ES8200876A1 - Procedimiento para preparar ureas - Google Patents
Procedimiento para preparar ureasInfo
- Publication number
- ES8200876A1 ES8200876A1 ES497805A ES497805A ES8200876A1 ES 8200876 A1 ES8200876 A1 ES 8200876A1 ES 497805 A ES497805 A ES 497805A ES 497805 A ES497805 A ES 497805A ES 8200876 A1 ES8200876 A1 ES 8200876A1
- Authority
- ES
- Spain
- Prior art keywords
- congeners
- azido
- ethoxyethyl
- pyrimidinyl
- acetamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XIVXCUPDKMCGCX-UHFFFAOYSA-N N-[4-azido-5-(2-ethoxyethyl)-6-phenylpyrimidin-2-yl]acetamide Chemical compound CCOCCC1=C(N=[N+]=[N-])N=C(NC(C)=O)N=C1C1=CC=CC=C1 XIVXCUPDKMCGCX-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000039 congener Substances 0.000 title abstract 2
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UREAS, DE FORMULA ESTRUCTURAL (I), DONDE AM REPRESENTA (LOXOALQUIL)AMINO O BIS-(ALCOXICARBONIL)AMINO, EN DONDE CADA UNO DE LOS CONSTITUYENTES OXOALQUILOS, ALQUILOS Y ALCOXIS CONTIENEN MENOS DE CINCO ATOMOS DE CARBONO. CONSISTE EN HACER REACCIONAR COMPUESTOS 2-AMINOPIRIMIDINAS DE FORMULA ESTRUCTURAL (II) CON ISOCIANATOALCANOS EN PRESENCIA DE PIRIDINA Y A UNA TEMPERATURA DE 25 GRADOS APROXIMADAMENTE. DE USO EN FARMACIA COMO DIURETICOS O COMBINADOS CON UNO O MAS COADYUVANTES CON FINES TERAPEUTICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/028,034 US4205169A (en) | 1979-04-09 | 1979-04-09 | N-[4-Azido-5-(2-ethoxyethyl)-6-phenyl-2-pyrimidinyl]acetamide and congeners |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES497805A0 ES497805A0 (es) | 1981-11-16 |
| ES8200876A1 true ES8200876A1 (es) | 1981-11-16 |
Family
ID=21841194
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490388A Expired ES8104251A1 (es) | 1979-04-09 | 1980-04-09 | Procedimiento para preparar acetamidas |
| ES497805A Expired ES8200876A1 (es) | 1979-04-09 | 1980-12-16 | Procedimiento para preparar ureas |
| ES497806A Granted ES497806A0 (es) | 1979-04-09 | 1980-12-16 | Procedimiento para preparar imidodicarbonatos de dialquilo |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490388A Expired ES8104251A1 (es) | 1979-04-09 | 1980-04-09 | Procedimiento para preparar acetamidas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497806A Granted ES497806A0 (es) | 1979-04-09 | 1980-12-16 | Procedimiento para preparar imidodicarbonatos de dialquilo |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4205169A (es) |
| JP (1) | JPS568369A (es) |
| AU (1) | AU5722180A (es) |
| BE (1) | BE882680A (es) |
| CA (1) | CA1130287A (es) |
| DE (1) | DE3013504A1 (es) |
| DK (1) | DK150180A (es) |
| ES (3) | ES8104251A1 (es) |
| FR (1) | FR2453857A1 (es) |
| GB (1) | GB2048860B (es) |
| IT (1) | IT1127438B (es) |
| NL (1) | NL8002061A (es) |
| SE (1) | SE8002608L (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4294830A (en) * | 1980-06-16 | 1981-10-13 | G. D. Searle & Co. | {[[4-Azido-5-(ethoxyethyl)-6-phenyl-2-pyrimidinyl]amino]carbonyl}glycine and esters thereof |
| US4483987A (en) * | 1983-06-20 | 1984-11-20 | G. D. Searle & Co. | 8-Substituted 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines and amides |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3412094A (en) * | 1967-06-21 | 1968-11-19 | Searle & Co | 5-alkyl-2-amino-4-azido-6-phenylpyrimidines and congeners |
| US3455921A (en) * | 1967-09-01 | 1969-07-15 | Searle & Co | 2,4-diazido-6-phenylpyrimidines and intermediates |
-
1979
- 1979-04-09 US US06/028,034 patent/US4205169A/en not_active Expired - Lifetime
-
1980
- 1980-04-08 AU AU57221/80A patent/AU5722180A/en not_active Abandoned
- 1980-04-08 FR FR8007834A patent/FR2453857A1/fr active Pending
- 1980-04-08 DE DE19803013504 patent/DE3013504A1/de not_active Withdrawn
- 1980-04-08 NL NL8002061A patent/NL8002061A/nl not_active Application Discontinuation
- 1980-04-08 IT IT48362/80A patent/IT1127438B/it active
- 1980-04-08 SE SE8002608A patent/SE8002608L/xx not_active Application Discontinuation
- 1980-04-08 BE BE0/200145A patent/BE882680A/fr unknown
- 1980-04-08 CA CA349,342A patent/CA1130287A/en not_active Expired
- 1980-04-08 DK DK150180A patent/DK150180A/da not_active IP Right Cessation
- 1980-04-09 JP JP4670080A patent/JPS568369A/ja active Pending
- 1980-04-09 GB GB8011795A patent/GB2048860B/en not_active Expired
- 1980-04-09 ES ES490388A patent/ES8104251A1/es not_active Expired
- 1980-12-16 ES ES497805A patent/ES8200876A1/es not_active Expired
- 1980-12-16 ES ES497806A patent/ES497806A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| SE8002608L (sv) | 1980-10-10 |
| JPS568369A (en) | 1981-01-28 |
| GB2048860B (en) | 1982-12-15 |
| ES490388A0 (es) | 1981-04-16 |
| IT8048362A0 (it) | 1980-04-08 |
| NL8002061A (nl) | 1980-10-13 |
| IT1127438B (it) | 1986-05-21 |
| AU5722180A (en) | 1980-10-16 |
| CA1130287A (en) | 1982-08-24 |
| GB2048860A (en) | 1980-12-17 |
| ES8200875A1 (es) | 1981-11-16 |
| ES8104251A1 (es) | 1981-04-16 |
| DE3013504A1 (de) | 1980-11-13 |
| BE882680A (fr) | 1980-10-08 |
| ES497805A0 (es) | 1981-11-16 |
| FR2453857A1 (fr) | 1980-11-07 |
| DK150180A (da) | 1980-10-10 |
| US4205169A (en) | 1980-05-27 |
| ES497806A0 (es) | 1981-11-16 |
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