ES8205859A2 - Procedimiento para la obtencion de compuestos de acido 17-c-esteroide- -propionico - Google Patents

Procedimiento para la obtencion de compuestos de acido 17-c-esteroide- -propionico

Info

Publication number
ES8205859A2
ES8205859A2 ES489318A ES48931880A ES8205859A2 ES 8205859 A2 ES8205859 A2 ES 8205859A2 ES 489318 A ES489318 A ES 489318A ES 48931880 A ES48931880 A ES 48931880A ES 8205859 A2 ES8205859 A2 ES 8205859A2
Authority
ES
Spain
Prior art keywords
microorganism
preparation
mutants
steroid
side chains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES489318A
Other languages
English (en)
Other versions
ES489318A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Original Assignee
Henkel AG and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3519283&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8205859(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Henkel AG and Co KGaA filed Critical Henkel AG and Co KGaA
Publication of ES8205859A2 publication Critical patent/ES8205859A2/es
Publication of ES489318A0 publication Critical patent/ES489318A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/005—Degradation of the lateral chains at position 17

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDO 17-C-ESTEROTIDE-PROPIONICO, DE SUSTRATOS DE ESTEROIDES DE CADENAS LATERALES 17-C,MEDIANTE DEGRADACION SELECTIVA DE CADENAS LATERALES, EN CONDICIONES AEROBIAS Y DE INHIBIDORES DE LA DEGRADACION Y O DEL CRECIMIENTO DEL ANILLO. CONSISTE EN AISLAR Y CULTIVAR AEROBICAMENTE UNA CEPA SALVAJE DE MICROORGANISMOS CAPACITADA PARA EL CRECIMIENTO SOBRE COMPUESTOS DE ETERINA COMO UNICA FUENTE DE CARBONO; SOMETERLA A UN TRATAMIENTO SOBRE COMPUESTOS DE ESTERINA COMO UNICA FUENTES DE CARBONO; SOMETERLA A UNA TRATAMIENTO DE MUTACION POR METODOS CONVENCIONALES, CULTIVAR LA POPULACION DE MUTANTES QUE PROPORCIONAN LAS COMPUESTOS DE ACIDO 17-C Y AISLAR LAS CEPAS DE MUTANTES CON PRODUCCION OPTIMA DE DICHOS COMPUESTOS. ESTOS COMPUESTOS TIENE APLICACIONES PARA LA OBTENCION DE ESTEROIDES DE LA SERIE PROGESTERONA.
ES1980489318A 1979-03-07 1980-03-07 Procedimiento para la obtencion de compuestos de acido 17-c-esteroide- -propionico Granted ES489318A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0170979A AT386225B (de) 1979-03-07 1979-03-07 Verfahren zur hestellung von 17-c-steroid-alpha- propionsaeureverbindungen, insbesondere von 3-oxopregna-4-en-20-carbons|ure und/oder 3-oxo-pregna-1,4-dien-20-carbonsaeure

Publications (2)

Publication Number Publication Date
ES8205859A2 true ES8205859A2 (es) 1982-07-01
ES489318A0 ES489318A0 (es) 1982-07-01

Family

ID=3519283

Family Applications (1)

Application Number Title Priority Date Filing Date
ES1980489318A Granted ES489318A0 (es) 1979-03-07 1980-03-07 Procedimiento para la obtencion de compuestos de acido 17-c-esteroide- -propionico

Country Status (11)

Country Link
US (1) US4362815A (es)
EP (1) EP0015308B1 (es)
JP (2) JPS55127991A (es)
AT (1) AT386225B (es)
AU (1) AU538431B2 (es)
BR (1) BR8001330A (es)
CA (1) CA1141313A (es)
DE (1) DE2967658D1 (es)
DK (1) DK91680A (es)
ES (1) ES489318A0 (es)
NO (1) NO800647L (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3112981A1 (de) * 1981-04-01 1982-10-21 Henkel KGaA, 4000 Düsseldorf Verfahren zum gezielten mikrobiologischen abbau von gallensaeuren
AU581183B2 (en) * 1983-08-12 1989-02-16 Commonwealth Scientific And Industrial Research Organisation Process for the microbial preparation of steroid drug intermediates
NL8803141A (nl) * 1988-12-22 1990-07-16 Tno Werkwijze voor de microbiologische bereiding van steroiden; daarvoor bruikbare genetisch gemodificeerde micro-organismen.
CA2099526C (fr) * 1993-07-02 2005-06-21 Hydro-Quebec Additifs pour lubrifiants utilises dans le laminage de feuillards de lithium en films minces

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
US4032408A (en) * 1975-04-30 1977-06-28 G. D. Searle & Co. Process of preparing 3-oxo-pregna-4,17(20)-dien-21-carboxylic acid and esters with mycobacterium
US4029549A (en) * 1976-03-26 1977-06-14 The Upjohn Company Process of producing 9α-hydroxy-3-ketobisnorchol-4-en-22-oic with mycobacterium fortuitum
US4062729A (en) * 1976-11-26 1977-12-13 The Upjohn Company Microbial transformation of steroids
AT362086B (de) * 1978-04-17 1981-04-27 Henkel Kgaa Verfahren zur herstellung von 17-c-steroid- -alpha-propionsaeureverbindungen durch mikro- biellen seitenkettenabbau an 17-c-seitenketten- -steroidsubstraten

Also Published As

Publication number Publication date
AT386225B (de) 1988-07-25
US4362815A (en) 1982-12-07
JPH02119795A (ja) 1990-05-07
ATA170979A (de) 1987-12-15
EP0015308A1 (de) 1980-09-17
AU538431B2 (en) 1984-08-16
BR8001330A (pt) 1980-11-04
JPS55127991A (en) 1980-10-03
CA1141313A (en) 1983-02-15
DE2967658D1 (en) 1987-06-04
DK91680A (da) 1980-09-08
AU5613380A (en) 1980-09-11
EP0015308B1 (de) 1987-04-29
NO800647L (no) 1980-09-08
ES489318A0 (es) 1982-07-01

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