ES8104265A1 - Un procedimiento para la preparacion de nuevas bencenosulfi-namidas - Google Patents

Un procedimiento para la preparacion de nuevas bencenosulfi-namidas

Info

Publication number
ES8104265A1
ES8104265A1 ES489856A ES489856A ES8104265A1 ES 8104265 A1 ES8104265 A1 ES 8104265A1 ES 489856 A ES489856 A ES 489856A ES 489856 A ES489856 A ES 489856A ES 8104265 A1 ES8104265 A1 ES 8104265A1
Authority
ES
Spain
Prior art keywords
benzenesulfinamides
preparation
medicaments containing
phenyl
loweralkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES489856A
Other languages
English (en)
Other versions
ES489856A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8104265A1 publication Critical patent/ES8104265A1/es
Publication of ES489856A0 publication Critical patent/ES489856A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE BENCENOSULFINAMIDAS DE FORMULA: *FORMULA* DONDE R ES PIRIDILO, FENILO O FENILO SUSTITUIDO POR HALOGENO, ALCOHILO INFERIOR, ALCOXI INFERIOR O TRIFLUORMETILO. CONSISTE EN HACER REACCIONAR UNA PIPERAZINA N-SUSTITUIDA DE FORMULA (II): CON UN HALOGENURO DE FENILSULFINILO DE FORMULA (III): *FORMULA* DONDE X ES BROMO O CLORO *FORMULA* ESTOS COMPUESTOS PRESENTAN PROPIEDADES ANTIHIPERTENSORAS.
ES489856A 1979-03-29 1980-03-24 Un procedimiento para la preparacion de nuevas bencenosulfi-namidas Granted ES489856A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/024,930 US4425342A (en) 1979-03-29 1979-03-29 1-(Substituted) piperazine-4-benzenesulfinamides, compositions and method of use

Publications (2)

Publication Number Publication Date
ES8104265A1 true ES8104265A1 (es) 1981-04-16
ES489856A0 ES489856A0 (es) 1981-04-16

Family

ID=21823092

Family Applications (1)

Application Number Title Priority Date Filing Date
ES489856A Granted ES489856A0 (es) 1979-03-29 1980-03-24 Un procedimiento para la preparacion de nuevas bencenosulfi-namidas

Country Status (7)

Country Link
US (1) US4425342A (es)
EP (1) EP0017079A1 (es)
JP (1) JPS55130958A (es)
AU (1) AU5693280A (es)
CA (1) CA1136627A (es)
ES (1) ES489856A0 (es)
ZA (1) ZA801868B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8424979D0 (en) * 1984-10-03 1984-11-07 Wyeth John & Brother Ltd Benzenesulphonamide derivatives
US4857644A (en) * 1988-06-09 1989-08-15 American Home Products Corporation Aryl sulfonopiperazines as anti-inflammatory agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3464971A (en) 1965-10-22 1969-09-02 Eastman Kodak Co Monoazo compounds containing a piperazine type ring substituted by an organo sulfonyl group
US3506649A (en) 1967-08-02 1970-04-14 American Home Prod 1 - phenylsulfonyl - 2 - hydroxy - 4 - substituted - piperazines and derivatives thereof
US3980787A (en) 1975-08-25 1976-09-14 American Hoechst Corporation 3-Phenylspiro[isobenzofuran-1,4'-piperidine]sulfenamides and derivatives
US4015004A (en) * 1975-08-26 1977-03-29 American Hoechst Corporation Phenylsulfenylpiperazines

Also Published As

Publication number Publication date
US4425342A (en) 1984-01-10
JPS55130958A (en) 1980-10-11
AU5693280A (en) 1980-10-02
ZA801868B (en) 1981-04-29
CA1136627A (en) 1982-11-30
EP0017079A1 (en) 1980-10-15
ES489856A0 (es) 1981-04-16

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