ES534146A0 - Metodo de preparacion de teofilinas 7-substituidas - Google Patents

Metodo de preparacion de teofilinas 7-substituidas

Info

Publication number: ES534146A0
Authority: ES; Spain
Prior art keywords: stands; formula; image; methyl; straight
Prior art date: 1982-03-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES534146A

Other languages

English (en)

Other versions

ES8505999A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Chinoin Private Co Ltd

Original Assignee

Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-03-12

Filing date

1984-06-29

Publication date

1985-07-01

1984-06-29 Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt

1985-07-01 Publication of ES534146A0 publication Critical patent/ES534146A0/es

1985-07-01 Publication of ES8505999A1 publication Critical patent/ES8505999A1/es

Status Expired legal-status Critical Current

Links

239000001257 hydrogen Substances 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
-1 2-ethoxyethyl Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
125000006704 (C5-C6) cycloalkyl group Chemical group 0.000 abstract 1
125000000579 2,2-diphenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])* 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000004103 aminoalkyl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000005243 carbonyl alkyl group Chemical group 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical class [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
229920002554 vinyl polymer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ES534146A 1982-03-12 1984-06-29 Metodo de preparacion de teofilinas 7-substituidas Expired ES8505999A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU82762A HU190377B (en)	1982-03-12	1982-03-12	Process for preparing theophyllinyl-alkyl-oxadiazoles

Publications (2)

Publication Number	Publication Date
ES534146A0 true ES534146A0 (es)	1985-07-01
ES8505999A1 ES8505999A1 (es)	1985-07-01

Family

ID=10951220

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES520860A Expired ES8504195A1 (es)	1982-03-12	1983-03-12	Procedimiento de preparar teofilinas 7-substituidas.
ES534146A Expired ES8505999A1 (es)	1982-03-12	1984-06-29	Metodo de preparacion de teofilinas 7-substituidas

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ES520860A Expired ES8504195A1 (es)	1982-03-12	1983-03-12	Procedimiento de preparar teofilinas 7-substituidas.

Country Status (17)

Country	Link
US (1)	US4565817A (es)
EP (1)	EP0089028B1 (es)
JP (1)	JPS5910586A (es)
AT (1)	ATE34575T1 (es)
BG (1)	BG60434B2 (es)
DD (1)	DD207377A5 (es)
DE (1)	DE3376749D1 (es)
DK (1)	DK161385C (es)
ES (2)	ES8504195A1 (es)
FI (1)	FI72320C (es)
GR (1)	GR78450B (es)
HU (1)	HU190377B (es)
IL (1)	IL68093A0 (es)
NO (1)	NO159794C (es)
PL (2)	PL138550B1 (es)
SK (1)	SK278001B6 (es)
SU (3)	SU1322981A3 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU190377B (en) *	1982-03-12	1986-08-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing theophyllinyl-alkyl-oxadiazoles
LV5262A3 (lv) *	1986-10-09	1993-10-10	Chinoin Gyogyszer Es Vegyeszet	Oksadiazolilalkilpurina atvasinajumi kam piemit pretklepus aktivitate
HU197574B (en) *	1986-10-09	1989-04-28	Chinoin Gyogyszer Es Vegyeszet	Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances
HU198933B (en) *	1987-11-02	1989-12-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing new xanthine derivatives and pharmaceutical compositions comprising same as active ingredient
HU206884B (en) *	1990-11-22	1993-01-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing purin derivatives and pharmaceutical compositions containing them
US5817662A (en) *	1992-11-09	1998-10-06	Cell Therapeutics, Inc.	Substituted amino alkyl compounds
US5340813A (en) *	1992-11-09	1994-08-23	Cell Therapeutics, Inc.	Substituted aminoalkyl xanthine compounds
WO1994015605A1 (en) *	1993-01-14	1994-07-21	Cell Therapeutics, Inc.	Acetal or ketal substituted therapeutic compounds
US6103730A (en) *	1994-03-24	2000-08-15	Cell Therapeutics, Inc.	Amine substituted compounds
US5807861A (en) *	1994-03-24	1998-09-15	Cell Therapeutics, Inc.	Amine substituted xanthinyl compounds
US5801182A (en) *	1994-03-24	1998-09-01	Cell Therapeutics, Inc.	Amine substituted compounds
US20070215201A1 (en) *	2006-03-17	2007-09-20	Lawrence Curtin	Photovoltaic cell with integral light transmitting waveguide in a ceramic sleeve
CN101801362B (zh) *	2007-06-22	2014-01-22	海德拉生物科学公司	用于治疗病症的方法和组合物
WO2009140517A1 (en)	2008-05-14	2009-11-19	Hydra Biosciences, Inc.	Compounds and compositions for treating chemical warfare agent-induced injuries

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1063323B (de) *	1957-06-29	1959-08-13	Willi Keil	Zentrifugalgeblaese oder -pumpe
NL302339A (es) *	1963-03-22
DE1620576A1 (de) *	1966-11-25	1970-02-26	Troponwerke Dinklage & Co	Verfahren zur Herstellung von Theophyllin- und Theobrominverbindungen
DE1670497C3 (de) *	1967-06-06	1973-12-20	Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt, Budapest	Isochinohnderivate und Verfahren zu deren Herstellung
IT1156913B (it) *	1978-03-13	1987-02-04	Geymonat Sud Spa	Composto ad attivita farmaceutica e procedimento per la sua preparazione
EP0011399A1 (en) *	1978-11-11	1980-05-28	FISONS plc	N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
IT1195267B (it) *	1980-04-15	1988-10-12	Abc Ist Biolog Chem Spa	Derivati teofillinmetildiossolanici,procedimento per la loro preparazione e relative composizioni farmaceutiche
HU190377B (en) *	1982-03-12	1986-08-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing theophyllinyl-alkyl-oxadiazoles

