ES556370A0 - Procedimiento para la obtencion de acidos 4-quinolon-3-carboxilicos 1,8-puenteados - Google Patents

Procedimiento para la obtencion de acidos 4-quinolon-3-carboxilicos 1,8-puenteados

Info

Publication number
ES556370A0
ES556370A0 ES556370A ES556370A ES556370A0 ES 556370 A0 ES556370 A0 ES 556370A0 ES 556370 A ES556370 A ES 556370A ES 556370 A ES556370 A ES 556370A ES 556370 A0 ES556370 A0 ES 556370A0
Authority
ES
Spain
Prior art keywords
quinolon
bridged
procedure
obtaining
carboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES556370A
Other languages
English (en)
Other versions
ES8801210A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES556370A0 publication Critical patent/ES556370A0/es
Publication of ES8801210A1 publication Critical patent/ES8801210A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES556370A 1985-06-22 1986-06-20 Procedimiento para la obtencion de acidos 4-quinolon-3-carboxilicos 1,8-puenteados Expired ES8801210A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853522406 DE3522406A1 (de) 1985-06-22 1985-06-22 Verfahren zur herstellung von 1,8-verbrueckten 4-chinolon-3-carbonsaeuren

Publications (2)

Publication Number Publication Date
ES556370A0 true ES556370A0 (es) 1987-12-16
ES8801210A1 ES8801210A1 (es) 1987-12-16

Family

ID=6273930

Family Applications (2)

Application Number Title Priority Date Filing Date
ES556370A Expired ES8801210A1 (es) 1985-06-22 1986-06-20 Procedimiento para la obtencion de acidos 4-quinolon-3-carboxilicos 1,8-puenteados
ES557698A Expired ES8801920A1 (es) 1985-06-22 1987-08-28 Procedimiento para la obtencio de enaminas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557698A Expired ES8801920A1 (es) 1985-06-22 1987-08-28 Procedimiento para la obtencio de enaminas

Country Status (6)

Country Link
US (3) US4762831A (es)
EP (1) EP0206101A1 (es)
JP (1) JPS62452A (es)
KR (1) KR880000439A (es)
DE (1) DE3522406A1 (es)
ES (2) ES8801210A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522405A1 (de) * 1985-06-22 1987-01-02 Bayer Ag 1,8-verbrueckte 4-chinolon-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel und ihre verwendung zur herstellung von arzneimitteln
US5237060A (en) * 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
EP0286802B1 (en) * 1987-02-26 1993-06-23 Rohto Pharmaceutical Co., Ltd. Use of ofloxacin in treating or preventing locally periodontal disease
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
JPH0826029B2 (ja) * 1987-12-22 1996-03-13 第一製薬株式会社 魚類感染症の予防・治療剤
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US5585491A (en) * 1988-01-25 1996-12-17 Otsuka Pharmaceutical Co., Ltd. Antibacterial agents
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
DE3902079A1 (de) * 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
US4996355A (en) * 1989-04-14 1991-02-26 Mallinckrodt, Inc. Novel intermediates for the production of 2,4,5-trifluorobenzoyl fluoride
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
US5359066A (en) * 1991-02-28 1994-10-25 Wakunaga Pharmaceutical Co., Ltd. Certain tricyclic pyrido[3,2,1-ij]cinnoline-8-carboxylates, useful as antimicrobial agents
AU674542B2 (en) * 1992-10-07 1997-01-02 Derivados Del Etilo, S.A. Process for obtaining benzoxazines useful for the synthesis of ofloxacin, levofloxacin and derivatives thereof
ES2055656B1 (es) * 1992-10-07 1995-11-16 Etilo Derivados Procedimiento para la obtencion de benzoxazinas utiles para sintesis de ofloxacina, levofloxacina y derivados.
US5644056A (en) * 1995-06-07 1997-07-01 Hoechst Celanese Corporation Method of preparing 7,8-difluoro-2,3-dihydro-3-methyl-4H-1, 4-benzoxazine
KR100309871B1 (ko) 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
JPWO2006009143A1 (ja) * 2004-07-21 2008-05-01 杏林製薬株式会社 （３ｓ）−３−ヒドロキシメチル−７−オキソピリドベンゾオキサジン−６−カルボン酸エステルの製造方法
ATE464289T1 (de) * 2005-11-16 2010-04-15 Hoffmann La Roche Neues verfahren zur herstellung von thoc
AU2007225088B2 (en) 2006-03-13 2012-09-13 Kyorin Pharmaceutical Co., Ltd Aminoquinolones as GSK-3 inhibitors
KR101597841B1 (ko) 2007-09-12 2016-02-26 교린 세이야꾸 가부시키 가이샤 Ｇｓｋ-３ 억제제로서의 스피로시클릭 아미노퀴놀론
CA2755120C (en) 2009-03-11 2017-05-16 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones as gsk-3 inhibitors
CN103183684B (zh) * 2011-12-29 2015-11-18 杭州师范大学 一种喹喏酮内酯化合物及其制备方法和应用
CN105037388A (zh) * 2015-08-28 2015-11-11 安徽环球药业股份有限公司 一种安妥沙星的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD62321A (es) *
DE62321C (de) * O. MEURER in Köln a. Rh., Mühlenbach 54—58 Neuerung an einem Bodenbelag für Malztennen u. dergl
NL7101049A (es) * 1970-01-28 1971-07-30
US3883522A (en) * 1974-02-11 1975-05-13 Riker Laboratories Inc Substituted pyrido(1,2,3-de)-1,4-benzoxazines
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
SE440354B (sv) * 1981-02-19 1985-07-29 Kyorin Seiyaku Kk Kinolinkarboxylsyraderivat
US4499270A (en) * 1981-04-16 1985-02-12 Riker Laboratories, Inc. Substituted pyridoquinoxaline-6-carboxylic acids and derivatives thereof
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
DE3416120A1 (de) * 1984-04-30 1985-10-31 Henkel KGaA, 4000 Düsseldorf Benzoylalanine und ihre verwendung als korrosionsinhibitoren fuer waessrige systeme
US4571346A (en) * 1984-08-01 1986-02-18 General Foods Corporation Method for producing cold-water soluble gelatin dessert mixes and products therefrom
US4777253A (en) * 1986-04-25 1988-10-11 Abbott Laboratories Process for preparation of racemate and optically active ofloxacin and related derivatives

Also Published As

Publication number Publication date
KR880000439A (ko) 1988-03-25
ES557698A0 (es) 1988-03-01
US4958045A (en) 1990-09-18
JPS62452A (ja) 1987-01-06
US4859773A (en) 1989-08-22
DE3522406A1 (de) 1987-01-02
US4762831A (en) 1988-08-09
EP0206101A1 (de) 1986-12-30
ES8801920A1 (es) 1988-03-01
ES8801210A1 (es) 1987-12-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401