ES8201155A1 - Un procedimiento para la preparacion de bases de 3-ami- no-5-(4-piridil)-1,2,4-triazol - Google Patents

Un procedimiento para la preparacion de bases de 3-ami- no-5-(4-piridil)-1,2,4-triazol

Info

Publication number
ES8201155A1
ES8201155A1 ES498821A ES498821A ES8201155A1 ES 8201155 A1 ES8201155 A1 ES 8201155A1 ES 498821 A ES498821 A ES 498821A ES 498821 A ES498821 A ES 498821A ES 8201155 A1 ES8201155 A1 ES 8201155A1
Authority
ES
Spain
Prior art keywords
pyridyl
amino
triazole
pyridylaminotriazole
therapeutic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498821A
Other languages
English (en)
Other versions
ES498821A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8201155A1 publication Critical patent/ES8201155A1/es
Publication of ES498821A0 publication Critical patent/ES498821A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86—Hydrazides; Thio or imino analogues thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE BASES DE 3-AMINO-5-(4-PIRIDIL)-1,2,4-TRIAZOL, DE FORMULA (I), DONDE R1 ES AMINO, N-MONO(ALQUIL INFERIOR) AMINO O N,N-DI(ALQUIL INTERIOR) AMINO; R2 ES AMINO, N-MONOALILAMINO, N-MONOMETILAMINO O N-METIL-N-BENCILAMINO; R3 ES HIDROGENO, ALQUILO INFERIOR, AMINO O N-MONO-(ALQUIL INFERIOR) AMINO, Y SUS SALES DE ADICION DE ACIDOS FARMACEUTICAMENTE ACEPTABLES.
ES498821A 1979-06-18 1981-01-26 Un procedimiento para la preparacion de bases de 3-ami- no-5-(4-piridil)-1,2,4-triazol Granted ES498821A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/049,737 US4276297A (en) 1979-06-18 1979-06-18 Pyridylaminotriazole therapeutic agents

Publications (2)

Publication Number Publication Date
ES8201155A1 true ES8201155A1 (es) 1981-12-01
ES498821A0 ES498821A0 (es) 1981-12-01

Family

ID=21961428

Family Applications (2)

Application Number Title Priority Date Filing Date
ES492522A Granted ES492522A0 (es) 1979-06-18 1980-06-17 Un procedimiento para la preparacion de bases de 3-amino-5-(4-piridil) 1,2,4-triazol.
ES498821A Granted ES498821A0 (es) 1979-06-18 1981-01-26 Un procedimiento para la preparacion de bases de 3-ami- no-5-(4-piridil)-1,2,4-triazol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES492522A Granted ES492522A0 (es) 1979-06-18 1980-06-17 Un procedimiento para la preparacion de bases de 3-amino-5-(4-piridil) 1,2,4-triazol.

Country Status (24)

