ES548357A0 - Procedimiento para preparar derivados de n-(adamantil-1)-pirrolidon-5-carboxamida-2. - Google Patents

Procedimiento para preparar derivados de n-(adamantil-1)-pirrolidon-5-carboxamida-2.

Info

Publication number
ES548357A0
ES548357A0 ES548357A ES548357A ES548357A0 ES 548357 A0 ES548357 A0 ES 548357A0 ES 548357 A ES548357 A ES 548357A ES 548357 A ES548357 A ES 548357A ES 548357 A0 ES548357 A0 ES 548357A0
Authority
ES
Spain
Prior art keywords
pirrolidon
adamantil
carboxamida
procedure
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES548357A
Other languages
English (en)
Other versions
ES8702888A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Panmedica SA
Original Assignee
Panmedica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panmedica SA filed Critical Panmedica SA
Publication of ES548357A0 publication Critical patent/ES548357A0/es
Publication of ES8702888A1 publication Critical patent/ES8702888A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
ES548357A 1984-10-31 1985-10-30 Procedimiento para preparar derivados de n-(adamantil-1)-pirrolidon-5-carboxamida-2. Expired ES8702888A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8416656A FR2572399B1 (fr) 1984-10-31 1984-10-31 Nouveaux derives de l'adamantanamine, leurs procedes de preparation et medicaments les contenant

Publications (2)

Publication Number Publication Date
ES548357A0 true ES548357A0 (es) 1987-01-16
ES8702888A1 ES8702888A1 (es) 1987-01-16

Family

ID=9309181

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548357A Expired ES8702888A1 (es) 1984-10-31 1985-10-30 Procedimiento para preparar derivados de n-(adamantil-1)-pirrolidon-5-carboxamida-2.

Country Status (10)

Country Link
US (1) US4661512A (es)
EP (1) EP0187052B1 (es)
JP (1) JPS61109766A (es)
KR (1) KR920003837B1 (es)
AT (1) ATE49957T1 (es)
AU (1) AU583543B2 (es)
DE (1) DE3575715D1 (es)
ES (1) ES8702888A1 (es)
FR (1) FR2572399B1 (es)
ZA (1) ZA858169B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3609152A1 (de) * 1986-03-19 1987-09-24 Bayer Ag Verfahren zur herstellung des (-)-antipoden des (e)-1-cyclohexyl-4,4-dimethyl- 3-hydroxy-2-(1,2,4-triazol-1-yl)-pent-1-ens
FR2603888B1 (fr) * 1986-09-16 1990-12-21 Panmedica Sa Esters d'amino acides du trimethyl cyclohexanol, procede de preparation et utilisation comme medicaments
US5236946A (en) * 1986-09-16 1993-08-17 Panmedica S.A. Amino acid esters of cycloaliphatic alcohols and their use in treating lipemic disorders
DE69130489T2 (de) * 1990-02-28 1999-05-12 Teikoku Seiyaku K.K., Kagawa Physiologisch aktive Substanz die fähig ist Biomembran zu permeieren
US5652335A (en) * 1990-02-28 1997-07-29 Teikoku Seiyaku Kabushiki Kaisha Physiologically active substance well capable of permeating biomembrane
WO1995020951A1 (en) * 1994-02-01 1995-08-10 Board Of Regents Of The University Of Nebraska Polymeric adamantane analogues
US5880154A (en) * 1994-02-01 1999-03-09 The Board Of Regents Of The University Of Nebraska Polymeric adamantane analogues
WO1997003057A1 (en) * 1995-07-07 1997-01-30 Durham Pharmaceuticals, Llc Cyclic amides and derivatives thereof
DE69805909T2 (de) * 1997-04-10 2002-09-26 Pfizer Inc., New York Fluorosubstituierte Adamantan-Derivate
CO5150173A1 (es) * 1998-12-10 2002-04-29 Novartis Ag Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv
US6808716B2 (en) * 1999-01-08 2004-10-26 Ruey J. Yu N-acetylamino acids, related N-acetyl compounds and their topical use
US6159485A (en) 1999-01-08 2000-12-12 Yugenic Limited Partnership N-acetyl aldosamines, n-acetylamino acids and related n-acetyl compounds and their topical use
CN100402026C (zh) * 2002-06-03 2008-07-16 诺瓦提斯公司 取代的氰基吡咯烷和含有它们的组合制剂用于治疗高脂血症和相关疾病的用途
WO2005108359A1 (en) * 2004-05-06 2005-11-17 Pfizer Inc. Novel compounds of proline and morpholine derivatives
JP2007102047A (ja) * 2005-10-07 2007-04-19 Dainippon Printing Co Ltd 商品管理用タグ

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3152180A (en) * 1960-08-25 1964-10-06 Studiengesellschaft Kohle Mbh Process for the production of nu-tert-alkyl amides and, if desired, nu-tert. alkyl amines
FR2622M (fr) * 1962-12-29 1964-06-29 Mundipharma Ag Nouveaux composés thérapeutiques.
US3345399A (en) * 1965-01-21 1967-10-03 Lilly Co Eli Carbamate esters of adamantane, mono-and di-methyladamantane and homoadamantane
US3374244A (en) * 1966-06-13 1968-03-19 Searle & Co N-(dialkylaminoalkyl)adamantanecarboxamides and related compounds
GB1150851A (en) * 1966-06-15 1969-05-07 Tanabe Seiyaku Co Improvements in or relating to the production of Optically Active N-Acylprolines and Prolines
US3682922A (en) * 1969-01-16 1972-08-08 Searle & Co N-acyl-n-{8 (n{40 ,n{40 -disubstituted amino)-alkyl{9 -1-adamantylmethylamines
BE754823A (fr) * 1969-08-13 1971-01-18 Merz & Co Derives de l'amonioadamantane et leur procede de preparation
JPS5581857A (en) * 1978-12-15 1980-06-20 Kyowa Hakko Kogyo Co Ltd Modifier of citrus fruit
US4273704A (en) * 1979-12-03 1981-06-16 G. D. Searle & Co. N-Adamantane-substituted tetrapeptide amides
US4296110A (en) * 1980-10-28 1981-10-20 E. I. Du Pont De Nemours And Company Antihypertensive I-substituted cyclic lactam-2-carboxylic acids
JPS5865269A (ja) * 1981-10-12 1983-04-18 Suntory Ltd ４置換（２ｓ，３ｓ，４ｓ）−２−カルボキシピロリジン−３−酢酸およびそのエステル
US4448972A (en) * 1982-02-22 1984-05-15 Smithkline Beckman Corporation Adamantyl containing intermediates
CS231221B1 (en) * 1982-06-29 1984-10-15 Martin Flegel L-alanyl-d-isoglutamine adamantylamide

Also Published As

Publication number Publication date
FR2572399A1 (fr) 1986-05-02
EP0187052A1 (fr) 1986-07-09
ES8702888A1 (es) 1987-01-16
ZA858169B (en) 1986-06-25
FR2572399B1 (fr) 1987-01-16
JPS61109766A (ja) 1986-05-28
US4661512A (en) 1987-04-28
AU4884685A (en) 1986-05-08
AU583543B2 (en) 1989-05-04
KR860003219A (ko) 1986-05-21
DE3575715D1 (de) 1990-03-08
KR920003837B1 (ko) 1992-05-15
ATE49957T1 (de) 1990-02-15
EP0187052B1 (fr) 1990-01-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519