ES8302711A1 - Proceso de produccion de un compuesto medicamentoso que con-tiene antibioticos de la serie ka-6643 - Google Patents

Proceso de produccion de un compuesto medicamentoso que con-tiene antibioticos de la serie ka-6643

Info

Publication number
ES8302711A1
ES8302711A1 ES506470A ES506470A ES8302711A1 ES 8302711 A1 ES8302711 A1 ES 8302711A1 ES 506470 A ES506470 A ES 506470A ES 506470 A ES506470 A ES 506470A ES 8302711 A1 ES8302711 A1 ES 8302711A1
Authority
ES
Spain
Prior art keywords
well
antibiotics
production process
compound containing
inoborgent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506470A
Other languages
English (en)
Other versions
ES506470A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55149177A external-priority patent/JPS5772982A/ja
Priority claimed from JP56031983A external-priority patent/JPS57145893A/ja
Priority claimed from JP56117449A external-priority patent/JPS5818384A/ja
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of ES506470A0 publication Critical patent/ES506470A0/es
Publication of ES8302711A1 publication Critical patent/ES8302711A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS QUE CONTIENEN ANTIBIOTICOS DE LA SERIE KA-6643, DE FORMULAS (I), (II), (III) O (IV), Y DE SUS SALES O ESTERES; COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIBACTERIANA E INHIBIDORA DE <021>-LACTAMASA. CONSISTE EN EL CULTIVO DE UNA CEPA PERTENECIENTE AL GENERO STREPTOMYCES, CAPAZ DE PRODUCIR UNA SUSTANCIA KA-6643, EN UN MEDIO DE CULTIVO LIQUIDO QUE CONTIENE FUENTES DE CARBONO Y NITROGENO ASIMILABLES, ASI COMO SALES INORGANICAS, EN CONDICIONES AEROBIAS, A TEMPERATURAS COMPRENDIDAS ENTRE 3<025>C Y 35<025>C; SEGUIDO DEL AISLAMIENTO DE LOS ANTIBIOTICOS DEL CALDO DE CULTIVO.
ES506470A 1980-10-24 1981-10-22 Proceso de produccion de un compuesto medicamentoso que con-tiene antibioticos de la serie ka-6643 Expired ES8302711A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP55149177A JPS5772982A (en) 1980-10-24 1980-10-24 Antibiotic substance and its preparation
JP56031983A JPS57145893A (en) 1981-03-06 1981-03-06 Antibiotic and its preparation
JP56117449A JPS5818384A (ja) 1981-07-27 1981-07-27 抗生物質およびその製造法

Publications (2)

Publication Number Publication Date
ES506470A0 ES506470A0 (es) 1983-02-01
ES8302711A1 true ES8302711A1 (es) 1983-02-01

Family

ID=27287538

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506470A Expired ES8302711A1 (es) 1980-10-24 1981-10-22 Proceso de produccion de un compuesto medicamentoso que con-tiene antibioticos de la serie ka-6643

Country Status (6)

Country Link
US (1) US4468350A (es)
EP (1) EP0050961B1 (es)
CA (1) CA1167400A (es)
DE (1) DE3170632D1 (es)
DK (1) DK469481A (es)
ES (1) ES8302711A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0074599A1 (en) * 1981-09-09 1983-03-23 Takeda Chemical Industries, Ltd. 5,6-cis-Carbapenem derivatives, their production and use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146610A (en) * 1974-03-28 1979-03-27 Beecham Group Limited Antibiotics mm13902
US4162304A (en) * 1975-03-15 1979-07-24 Beecham Group Limited Streptomycetal antibiotic
US4162324A (en) * 1975-11-21 1979-07-24 Merck & Co., Inc. Antibiotics 890A1 and 890A3
DE2862419D1 (en) * 1977-11-12 1984-07-26 Beecham Group Plc Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates
EP0005349A1 (en) * 1978-05-06 1979-11-14 Beecham Group Plc Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
AU534530B2 (en) * 1979-02-02 1984-02-02 Takeda Chemical Industries Ltd. 5-aza-(3.2.0)-heptane derivatives
JPS55136282A (en) * 1979-04-06 1980-10-23 Shionogi & Co Ltd Novel antibiotic pa-31088-4
JPS5683489A (en) * 1979-12-12 1981-07-08 Shionogi & Co Ltd New antibiotic pa-39504-x1 and it preparation
US4409147A (en) * 1980-03-10 1983-10-11 Takeda Chemical Industries, Ltd. Carbapenem compounds and their production

Also Published As

Publication number Publication date
ES506470A0 (es) 1983-02-01
DK469481A (da) 1982-04-25
EP0050961B1 (en) 1985-05-22
CA1167400A (en) 1984-05-15
US4468350A (en) 1984-08-28
DE3170632D1 (en) 1985-06-27
EP0050961A1 (en) 1982-05-05

Similar Documents

Publication Publication Date Title
ES457932A1 (es) Un procedimiento para la preparacion de nuevos compuestos antiparasitarios c-076, obtenidos en un caldo de fermenta- cion.
ES8302092A1 (es) Un procedimiento para la preparacion de nuevos derivados de los compuestos c-076.
ES8305418A1 (es) Un procedimiento para la preparacion de una nueva serie de macrolidas de la familia c-076-.
GB1491266A (en) Anti-tumor antibiotics aclacinomycins a and b
ES8103168A1 (es) Procedimiento para la produccion de etanol a partir de celu-losa
ES8203964A1 (es) Un procedimiento para la preparacion de compuestos de polie-ter antibioticos
DK294384A (da) Cl-1577 antibiotisk/antitumor virkende forbindelser samt fremgangsmaade til fremstilling deraf
ES485074A1 (es) Un metodo de produccion de la mezcla antibiotica a-21978
ES8308357A1 (es) Un procedimiento para la produccion de l-lisina.
KR900003206A (ko) 항생물질 머사시딘, 이의 제조방법 및 약제로서의 이의 용도
ES2068816T3 (es) Esteres y glicosidos de la castañoespermina.
ES8302091A1 (es) Un procedimiento para la produccion de compuestos de fermen-tacion hipocolesterolemicos.
ES478874A1 (es) Procedimiento de preparar 3-0(beta -d-glucuronopiranosil)- soja-sapogenol b.
ES8302085A1 (es) Procedimiento para la produccion de un nuevo antibiotico desiguado como sustancia mf 266.
ES380545A1 (es) Proceso de produccion de una nueva sustancia biologicamenteactiva, la pepstatina.
ES8105034A1 (es) Procedimiento para la produccion de una istamicina
GB1500965A (en) Cyclic ether antibiotics
JPS5540723A (en) Soil activator and its preparation
ES8304201A1 (es) Un procedimiento para la preparacion de nuevas lactonas macrociclicas.
ES8502161A1 (es) Un procedimiento para la produccion del antibiotico bbm-1644
ES475853A1 (es) Un procedimiento para la preparacion de los factores a, b, c, y d del antibiotico a-40104
ES8706835A1 (es) Un procedimiento para preparar compuestos de antraciclina
ATE1289T1 (de) Organische phosphor-verbindungen mit 3-hydroxyalkylphosphinsaeureestergruppen, deren herstellung und verwendung.
ES8404710A1 (es) Un procedimiento para la preparacion de un complejo antibiotico.
MD174C2 (ro) Hidroselenură de cobalt (II) dihidrată