Country Link
US (1) US4276297A (es)
JP (1) JPS565477A (es)
KR (2) KR840002173B1 (es)
AR (2) AR225766A1 (es)
AT (2) AT375655B (es)
BE (1) BE883859A (es)
CA (1) CA1140133A (es)
CH (1) CH644375A5 (es)
DE (1) DE3022302C2 (es)
DK (1) DK258180A (es)
ES (2) ES492522A0 (es)
FI (1) FI69842C (es)
FR (1) FR2459241A1 (es)
GB (1) GB2053910B (es)
GR (1) GR68731B (es)
IE (1) IE49913B1 (es)
IL (1) IL60332A (es)
IT (1) IT1140993B (es)
LU (1) LU82527A1 (es)
NL (1) NL182641C (es)
PH (1) PH16875A (es)
PT (1) PT71399A (es)
SE (1) SE441745B (es)
YU (2) YU41717B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR230994A1 (es) * 1981-08-31 1984-08-31 Pfizer Procedimiento para preparar compuesto de 3'-substituido-5'-(2-amino-4-piridil)-1',2',4'-triazol
JP2518515Y2 (ja) * 1993-09-22 1996-11-27 茂郎 槇島 水虫用医療包帯
PL415073A1 (pl) * 2014-12-19 2016-06-20 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1925654U (de) 1965-07-23 1965-10-21 Alfons Mann Zusatzeinrichtung fuer vergaser an benzinmotoren zur steigerung der motorenleistung.
CH521419A (de) * 1968-03-01 1972-04-15 Ciba Geigy Ag Verfahren zur Herstellung neuer Azofarbstoffe
GB1264798A (es) 1968-07-10 1972-02-23
US3647814A (en) * 1969-07-03 1972-03-07 Rohm & Haas Method for preparing 4-substituted-1 2 4-triazoles
NL7112373A (es) * 1970-09-25 1972-03-28
NL7112372A (es) * 1970-09-25 1972-03-28
GB1403866A (en) * 1971-12-06 1975-08-28 Wyeth John & Brother Ltd Derivatives of 3-amino-1,2,4-triazoles
US3879404A (en) * 1972-07-07 1975-04-22 John J Baldwin Certain 5-(pyridyl)-3(phenyl)-1,2,4-triazoles
US3873563A (en) * 1972-09-29 1975-03-25 Sakai Chemical Industry Co Method for manufacturing 4-amino-1,2,4-triazoles
US3928361A (en) * 1973-05-21 1975-12-23 Merck & Co Inc 1-(Sulfamoylphenylalkyl)-3,5-dipyridyl-1,2,4 triazoles
US3984558A (en) * 1973-05-21 1976-10-05 Merck & Co., Inc. 1,3,5-Trisubstituted-1,2,4-triazole compounds used as bronchodilators

Also Published As

Publication number Publication date
GR68731B (es) 1982-02-10
KR840002173B1 (ko) 1984-11-26
YU158780A (en) 1983-04-30
ES8105313A1 (es) 1981-06-01
IL60332A (en) 1983-09-30
ATA319280A (de) 1984-01-15
DK258180A (da) 1980-12-19
US4276297A (en) 1981-06-30
FI69842C (fi) 1986-05-26
YU41536B (en) 1987-08-31
BE883859A (fr) 1980-12-17
GB2053910A (en) 1981-02-11
SE8004498L (sv) 1980-12-19
AR225766A1 (es) 1982-04-30
ATA307583A (de) 1984-01-15
IE49913B1 (en) 1986-01-08
JPS565477A (en) 1981-01-20
KR830002756A (ko) 1983-05-30
KR840002172B1 (ko) 1984-11-26
AT375655B (de) 1984-08-27
CH644375A5 (fr) 1984-07-31
DE3022302C2 (de) 1984-03-01
SE441745B (sv) 1985-11-04
FI801929A7 (fi) 1980-12-19
CA1140133A (en) 1983-01-25
YU41717B (en) 1987-12-31
PH16875A (en) 1984-04-02
PT71399A (en) 1980-07-01
ES492522A0 (es) 1981-06-01
IL60332A0 (en) 1980-09-16
GB2053910B (en) 1983-04-20
FR2459241B1 (es) 1983-06-17
NL182641B (nl) 1987-11-16
FI69842B (fi) 1985-12-31
IT1140993B (it) 1986-10-10
NL8003496A (nl) 1980-12-22
DE3022302A1 (de) 1981-01-08
AT375656B (de) 1984-08-27
ES498821A0 (es) 1981-12-01
YU263382A (en) 1983-04-30
JPS617426B2 (es) 1986-03-06
NL182641C (nl) 1988-04-18
IT8022825A0 (it) 1980-06-17
LU82527A1 (fr) 1981-02-03
FR2459241A1 (fr) 1981-01-09
AR227436A1 (es) 1982-10-29
KR840004687A (ko) 1984-10-22
IE801250L (en) 1980-12-18

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