ES8304064A1 - "un procedimiento para producir cloruro de acido de carnitina". - Google Patents

"un procedimiento para producir cloruro de acido de carnitina".

Info

Publication number
ES8304064A1
ES8304064A1 ES513658A ES513658A ES8304064A1 ES 8304064 A1 ES8304064 A1 ES 8304064A1 ES 513658 A ES513658 A ES 513658A ES 513658 A ES513658 A ES 513658A ES 8304064 A1 ES8304064 A1 ES 8304064A1
Authority
ES
Spain
Prior art keywords
carnitine
reaction
acid chloride
preparing
chlorining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513658A
Other languages
English (en)
Other versions
ES513658A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of ES8304064A1 publication Critical patent/ES8304064A1/es
Publication of ES513658A0 publication Critical patent/ES513658A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/115—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR CLORURO DE ACIDO DE CARNITINA. SE CLORA CARNITINA POR REACCION DE ESTA CON UN AGENTE CLORANTE ELEGIDO DE ENTRE CLORURO DE TIONILO, ETER DICLOROMETILICO Y CLORURO DE OXALILO, A LA TEMPERATURA AMBIENTE, SIENDO EL TIEMPO DE ESTANCIA EN REACCION EL COMPRENDIDO ENTRE 1 HORA Y 12 HORAS. LA REACCION SE DEBE LLEVAR A CABO MANTENIENDO UNA RELACION MOLAR CARNITINA/AGENTE CLORANTE COMPRENDIDA ENTRE 1:1 Y 1:3. SE UTILIZA COMO INTERMEDIARIO PARA LA PREPARACION DE DERIVADOS DE CARNITINA, TAL COMO ESTERES Y AMIDAS.
ES513658A 1981-07-03 1982-07-02 "un procedimiento para producir cloruro de acido de carnitina". Granted ES513658A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48817/81A IT1171360B (it) 1981-07-03 1981-07-03 Procedimento per la preparazione del cloruro acido di carnitina

Publications (2)

Publication Number Publication Date
ES8304064A1 true ES8304064A1 (es) 1983-03-01
ES513658A0 ES513658A0 (es) 1983-03-01

Family

ID=11268676

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513658A Granted ES513658A0 (es) 1981-07-03 1982-07-02 "un procedimiento para producir cloruro de acido de carnitina".

Country Status (18)

Country Link
JP (1) JPS5815943A (es)
KR (1) KR860001886B1 (es)
AT (1) AT390057B (es)
BE (1) BE893713A (es)
CA (1) CA1186332A (es)
CH (1) CH648546A5 (es)
DE (1) DE3224666A1 (es)
DK (1) DK154425C (es)
ES (1) ES513658A0 (es)
FR (1) FR2510559B1 (es)
GB (1) GB2101133B (es)
GR (1) GR76546B (es)
IE (1) IE53279B1 (es)
IL (1) IL66251A0 (es)
IT (1) IT1171360B (es)
LU (1) LU84244A1 (es)
NL (1) NL189666C (es)
SE (1) SE448724B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190358B (it) * 1985-05-24 1988-02-16 Sclavo Spa Procedimento per la preparazione di l-carnitina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3940439A (en) * 1973-11-14 1976-02-24 G. D. Searle & Co. Acid chloride synthesis
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
DE2943433A1 (de) * 1979-10-26 1981-05-07 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von carbonsaeurehalogeniden

Also Published As

Publication number Publication date
ATA257382A (de) 1989-08-15
DK154425B (da) 1988-11-14
KR840000475A (ko) 1984-02-22
CA1186332A (en) 1985-04-30
DE3224666C2 (es) 1991-01-24
IT8148817A1 (it) 1983-01-03
AT390057B (de) 1990-03-12
NL189666C (nl) 1993-06-16
GB2101133B (en) 1985-08-14
NL8202677A (nl) 1983-02-01
NL189666B (nl) 1993-01-18
LU84244A1 (fr) 1983-01-20
ES513658A0 (es) 1983-03-01
DK154425C (da) 1989-04-10
DE3224666A1 (de) 1983-01-20
KR860001886B1 (ko) 1986-10-24
IT1171360B (it) 1987-06-10
IL66251A0 (en) 1982-11-30
SE8204117L (sv) 1983-01-04
JPS5815943A (ja) 1983-01-29
BE893713A (fr) 1982-10-18
FR2510559A1 (fr) 1983-02-04
FR2510559B1 (fr) 1986-05-09
IE821524L (en) 1983-01-03
GR76546B (es) 1984-08-10
SE448724B (sv) 1987-03-16
DK295482A (da) 1983-01-04
CH648546A5 (it) 1985-03-29
JPH0244300B2 (es) 1990-10-03
GB2101133A (en) 1983-01-12
IE53279B1 (en) 1988-09-28
SE8204117D0 (sv) 1982-07-02
IT8148817A0 (it) 1981-07-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303