ES8300775A1 - "procedimiento para la fabricacion de un n-bencenosulfonil derivado de la cefamicina c". - Google Patents

"procedimiento para la fabricacion de un n-bencenosulfonil derivado de la cefamicina c".

Info

Publication number
ES8300775A1
ES8300775A1 ES508111A ES508111A ES8300775A1 ES 8300775 A1 ES8300775 A1 ES 8300775A1 ES 508111 A ES508111 A ES 508111A ES 508111 A ES508111 A ES 508111A ES 8300775 A1 ES8300775 A1 ES 8300775A1
Authority
ES
Spain
Prior art keywords
cephamycin
derivative
preparation
isolate
unsatisfactory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508111A
Other languages
English (en)
Other versions
ES508111A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Publication of ES8300775A1 publication Critical patent/ES8300775A1/es
Publication of ES508111A0 publication Critical patent/ES508111A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN N-BENCENOSULFONIL DERIVADO DE LA CEFAMINICINA C, DE FORMULA (I). CONSISTE EN LA REACCION DE LA CEFAMICINA C EN DISOLUCION ACUOSA CON CLORURO DE BENCENOSULFONILO. LA REACCION SE LLEVA A CABO EN UN MEDIO DE PH COMPRENDIDO ENTRE 8,0 Y 10,5. EL PRODUCTO OBTENIDO SE PRECIPITA A PARTIR DE LA DISOLUCION ACUOSA POR AJUSTE DEL PH ENTRE 1 Y 3 MEDIANTE UN ACIDO INORGANICO FUERTE. >ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS COMO ANTIBIOTICO.
ES508111A 1980-12-04 1981-12-04 "procedimiento para la fabricacion de un n-bencenosulfonil derivado de la cefamicina c". Granted ES508111A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55170274A JPS5795992A (en) 1980-12-04 1980-12-04 Novel derivative of cephamycin c and its preparation

Publications (2)

Publication Number Publication Date
ES8300775A1 true ES8300775A1 (es) 1982-11-01
ES508111A0 ES508111A0 (es) 1982-11-01

Family

ID=15901899

Family Applications (1)

Application Number Title Priority Date Filing Date
ES508111A Granted ES508111A0 (es) 1980-12-04 1981-12-04 "procedimiento para la fabricacion de un n-bencenosulfonil derivado de la cefamicina c".

Country Status (5)

Country Link
US (1) US4495348A (es)
EP (1) EP0053919B1 (es)
JP (1) JPS5795992A (es)
DE (1) DE3174355D1 (es)
ES (1) ES508111A0 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750199B2 (en) 2000-07-17 2004-06-15 Micrologix Biotech Inc. Antimicrobial sulfonamide derivatives of lipopeptide antibiotics
AU7893301A (en) * 2000-07-17 2002-01-30 Intrabiotics Pharmaceuticals Antimicrobial sulfonamide derivatives of lipopeptide antibiotics
US6737403B2 (en) 2000-07-17 2004-05-18 Micrologix Biotech Inc. Derivatives of laspartomycin and preparation and use thereof
US6511962B1 (en) 2000-07-17 2003-01-28 Micrologix Biotech Inc. Derivatives of laspartomycin and preparation and use thereof
CN103421024B (zh) * 2012-05-21 2016-08-03 上海医药工业研究院 制备头霉素c的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB143800A (en) * 1919-11-24 1920-06-03 Jules Delort Improvements in and relating to milk churns
CH541579A (de) * 1969-05-13 1973-09-15 Ciba Geigy Ag Verfahren zur Abtrennung von Cephalosporin C aus Rohlösungen
US4173702A (en) * 1969-08-12 1979-11-06 Eli Lilly And Company 7-(5-Amino-5-carboxyvaler-amido)-3-(carbamoyloxymethyl)-7-methoxy-3-cephem-4-carboxylic acid
US4302578A (en) * 1970-12-09 1981-11-24 Merck & Co., Inc. Cephalosporin antibiotics
JPS4950593A (es) * 1972-09-19 1974-05-16
GB1489231A (en) * 1974-02-20 1977-10-19 Alfa Farmaceutici Spa Process for the recovery of cephalosporin c and derivatives thereof
US4053286A (en) * 1974-09-23 1977-10-11 Merck & Co., Inc. Process for the preparation of cephalosporin antibiotics
US4283492A (en) * 1975-06-21 1981-08-11 Fujisawa Pharmaceutical Co., Ltd. Production of antibiotics WS-3442 A, B, C, D and E, and their acyl derivatives
JPS6052709B2 (ja) * 1977-12-28 1985-11-20 三共株式会社 セフアマイシン誘導体の製法
JPS54141794A (en) * 1978-04-04 1979-11-05 Nippon Kayaku Co Ltd Preparation of n-acylcephamycin c and its salt with organic base

Also Published As

Publication number Publication date
EP0053919A3 (en) 1983-01-26
US4495348A (en) 1985-01-22
EP0053919A2 (en) 1982-06-16
DE3174355D1 (en) 1986-05-15
JPS628118B2 (es) 1987-02-20
JPS5795992A (en) 1982-06-15
ES508111A0 (es) 1982-11-01
EP0053919B1 (en) 1986-04-09

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