ES8101574A1 - Procedimiento de obtencion de un derivado de acido flufena- mico - Google Patents
Procedimiento de obtencion de un derivado de acido flufena- micoInfo
- Publication number
- ES8101574A1 ES8101574A1 ES487369A ES487369A ES8101574A1 ES 8101574 A1 ES8101574 A1 ES 8101574A1 ES 487369 A ES487369 A ES 487369A ES 487369 A ES487369 A ES 487369A ES 8101574 A1 ES8101574 A1 ES 8101574A1
- Authority
- ES
- Spain
- Prior art keywords
- fluffenamic
- translation
- procedure
- obtaining
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- DHXVGJBLRPWPCS-UHFFFAOYSA-N Tetrahydropyran Chemical compound C1CCOCC1 DHXVGJBLRPWPCS-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229940067594 flufenamate Drugs 0.000 abstract 1
- LPEPZBJOKDYZAD-UHFFFAOYSA-N flufenamic acid Chemical compound OC(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1 LPEPZBJOKDYZAD-UHFFFAOYSA-N 0.000 abstract 1
- 159000000011 group IA salts Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE 2-(2-HIDROXIETOXI) ETIL-(N-ALFA,ALFA,ALFA-TRIFLUORO-M-TOLIL)ANTRANILATO. CONSISTE EN: 1) REACCION DE UNA SAL ALCALINA DE ACIDO FLUFENAMICO CON 2-(2-CLOROETOXI) ETOXI-TETRAHIDROPIRANO, EN PRESENCIA DE DIMETILFORMAMIDA A TEMPERATURA DE EBULLICION DEL DISOLVENTE Y DURANTE UN TIEMPO DE 2 A 8 HORAS. SE OBTIENE FLUFENAMATO DE 2-(2-ETOXI) ETOXI TETRAHIDROPIRANO Y UN CLORURO ALCALINO. 2) HIDROLISIS DEL RESTO TETRAHIDROPIRANO EN MEDIO ALCOHOLICO-ACIDO CLORHIDRICO A TEMPERATURA AMBIENTE. SE OBTIENE UN PRODUCTO VISCOSO CASI INCOLORO, NO CRISTALIZABLE, CUYO PUNTO DE EBULLICION ES DE 130-135GC A 10 ELEVADO A -3 MMHG. ANTIINFLAMATORIO ANTIALGICO.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES487369A ES8101574A1 (es) | 1979-12-28 | 1979-12-28 | Procedimiento de obtencion de un derivado de acido flufena- mico |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES487369A ES8101574A1 (es) | 1979-12-28 | 1979-12-28 | Procedimiento de obtencion de un derivado de acido flufena- mico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES487369A0 ES487369A0 (es) | 1980-12-16 |
| ES8101574A1 true ES8101574A1 (es) | 1980-12-16 |
Family
ID=8479540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES487369A Expired ES8101574A1 (es) | 1979-12-28 | 1979-12-28 | Procedimiento de obtencion de un derivado de acido flufena- mico |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8101574A1 (es) |
-
1979
- 1979-12-28 ES ES487369A patent/ES8101574A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES487369A0 (es) | 1980-12-16 |
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