1982
- 1982-03-12 HU HU82762A patent/HU190377B/hu not_active IP Right Cessation
1983
- 1983-03-09 IL IL68093A patent/IL68093A0/xx not_active IP Right Cessation
- 1983-03-10 NO NO830843A patent/NO159794C/no unknown
- 1983-03-10 GR GR70757A patent/GR78450B/el unknown
- 1983-03-11 DE DE8383102422T patent/DE3376749D1/de not_active Expired
- 1983-03-11 FI FI830831A patent/FI72320C/fi not_active IP Right Cessation
- 1983-03-11 AT AT83102422T patent/ATE34575T1/de active
- 1983-03-11 JP JP58039338A patent/JPS5910586A/ja active Granted
- 1983-03-11 EP EP83102422A patent/EP0089028B1/de not_active Expired
- 1983-03-11 US US06/474,227 patent/US4565817A/en not_active Expired - Lifetime
- 1983-03-11 SU SU833568848A patent/SU1322981A3/ru active
- 1983-03-11 SK SK1701-83A patent/SK278001B6/sk unknown
- 1983-03-11 DK DK118083A patent/DK161385C/da active
- 1983-03-11 DD DD83248727A patent/DD207377A5/de not_active IP Right Cessation
- 1983-03-11 PL PL1983240990A patent/PL138550B1/pl unknown
- 1983-03-11 PL PL1983249225A patent/PL138857B1/pl unknown
- 1983-03-12 ES ES520860A patent/ES8504195A1/es not_active Expired
- 1983-10-19 SU SU833654725A patent/SU1344756A1/ru active
1984
- 1984-02-23 SU SU843703572A patent/SU1297729A3/ru active
- 1984-06-29 ES ES534146A patent/ES8505999A1/es not_active Expired
1993
- 1993-12-02 BG BG098262A patent/BG60434B2/bg unknown

Also Published As

Publication number	Publication date
ES8505999A1 (es)	1985-07-01
PL249225A1 (en)	1985-06-04
EP0089028A1 (de)	1983-09-21
FI830831L (fi)	1983-09-13
GR78450B (es)	1984-09-27
EP0089028B1 (de)	1988-05-25
PL138857B1 (en)	1986-11-29
FI830831A0 (fi)	1983-03-11
HU190377B (en)	1986-08-28
ATE34575T1 (de)	1988-06-15
ES520860A0 (es)	1985-04-16
DK118083A (da)	1983-09-13
FI72320C (fi)	1987-05-11
FI72320B (fi)	1987-01-30
SU1344756A1 (ru)	1987-10-15
NO159794C (no)	1989-02-08
DD207377A5 (de)	1984-02-29
NO830843L (no)	1983-09-13
JPH0532395B2 (es)	1993-05-14
SK170183A3 (en)	1995-09-13
SK278001B6 (sk)	1995-09-13
BG60434B2 (bg)	1995-03-31
NO159794B (no)	1988-10-31
US4565817A (en)	1986-01-21
JPS5910586A (ja)	1984-01-20
SU1322981A3 (ru)	1987-07-07
DE3376749D1 (en)	1988-06-30
SU1297729A3 (ru)	1987-03-15
DK161385C (da)	1991-12-16
ES8504195A1 (es)	1985-04-16
PL240990A1 (en)	1985-01-02
DK161385B (da)	1991-07-01
DK118083D0 (da)	1983-03-11
DE3376749T2 (es)	1988-06-30
PL138550B1 (en)	1986-10-31
IL68093A0 (en)	1983-06-15

Legal Events

Date	Code	Title	Description
2001-11-16	FD1A	Patent lapsed	Effective date: 20010910

Publication	Publication Date	Title
ES520860A0 (es)	1985-04-16	Procedimiento de preparar teofilinas 7-substituidas.
ES8707223A1 (es)	1987-07-16	Un procedimiento para la preparacion de derivados de benzotiazol y benzotiofen.
AU540916B2 (en)	1984-12-06	3,1 benzoxazin-2-ones
HUP9700595A1 (hu)	2000-08-28	Fluor-alkil- és fluor-alkoxicsoporttal helyettesített heterociklikus bradikinin-antagonisták, eljárás ezek előállítására, valamint ezek alkalmazása
DE69105572D1 (de)	1995-01-19	4-Phenylphthalazin-Derivate.
DK400781A (da)	1982-03-11	Fremgangsmaade til fremstilling af 2-(1,4-benzodioxan-2-ylalkyl) imidazoler
NO890440L (no)	1990-01-15	Fremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater.
FI883483A0 (fi)	1988-07-22	Piperidinderivat, deras framstaellning och anvaendning vid terapi.
TW225989B (es)	1994-07-01
IL68032A (en)	1986-01-31	Substituted 4-phenyl-4,5,6,7-tetrahydro-thieno(2,3-c)-pyridines and salts thereof,their preparation and pharmaceutical compositions containing them
ATE43575T1 (de)	1989-06-15	(4.2.0>-bicyclooctanderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DK0379414T3 (da)	1994-02-14	Derivater af 1,8-benzonaphthyridin og fremstilling deraf
ES8307798A1 (es)	1983-08-01	Un procedimiento para la preparacion de derivados de piperazilmetil-4-dibenzofuranona, o, dibenzofuranol.
MX9804482A (es)	1998-12-31	Quinolinas y quinazolinas utiles en terapias.
DE3467297D1 (en)	1987-12-17	Benzobicyclononane amino derivatives with anticonvulsive properties