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Boots Co PLC
Original Assignee
Boots Co PLC
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Publication date
Application filed by Boots Co PLCfiledCriticalBoots Co PLC
Publication of ES8201975A1publicationCriticalpatent/ES8201975A1/es
Publication of ES497339A0publicationCriticalpatent/ES497339A0/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE QUINOLONA, DE FORMULA (I), EN LA QUE N VALE 0-2, R2 ES ALCOHILO C1-4 Y R1, R3, R4 Y R5 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE ALCOHILACION DE UN COMPUESTO DE QUINOLONA DE FORMULA (I), EN LA QUE N Y R2-R5 TIENEN EL MISMO SIGNIFICADO QUE SE HA INDICADO ANTERIORMENTE Y R1 ES HIDROGENO. LA REACCION DE ALCOHILACION SE LLEVA A CABO DE MODO CONVENCIONAL, EMPLEANDO AGENTES DE ALCOHILACION DE FORMULA R1-X, EN LA QUE X PUEDE SER CLORO, BROMO, SULFATO O ORTOFORMIATO, EN UN DISOLVENTE ORGANICO INERTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIHIPERTENSORA.
ES497339A1979-11-151980-12-01Procedimiento para preparar nuevos compuestos de quinolona
GrantedES497339A0
(es)