ES8603508A1 (es)	1985-12-16
ES525327A0 true ES525327A0 (es)	1985-12-16

Family

ID=36764519

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES525327A Granted ES525327A0 (es)	1982-09-03	1983-09-02	Aminoalquilesteroides.

Country Status (7)

Country	Link
US (1)	US4495102A (es)
EP (1)	EP0104489B1 (es)
JP (2)	JPS5965100A (es)
AU (1)	AU560812B2 (es)
DE (1)	DE3368063D1 (es)
ES (1)	ES525327A0 (es)
ZA (1)	ZA836263B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4910191A (en) *	1988-06-28	1990-03-20	Merrell Dow Pharmaceuticals Inc.	19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
FR2656309B1 (fr) *	1989-12-22	1992-05-07	Roussel Uclaf	Nouveaux produits sterouides comportant en position 10, un radical ethyle substitue, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
US6372712B1 (en)	1998-05-22	2002-04-16	The Board Of Trustees Of The Leland Stanford Jr. University	Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand
EP2671508B1 (en)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Pharma-informatics system
US9062126B2 (en)	2005-09-16	2015-06-23	Raptor Pharmaceuticals Inc.	Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko)	2009-05-06	2018-10-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US9388210B2 (en)	2011-02-25	2016-07-12	Washington University	Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
EP4717314A2 (en)	2011-10-14	2026-04-01	Sage Therapeutics, LLC	3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof
DK2935307T3 (en) *	2012-12-18	2018-07-30	Univ Washington	NEUROACTIVE 19-ALKOXY-17-SUBSTITUTED STEROIDS USED IN METHODS OF TREATMENT
US9512170B2 (en)	2013-03-01	2016-12-06	Washington University	Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en)	2013-03-11	2016-06-14	Washington University	Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en)	2013-03-14	2017-02-07	Washington University	Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
CN117304245A (zh)	2013-04-17	2023-12-29	萨奇治疗股份有限公司	刺激神经活性的19-去甲类固醇及其使用方法
US9725481B2 (en)	2013-04-17	2017-08-08	Sage Therapeutics, Inc.	19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
WO2014169836A1 (en)	2013-04-17	2014-10-23	Sage Therapeutics, Inc.	19-nor neuroactive steroids and methods of use thereof
SMT202100509T1 (it)	2013-04-17	2021-11-12	Sage Therapeutics Inc	Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia
CA2918735C (en)	2013-07-19	2023-08-01	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
CN105579043B (zh)	2013-08-23	2021-09-14	萨奇治疗股份有限公司	神经活性类固醇、组合物和其用途
US10246482B2 (en)	2014-06-18	2019-04-02	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
US20170233433A1 (en)	2014-10-16	2017-08-17	Sage Therapeutics, Inc.	Compositions and methods for treating cns disorders
MY190408A (en)	2014-10-16	2022-04-21	Sage Therapeutics Inc	Compositions and methods for treating cns disorders
WO2016082789A1 (en)	2014-11-27	2016-06-02	Sage Therapeutics, Inc.	Compositions and methods for treating cns disorders
LT3250210T (lt)	2015-01-26	2021-04-12	Sage Therapeutics, Inc.	Kompozicijos ir būdai, skirti gydyti cns sutrikimus
DK3258939T3 (da)	2015-02-20	2022-12-12	Sage Therapeutics Inc	Neuroaktive steroider, sammensætninger og anvendelser heraf
WO2018013613A1 (en)	2016-07-11	2018-01-18	Sage Therapeutics, Inc.	C17, c20, and c21 substituted neuroactive steroids and their methods of use
CA3030420C (en)	2016-07-11	2025-11-18	Sage Therapeutics, Inc.	C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE
JP7670626B2 (ja)	2019-05-31	2025-04-30	セージセラピューティクス，インコーポレイテッド	神経刺激性ステロイド及びその組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3278565A (en) *	1962-12-20	1966-10-11	Syntex Corp	19-aminoandrostenes and -10alpha-androstenes
US3275621A (en) *	1963-12-18	1966-09-27	Syntex Corp	19-amino-delta4-pregnenes and-10alpha-pregnenes and process for their preparation
NL7008956A (es) *	1969-06-25	1970-12-29
JPS5314555A (en) *	1976-07-26	1978-02-09	Hitachi Ltd	Depositing method of impurity to silicon wafersa
US4191759A (en) *	1978-04-13	1980-03-04	Merck & Co., Inc.	N-substituted-17β-carbamoylandrost-4-en-3-one 5α reductase inhibitors
DE2856578C2 (de) *	1978-12-22	1980-11-06	Schering Ag, 1000 Berlin Und 4619 Bergkamen	16-Dimethylaminomethylen:3-methoxy-1.3.5(10)-östratrien-17-on, Verfahren zu dessen Herstellung und seine Weiterverarbeitung
US4289762A (en) *	1980-06-27	1981-09-15	Merrell Dow Pharmaceuticals Inc.	10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors

