ES8200896A1 - Procedimiento para la obtencion de compuestos de acido aci- lamino-3-cefem-4-carboxilico - Google Patents
Procedimiento para la obtencion de compuestos de acido aci- lamino-3-cefem-4-carboxilicoInfo
- Publication number
- ES8200896A1 ES8200896A1 ES497849A ES497849A ES8200896A1 ES 8200896 A1 ES8200896 A1 ES 8200896A1 ES 497849 A ES497849 A ES 497849A ES 497849 A ES497849 A ES 497849A ES 8200896 A1 ES8200896 A1 ES 8200896A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- index
- compounds
- formula
- nhso2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000005556 thienylene group Chemical group 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTO DE ACIDO ACILAMINO-3-CEFEM-4-CARBOXILICO, DE FORMULA (I), DONDE N ES UN NUMERO ENTERO DE 1 A 4; M ES 0 O 1; X SIGNIFICA OZIGENO, AZUFRE O EL GRUPO -NH-;W SIGNIFICA UN GRUPO -CO-, -CO-NHSO2- O -SO2NH-CO-; A SIGNIFICA FENILO, TIENILO O FURILENO; Z SIGNIFICA OXIGENO O AZUFRE; YSIGNIFICA ALQUILENO INFERIOR; K ES 1 O 2; R4 SIGNIFICA HIDROGENO, UN RESTO ALIFATICO INFERIOR O CICLOALIFATICO; R1 SIGNIFICA HIDROGENO, ALQUILO INFERIOR, ALCOXI INFERIOR, HALOGENO O UN GRUPO - CH2-R2, DONDE R2 SIGNIFICA UN GRUPO HIDROXI O MERCAPTO; R3 SIGNIFICA HIDROGENO O METOXI, Y LAS SALES DE ADICION, FARMACEUTICAMENTE ACEPTABLES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1128379 | 1979-12-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8200896A1 true ES8200896A1 (es) | 1981-11-16 |
| ES497849A0 ES497849A0 (es) | 1981-11-16 |
Family
ID=4371942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497849A Granted ES497849A0 (es) | 1979-12-19 | 1980-12-17 | Procedimiento para la obtencion de compuestos de acido aci- lamino-3-cefem-4-carboxilico |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4464366A (es) |
| EP (1) | EP0031794A3 (es) |
| JP (1) | JPS56103186A (es) |
| AU (1) | AU6551880A (es) |
| DK (1) | DK540880A (es) |
| ES (1) | ES497849A0 (es) |
| IL (1) | IL61751A0 (es) |
| NZ (1) | NZ195875A (es) |
| ZA (1) | ZA807914B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0059683A3 (de) * | 1981-02-27 | 1982-12-01 | Ciba-Geigy Ag | 7-Acylamido-3-cephem-4-carbonsäureverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren |
| GT200500282A (es) * | 2004-10-12 | 2006-05-04 | Heteroatomos conteniendo compuestos triciclicos. | |
| US20110118462A1 (en) * | 2009-11-18 | 2011-05-19 | Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical Factory | N-heterocyclic substituent-containing antibiotic, preparation and use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4338438A (en) * | 1970-06-16 | 1982-07-06 | Merck & Co., Inc. | Cephalosporin antibiotics |
| DE2407715C2 (de) * | 1974-02-18 | 1982-12-02 | Bayer Ag, 5090 Leverkusen | Cephalosporine, Verfahren zu ihrer Herstellung sowie Arzneimittel |
| US4087424A (en) * | 1974-05-09 | 1978-05-02 | Toyama Chemical Co., Ltd. | Novel penicillins and cephalosporins and process for producing the same |
| US4219554A (en) * | 1974-05-09 | 1980-08-26 | Toyama Chemical Company, Limited | Novel penicillins and cephalosporins and process for producing same |
| US4112090A (en) * | 1974-05-09 | 1978-09-05 | Toyama Chemical Co., Ltd. | Novel penicillins and cephalosporins and process for producing the same |
| DE2720579A1 (de) * | 1977-05-07 | 1978-11-09 | Bayer Ag | Beta-lactam-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| EP0016900B1 (de) * | 1977-07-18 | 1983-11-16 | Ciba-Geigy Ag | Zwischenprodukte für die Herstellung von Cephalosporinderivaten, Verfahren zu ihrer Herstellung und Verwendung |
| US4313945A (en) * | 1978-11-23 | 1982-02-02 | Ciba-Geigy Corporation | 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping |
| EP0015240A1 (de) * | 1979-02-16 | 1980-09-03 | Ciba-Geigy Ag | Azacyclyl (thio) ureidoacetyl-Verbindungen und Verfahren zu ihrer Herstellung |
-
1980
- 1980-12-08 US US06/214,155 patent/US4464366A/en not_active Expired - Lifetime
- 1980-12-15 EP EP80810386A patent/EP0031794A3/de not_active Withdrawn
- 1980-12-17 ES ES497849A patent/ES497849A0/es active Granted
- 1980-12-18 NZ NZ195875A patent/NZ195875A/xx unknown
- 1980-12-18 IL IL61751A patent/IL61751A0/xx unknown
- 1980-12-18 DK DK540880A patent/DK540880A/da not_active Application Discontinuation
- 1980-12-18 ZA ZA00807914A patent/ZA807914B/xx unknown
- 1980-12-18 AU AU65518/80A patent/AU6551880A/en not_active Abandoned
- 1980-12-19 JP JP18182180A patent/JPS56103186A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0031794A3 (de) | 1982-02-03 |
| AU6551880A (en) | 1981-06-25 |
| IL61751A0 (en) | 1981-01-30 |
| EP0031794A2 (de) | 1981-07-08 |
| ZA807914B (en) | 1982-01-27 |
| JPS56103186A (en) | 1981-08-18 |
| ES497849A0 (es) | 1981-11-16 |
| US4464366A (en) | 1984-08-07 |
| NZ195875A (en) | 1983-04-12 |
| DK540880A (da) | 1981-06-20 |
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