ES557241A0 - Procedimiento para preparar nuevos 2-aril-imidazoles - Google Patents
Procedimiento para preparar nuevos 2-aril-imidazolesInfo
- Publication number
- ES557241A0 ES557241A0 ES557241A ES557241A ES557241A0 ES 557241 A0 ES557241 A0 ES 557241A0 ES 557241 A ES557241 A ES 557241A ES 557241 A ES557241 A ES 557241A ES 557241 A0 ES557241 A0 ES 557241A0
- Authority
- ES
- Spain
- Prior art keywords
- imidazoles
- aryl
- procedure
- preparing new
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853522230 DE3522230A1 (de) | 1985-06-21 | 1985-06-21 | Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES557241A0 true ES557241A0 (es) | 1987-05-16 |
| ES8705864A1 ES8705864A1 (es) | 1987-05-16 |
Family
ID=6273829
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES556338A Expired ES8800907A1 (es) | 1985-06-21 | 1986-06-20 | Procedimiento para preparar nuevos 2-arilimidazoles |
| ES557241A Expired ES8705864A1 (es) | 1985-06-21 | 1986-12-04 | Procedimiento para preparar nuevos 2-aril-imidazoles |
| ES557240A Expired ES8705863A1 (es) | 1985-06-21 | 1986-12-04 | Procedimiento para preparar nuevos 2-arilimidazoles |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES556338A Expired ES8800907A1 (es) | 1985-06-21 | 1986-06-20 | Procedimiento para preparar nuevos 2-arilimidazoles |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES557240A Expired ES8705863A1 (es) | 1985-06-21 | 1986-12-04 | Procedimiento para preparar nuevos 2-arilimidazoles |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0209707A3 (es) |
| JP (1) | JPS62471A (es) |
| AU (1) | AU5893286A (es) |
| DE (1) | DE3522230A1 (es) |
| DK (1) | DK290986A (es) |
| ES (3) | ES8800907A1 (es) |
| FI (1) | FI862623A7 (es) |
| GR (1) | GR861583B (es) |
| HU (1) | HUT42452A (es) |
| NO (1) | NO862477L (es) |
| PT (1) | PT82789B (es) |
| ZA (1) | ZA864602B (es) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU85544A1 (fr) * | 1984-09-19 | 1986-04-03 | Cird | Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique |
| GB8510758D0 (en) * | 1985-04-27 | 1985-06-05 | Wellcome Found | Compounds |
| DE3634066A1 (de) * | 1986-10-07 | 1988-04-21 | Boehringer Mannheim Gmbh | Neue 5-alkylbenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
| EP0322149A2 (en) * | 1987-12-22 | 1989-06-28 | Eli Lilly And Company | Hydrates of an inotropic agent |
| GB8804016D0 (en) * | 1988-02-22 | 1988-03-23 | Boots Co Plc | Therapeutic agents |
| IL94390A (en) * | 1989-05-30 | 1996-03-31 | Merck & Co Inc | The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them |
| US5064825A (en) * | 1989-06-01 | 1991-11-12 | Merck & Co., Inc. | Angiotensin ii antagonists |
| JPH06759B2 (ja) * | 1989-09-22 | 1994-01-05 | ファイザー製薬株式会社 | 新規なベンゾイミダゾール化合物 |
| US5208240A (en) * | 1991-03-12 | 1993-05-04 | Merrell Dow Pharmaceuticals Inc. | 8-substituted purines as selective adenosine receptor agents |
| JPH05112533A (ja) * | 1991-05-08 | 1993-05-07 | Upjohn Co:The | イミダゾベンゾキノン類およびこれを有効成分とする高血圧・鬱血性心不全の予防・治療剤 |
| US5506361A (en) * | 1991-05-08 | 1996-04-09 | Theupjohn Company | Imidazobenzoquinones and composition for preventing or treating hypertension or congestive heart failure containing the same |
| US5821258A (en) * | 1994-12-27 | 1998-10-13 | Mitsui Chemicals, Inc. | Phenylbenzimidazole derivatives |
| DK0841924T3 (da) * | 1995-08-02 | 2003-02-10 | Univ Newcastle Ventures Ltd | Benzimidazolforbindelser |
