ES531284A0 - Procedimiento para preparar esteres de acidos imino-&-carboxilicos biciclicos opticamente puros - Google Patents

Procedimiento para preparar esteres de acidos imino-&-carboxilicos biciclicos opticamente puros

Info

Publication number
ES531284A0
ES531284A0 ES531284A ES531284A ES531284A0 ES 531284 A0 ES531284 A0 ES 531284A0 ES 531284 A ES531284 A ES 531284A ES 531284 A ES531284 A ES 531284A ES 531284 A0 ES531284 A0 ES 531284A0
Authority
ES
Spain
Prior art keywords
carboxylics
procedure
optically pure
imino acids
preparing esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES531284A
Other languages
English (en)
Other versions
ES8501759A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19833303112 external-priority patent/DE3303112A1/de
Priority claimed from DE19833303139 external-priority patent/DE3303139A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES531284A0 publication Critical patent/ES531284A0/es
Publication of ES8501759A1 publication Critical patent/ES8501759A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES531284A 1983-01-31 1984-04-04 Procedimiento para preparar esteres de acidos imino-&-carboxilicos biciclicos opticamente puros Expired ES8501759A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833303112 DE3303112A1 (de) 1983-01-31 1983-01-31 Verfahren zur racemattrennung optisch aktiver bicyclischer imino-(alpha)-carbonsaeuren
DE19833303139 DE3303139A1 (de) 1983-01-31 1983-01-31 Verfahren zur herstellung von carboxyalkyldipeptiden

Publications (2)

Publication Number Publication Date
ES531284A0 true ES531284A0 (es) 1984-12-01
ES8501759A1 ES8501759A1 (es) 1984-12-01

Family

ID=25807929

Family Applications (2)

Application Number Title Priority Date Filing Date
ES529272A Expired ES8500228A1 (es) 1983-01-31 1984-01-30 Procedimiento para desdoblar mezclas racemicas de esteres de acidos imino- -carboxilicos biciclicos
ES531284A Expired ES8501759A1 (es) 1983-01-31 1984-04-04 Procedimiento para preparar esteres de acidos imino-&-carboxilicos biciclicos opticamente puros

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES529272A Expired ES8500228A1 (es) 1983-01-31 1984-01-30 Procedimiento para desdoblar mezclas racemicas de esteres de acidos imino- -carboxilicos biciclicos

Country Status (17)

Country Link
EP (1) EP0115345B1 (es)
JP (1) JPH0788358B2 (es)
KR (1) KR910001438B1 (es)
AU (1) AU566589B2 (es)
CA (2) CA1283249C (es)
DE (1) DE3468415D1 (es)
DK (1) DK174386B1 (es)
ES (2) ES8500228A1 (es)
FI (1) FI88153C (es)
GR (1) GR82650B (es)
HU (1) HU191120B (es)
IE (1) IE56654B1 (es)
IL (1) IL70830A (es)
MA (1) MA20020A1 (es)
NO (1) NO166641C (es)
NZ (1) NZ206980A (es)
PT (1) PT78036B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500713A (en) * 1982-09-23 1985-02-19 Usv Pharmaceutical Corporation Therapeutic dipeptides
DE3345355A1 (de) * 1983-12-15 1985-06-27 Hoechst Ag, 6230 Frankfurt Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester
JPS61502818A (ja) * 1984-07-30 1986-12-04 シェリング・コ−ポレ−ション シス、エンド−オクタヒドロシクロペンタ〔b〕ピロ−ル−2−カルボキシレ−トの新規製造方法
HU192914B (en) * 1985-02-11 1987-07-28 Richter Gedeon Vegyeszet Process for producing new 3-/substituted amino/-5-phenyl-2/3h/-furanone derivatives and pharmaceutically acceptable salts
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
US6407262B1 (en) 2001-11-21 2002-06-18 Brantford Chemicals Inc. Process for the preparation of Ramipril
WO2006059347A2 (en) * 2004-12-01 2006-06-08 Morepen Laboratories Limited Improved process for preparation of ramipril
US8558023B2 (en) 2010-04-20 2013-10-15 Chiral Quest, Inc. Enantioselective process for cycloalkenyl β-substituted alanines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids

Also Published As

Publication number Publication date
HU191120B (en) 1987-01-28
NO166641C (no) 1991-08-21
ES529272A0 (es) 1984-10-01
DE3468415D1 (en) 1988-02-11
DK41584A (da) 1984-08-01
DK41584D0 (da) 1984-01-30
JPH0517439A (ja) 1993-01-26
IL70830A (en) 1988-02-29
NO840350L (no) 1984-08-01
FI840350A7 (fi) 1984-08-01
HUT34159A (en) 1985-02-28
AU2393384A (en) 1984-08-02
IE840210L (en) 1984-07-31
NZ206980A (en) 1988-05-30
AU566589B2 (en) 1987-10-22
EP0115345B1 (de) 1988-01-07
IE56654B1 (en) 1991-10-23
FI840350A0 (fi) 1984-01-27
KR910001438B1 (ko) 1991-03-07
CA1317067C (en) 1993-04-27
EP0115345A1 (de) 1984-08-08
PT78036B (de) 1986-05-30
PT78036A (de) 1984-02-01
CA1283249C (en) 1991-04-16
ES8500228A1 (es) 1984-10-01
IL70830A0 (en) 1984-04-30
NO166641B (no) 1991-05-13
JPH0788358B2 (ja) 1995-09-27
ES8501759A1 (es) 1984-12-01
DK174386B1 (da) 2003-01-27
FI88153C (fi) 1993-04-13
MA20020A1 (fr) 1984-10-01
FI88153B (fi) 1992-12-31
GR82650B (es) 1985-02-07

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