1982
- 1982-09-03 US US06/414,717 patent/US4495102A/en not_active Expired - Fee Related
1983
- 1983-08-24 ZA ZA836263A patent/ZA836263B/xx unknown
- 1983-09-01 DE DE8383108617T patent/DE3368063D1/de not_active Expired
- 1983-09-01 AU AU18618/83A patent/AU560812B2/en not_active Ceased
- 1983-09-01 EP EP83108617A patent/EP0104489B1/en not_active Expired
- 1983-09-02 ES ES525327A patent/ES525327A0/es active Granted
- 1983-09-02 JP JP58161773A patent/JPS5965100A/ja active Granted
1992
- 1992-01-23 JP JP4009691A patent/JPH0559096A/ja active Pending

Also Published As

Publication number	Publication date
ZA836263B (en)	1984-10-31
ES8603508A1 (es)	1985-12-16
US4495102A (en)	1985-01-22
JPS5965100A (ja)	1984-04-13
AU1861883A (en)	1984-03-29
AU560812B2 (en)	1987-04-16
JPH0559096A (ja)	1993-03-09
JPH056558B2 (es)	1993-01-26
EP0104489B1 (en)	1986-12-03
DE3368063D1 (de)	1987-01-15
EP0104489A1 (en)	1984-04-04

Publication	Publication Date	Title
IT1205626B (it)	1989-03-23	Glicin-8-calcitonina
BE895653A (fr)	1983-05-16	Katalytische verbrander
FI833329L (fi)	1984-03-21	Genomfloedesmaengdreglerare
DK159092C (da)	1991-02-04	Pattegummi til pattekop
IT1169734B (it)	1987-06-03	Pirazolopiridin derivato
MA19678A1 (fr)	1983-10-01	Agents anti-helmintiques.
FI842788L (fi)	1984-07-11	Taktisk kompass foer segeljolle.
FI833959L (fi)	1984-04-30	Orala kompositioner
BE894865A (fr)	1983-04-29	Biertransportwagen
AT381170B (de)	1986-09-10	Hypsometer
AT373020B (de)	1983-12-12	Ruestungstraeger
AT382452B (de)	1987-02-25	Drehrohrofen
BE895597A (fr)	1983-05-02	Verwarmingsstelsel
SE8206611D0 (sv)	1982-11-19	Tandsticka
FI833769L (fi)	1984-05-11	Spaennband foer haorpapiljott
SE8205047L (sv)	1984-03-07	Hervavskerare for statorlindningar
BR6201085U (pt)	1984-03-20	Fecho
BR8203688A (pt)	1984-01-31	Fecho
AR226015A1 (es)	1982-05-14	Catre-reposera
AR225385A1 (es)	1982-03-15	Jeringa-ampolla
BR8202095A (pt)	1983-11-22	Salitradeira
BR8202644A (pt)	1983-12-13	Micro - irrigador
ATA13982A (de)	1985-03-15	Schistock
BR6200467U (pt)	1983-11-16	Pantalha
BR8204630A (pt)	1984-03-13	Emissor-conversor eletrootico