| TR200101239T2 (tr) * | 1998-11-03 | 2001-11-21 | Basf Aktiengesellschaft | İkameli-2-fenilbenzimidazoller, üretimleri ve kullanımları |
| JP2002529537A (ja) * | 1998-11-17 | 2002-09-10 | ビーエーエスエフ アクチェンゲゼルシャフト | ２−フェニルベンズイミダゾールおよび２−フェニルインドール、その製造方法ならびに使用 |
| DE19918211A1 (de) * | 1999-04-22 | 2000-10-26 | Basf Ag | Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung |
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| EP2335700A1 (en) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
| JP4637481B2 (ja) | 2001-10-19 | 2011-02-23 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | Ｃｄｓ１／ｃｈｋ２阻害剤および癌治療における化学療法または放射線療法の補助剤としての２−フェニルベンズイミダゾールおよびイミダゾ−［４，５］−ピリジン |
| PT1492773E (pt) * | 2002-04-05 | 2009-05-07 | Cadila Healthcare Ltd | Compostos de 4-(heterociclilo)-benzenossulfoximinapara o tratamento da inflamação |
| AU2002368133A1 (en) * | 2002-07-29 | 2004-02-16 | Shizuoka Coffein Co., Ltd. | 1,3-azole derivative and medicinal composition containing the derivative for treatment for thombosis |
| US7098231B2 (en) | 2003-01-22 | 2006-08-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| US7223785B2 (en) | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| JP4726235B2 (ja) | 2003-04-17 | 2011-07-20 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 癌の処置のためのチェックポイントキナーゼｃｄｓ１（ｃｈｋ２）インヒビターとしての２−フェニル−ベンズイミダゾールおよび２−フェニル−イミダゾ−‘４，５！−ピリジン誘導体 |
| CN1922174A (zh) | 2004-02-20 | 2007-02-28 | 贝林格尔·英格海姆国际有限公司 | 病毒聚合酶抑制剂 |
| CA2572218C (en) | 2004-06-30 | 2013-06-11 | Janssen Pharmaceutica, N.V. | Aryl-substituted benzimidazole and imidazopyridine ethers as anti-cancer agents |
| US7728026B2 (en) | 2005-04-11 | 2010-06-01 | Abbott Laboratories, Inc. | 2-substituted-1 h-benzimidazile-4-carboxamides are PARP inhibitors |
| TWI375673B (en) | 2005-04-11 | 2012-11-01 | Abbott Lab | 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors |
| CA2618682C (en) | 2005-08-12 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| JP5162465B2 (ja) | 2005-11-15 | 2013-03-13 | アボット・ラボラトリーズ | 置換１ｈ−ベンズイミダゾール−４−カルボキサミド類は強力なｐａｒｐ阻害薬である |
| MX2008014004A (es) | 2006-05-02 | 2008-11-12 | Abbott Lab | 1h-benzimidazol-4-carboxamidas sustituidas son inhibidores de parp potentes. |
| US8067613B2 (en) | 2007-07-16 | 2011-11-29 | Abbott Laboratories | Benzimidazole poly(ADP ribose)polymerase inhibitors |
| WO2010083199A1 (en) | 2009-01-19 | 2010-07-22 | Abbott Laboratories | Benzthiazole inhibitors of poly(adp-ribose)polymerase |
| TW201234965A (en) * | 2010-12-24 | 2012-09-01 | Sumitomo Chemical Co | Fused heterocyclic compound and use for pest control thereof |
| US9573963B2 (en) * | 2013-02-28 | 2017-02-21 | Sumitomo Chemical Company, Limited | Fused heterocyclic compound and pest control applications thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1089853A (en) * | 1965-02-25 | 1967-11-08 | Merck & Co Inc | Substituted benzimidazoles and compositions containing them |
| US3669979A (en) * | 1967-12-14 | 1972-06-13 | Gaf Corp | Novel process for the production of 2-benzothiazolyl-phenol and derivatives thereof employing phosphorus trichloride as a catalyst |
| DE2305339C3 (de) * | 1973-02-03 | 1980-05-08 | Dr. Karl Thomae Gmbh, 7950 Biberach | Imidazo [4,5-b] pyridine, ihre Herstellung und ihre Verwendung als Cardiötonica |
