ES540042A0 - Procedimiento para la preparacion de 1-(2,4'-difluorobenci- dril-4-(3,4-dimetoxicinamil)-piperacina - Google Patents

Procedimiento para la preparacion de 1-(2,4'-difluorobenci- dril-4-(3,4-dimetoxicinamil)-piperacina

Info

Publication number
ES540042A0
ES540042A0 ES540042A ES540042A ES540042A0 ES 540042 A0 ES540042 A0 ES 540042A0 ES 540042 A ES540042 A ES 540042A ES 540042 A ES540042 A ES 540042A ES 540042 A0 ES540042 A0 ES 540042A0
Authority
ES
Spain
Prior art keywords
preparation
dimetoxicinamil
difluorobenci
piperacine
dril
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES540042A
Other languages
English (en)
Other versions
ES8601176A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PULITZER ITALIANA
Original Assignee
PULITZER ITALIANA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PULITZER ITALIANA filed Critical PULITZER ITALIANA
Publication of ES540042A0 publication Critical patent/ES540042A0/es
Publication of ES8601176A1 publication Critical patent/ES8601176A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
ES540042A 1984-02-02 1985-02-01 Procedimiento para la preparacion de 1-(2,4'-difluorobenci- dril-4-(3,4-dimetoxicinamil)-piperacina Expired ES8601176A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419372A IT1213131B (it) 1984-02-02 1984-02-02 Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche.

Publications (2)

Publication Number Publication Date
ES540042A0 true ES540042A0 (es) 1985-11-01
ES8601176A1 ES8601176A1 (es) 1985-11-01

Family

ID=11157131

Family Applications (1)

Application Number Title Priority Date Filing Date
ES540042A Expired ES8601176A1 (es) 1984-02-02 1985-02-01 Procedimiento para la preparacion de 1-(2,4'-difluorobenci- dril-4-(3,4-dimetoxicinamil)-piperacina

Country Status (5)

Country Link
EP (1) EP0152799B1 (es)
AT (1) ATE30422T1 (es)
DE (2) DE3560830D1 (es)
ES (1) ES8601176A1 (es)
IT (1) IT1213131B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61161272A (ja) * 1985-01-11 1986-07-21 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
US4792553A (en) * 1986-02-04 1988-12-20 Terumo Kabushiki Kaisha Diene derivatives and vasodilators containing the same
US5428037A (en) * 1993-04-09 1995-06-27 Syntex Pharmaceuticals, Ltd. Heterocyclic derivatives in the treatment of Ischaemia and related diseases
CA2153979C (en) * 1993-12-08 2003-10-21 Mark Hellberg Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE33283B1 (en) * 1968-07-02 1974-05-15 Pharmaceutica J Nv N-arallyl-n'-aralkyl piperazines and pharmaceutical compositions thereof
BE790971A (fr) * 1971-11-09 1973-05-07 Janssen Pharmaceutica Nv Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen

Also Published As

Publication number Publication date
IT8419372A0 (it) 1984-02-02
EP0152799B1 (en) 1987-10-28
DE152799T1 (de) 1986-01-02
ATE30422T1 (de) 1987-11-15
EP0152799A1 (en) 1985-08-28
DE3560830D1 (en) 1987-12-03
IT1213131B (it) 1989-12-14
ES8601176A1 (es) 1985-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303