| DE2927988A1 (de) * | 1979-07-11 | 1981-02-05 | Thomae Gmbh Dr K | Neue 8-phenyl-purine, deren herstellung und deren verwendung als arzneimittel |
| DE2927987A1 (de) * | 1979-07-11 | 1981-02-05 | Thomae Gmbh Dr K | Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel |
| DD147317A1 (de) * | 1979-11-23 | 1981-04-01 | Gerald Igel | Einrichtung zur elektrischen stimulation des herzens |
| DE3037464A1 (de) * | 1980-10-03 | 1982-05-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | 6-hydroxy-2-phenyl-imidazo 4,5-b zu pyridine, ihre herstellung und diese sie enthaltende arzneimittel |
| DE3044497A1 (de) * | 1980-11-26 | 1982-06-24 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neues verfahren zur herstellung von imidazo(4,5-b)pyridinen und -pyrimidinen |
| ES8401486A1 (es) * | 1981-11-10 | 1983-12-01 | Wellcome Found | Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina. |
| RO86850B (ro) * | 1982-05-03 | 1985-05-31 | Eli Lilly And Company | Procedeu pentru prepararea unor 2-fenilimidazo [4,5 c] piridine |
| DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| DE3324115A1 (de) * | 1983-07-05 | 1985-01-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| US4515796A (en) * | 1983-09-08 | 1985-05-07 | Eli Lilly And Company | Certain naphthalenyl imidazo compounds and their pharmaceutical use |
| DE3340076A1 (de) * | 1983-11-05 | 1985-05-15 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue purinderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| DE3346575A1 (de) * | 1983-12-23 | 1985-07-04 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue benzimidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| GR850426B (es) * | 1984-02-24 | 1985-06-18 | Lilly Co Eli |
-
1985
- 1985-06-21 DE DE19853522230 patent/DE3522230A1/de not_active Withdrawn
-
1986
- 1986-06-11 EP EP86107969A patent/EP0209707A3/de not_active Withdrawn
- 1986-06-18 GR GR861583A patent/GR861583B/el unknown
- 1986-06-19 PT PT82789A patent/PT82789B/pt unknown
- 1986-06-19 FI FI862623A patent/FI862623A7/fi not_active IP Right Cessation
- 1986-06-20 ZA ZA864602A patent/ZA864602B/xx unknown
- 1986-06-20 DK DK290986A patent/DK290986A/da not_active Application Discontinuation
- 1986-06-20 HU HU862615A patent/HUT42452A/hu unknown
- 1986-06-20 ES ES556338A patent/ES8800907A1/es not_active Expired
- 1986-06-20 JP JP61144658A patent/JPS62471A/ja active Pending
- 1986-06-20 AU AU58932/86A patent/AU5893286A/en not_active Abandoned
- 1986-06-20 NO NO862477A patent/NO862477L/no unknown
- 1986-12-04 ES ES557241A patent/ES8705864A1/es not_active Expired
- 1986-12-04 ES ES557240A patent/ES8705863A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI862623A0 (fi) | 1986-06-19 |
| FI862623A7 (fi) | 1986-12-22 |
| ES557240A0 (es) | 1987-05-16 |
| DE3522230A1 (de) | 1987-01-02 |
| NO862477D0 (no) | 1986-06-20 |
| EP0209707A2 (de) | 1987-01-28 |
| EP0209707A3 (de) | 1989-02-01 |
| PT82789A (de) | 1986-07-01 |
| AU5893286A (en) | 1986-12-24 |
| ES556338A0 (es) | 1987-12-01 |
| ES8705864A1 (es) | 1987-05-16 |
| NO862477L (no) | 1986-12-22 |
| DK290986A (da) | 1986-12-22 |
| DK290986D0 (da) | 1986-06-20 |
| ES8800907A1 (es) | 1987-12-01 |
| GR861583B (en) | 1986-10-21 |
| JPS62471A (ja) | 1987-01-06 |
| ES8705863A1 (es) | 1987-05-16 |
| PT82789B (de) | 1988-05-17 |
| HUT42452A (en) | 1987-07-28 |
| ZA864602B (en) | 1988-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971201 |