ES8304534A1 - "procedimiento de preparacion de derivados de 1-fenil-1-hidroxi-etilamina". - Google Patents

"procedimiento de preparacion de derivados de 1-fenil-1-hidroxi-etilamina".

Info

Publication number
ES8304534A1
ES8304534A1 ES513109A ES513109A ES8304534A1 ES 8304534 A1 ES8304534 A1 ES 8304534A1 ES 513109 A ES513109 A ES 513109A ES 513109 A ES513109 A ES 513109A ES 8304534 A1 ES8304534 A1 ES 8304534A1
Authority
ES
Spain
Prior art keywords
group
image
carbon atoms
preparation
groups containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513109A
Other languages
English (en)
Other versions
ES513109A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Draco AB
Original Assignee
Draco AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco AB filed Critical Draco AB
Publication of ES8304534A1 publication Critical patent/ES8304534A1/es
Publication of ES513109A0 publication Critical patent/ES513109A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Luminescent Compositions (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 1-FENIL-1-HIDROXI-ETILAMINA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R, R Y R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE REDUCCION DE UN COMPUESTO DE FORMULA (II), EN LA QUE R, R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REDUCCION SE LLEVA A CABO SIGUIENDO METODOS CONVENCIONALES, TALES COMO HIDROGENACION CATALITICA, O CON HIDRUROS TALES COMO BOROHIDRURO SODICO. EL COMPUESTO OBTENIDO SE PUEDE RESOLVER EN SUS ANTIPODAS OPTICOS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES PULMONARES.
ES513109A 1980-07-09 1982-06-15 "procedimiento de preparacion de derivados de 1-fenil-1-hidroxi-etilamina". Granted ES513109A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8022439 1980-07-09
GB8116441 1981-05-29

Publications (2)

Publication Number Publication Date
ES8304534A1 true ES8304534A1 (es) 1983-03-01
ES513109A0 ES513109A0 (es) 1983-03-01

Family

ID=26276161

Family Applications (3)

Application Number Title Priority Date Filing Date
ES503768A Expired ES8300678A1 (es) 1980-07-09 1981-07-08 Procedimiento de preparacion de derivados de 1-fenil-1-hi- droxi-etilamina
ES513108A Expired ES8304072A1 (es) 1980-07-09 1982-06-15 "procedimiento de preparacion de derivados de 1-fenil-1-hidroxi-etilamina".
ES513109A Granted ES513109A0 (es) 1980-07-09 1982-06-15 "procedimiento de preparacion de derivados de 1-fenil-1-hidroxi-etilamina".

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES503768A Expired ES8300678A1 (es) 1980-07-09 1981-07-08 Procedimiento de preparacion de derivados de 1-fenil-1-hi- droxi-etilamina
ES513108A Expired ES8304072A1 (es) 1980-07-09 1982-06-15 "procedimiento de preparacion de derivados de 1-fenil-1-hidroxi-etilamina".

Country Status (29)

Country Link
US (2) US4419364A (es)
EP (1) EP0043807B1 (es)
KR (3) KR850000301B1 (es)
AT (1) ATE7689T1 (es)
AU (1) AU539976B2 (es)
CA (1) CA1180021A (es)
CS (1) CS221845B2 (es)
CY (1) CY1273A (es)
DD (1) DD202001A5 (es)
DE (1) DE3163871D1 (es)
DK (1) DK157678C (es)
ES (3) ES8300678A1 (es)
FI (1) FI73666C (es)
GR (1) GR74291B (es)
HK (1) HK5385A (es)
HU (2) HU184959B (es)
IE (1) IE51373B1 (es)
IS (1) IS1262B6 (es)
LU (1) LU88304I2 (es)
MX (1) MX9203239A (es)
MY (1) MY8700026A (es)
NO (2) NO152130C (es)
NZ (1) NZ197628A (es)
PH (2) PH16535A (es)
PL (1) PL128513B1 (es)
PT (1) PT73336B (es)
SG (1) SG79784G (es)
SU (1) SU1128830A3 (es)
YU (3) YU42116B (es)

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SE9000948D0 (sv) * 1990-03-16 1990-03-16 Draco Ab New use
US5830422A (en) * 1995-06-23 1998-11-03 Ormiston Mining And Smelting Co. Ltd. Method for production of sodium bicarbonate, sodium carbonate and ammonium sulfate from sodium sulfate
EP0892639A4 (en) * 1996-01-29 1999-06-09 Savor Evelyn PROCESS FOR THE TREATMENT OF UNWANTED UTERINE CONTRACTIONS USING OPTICALLY PURE R OR RR ISOMERS OF AGONIST -g (b) -2 ADRENERGIC AGONISTS
SE9604752D0 (sv) * 1996-12-20 1996-12-20 Astra Ab Formulation and use
KR20030085658A (ko) * 2002-04-30 2003-11-07 한올제약주식회사 밤부테롤의 개선된 합성방법
EP1542672B1 (en) * 2002-08-08 2008-09-03 Wen Tan R-bambuterol, its preparation and therapeutic uses
US7495028B2 (en) * 2002-08-08 2009-02-24 Wen Tan R-bambuterol, its preparation and therapeutic uses
RU2387646C2 (ru) * 2003-08-29 2010-04-27 Рэнбакси Лабораториз Лимитед Ингибиторы фосфодиэстеразы типа-iv
US20070259874A1 (en) * 2003-11-26 2007-11-08 Palle Venkata P Phosphodiesterase Inhibitors
WO2006081986A1 (en) * 2005-02-07 2006-08-10 F.Hoffmann-La Roche Ag Bambuterol and integrin inhibitor combination
WO2007031838A1 (en) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
WO2007045979A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
AU2006305620A1 (en) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
JO2868B1 (en) 2006-08-22 2015-03-15 رانبكسي لابوراتوريز ليمتد Inhibitors of metabolic protein protein enzyme
WO2008035316A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
EA200900472A1 (ru) * 2006-09-22 2009-10-30 Ранбакси Лабораторис Лимитед Ингибиторы фосфодиэстеразы iv типа
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
US20110130403A1 (en) * 2007-03-14 2011-06-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
SI2124944T1 (sl) * 2007-03-14 2012-05-31 Ranbaxy Lab Ltd Derivati pirazolo b piridina kot inhibitorji fosfodiesteraze
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
CN103119030A (zh) 2010-07-30 2013-05-22 兰贝克赛实验室有限公司 基质金属蛋白酶抑制剂
US20140148459A1 (en) 2010-09-24 2014-05-29 Ranbaxy Laboratories Limited Matrix metalloproteinase inhibitors
MY176727A (en) 2012-12-03 2020-08-20 Pfizer Selective androgen receptor modulators
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
CN104557614B (zh) * 2014-12-15 2017-01-04 广东东阳光药业有限公司 一种胺的还原方法
CN105622461B (zh) * 2016-01-29 2018-06-19 华南理工大学 一种化合物及其制备方法与应用
CN105859589B (zh) * 2016-04-05 2018-09-28 深圳市康立生生物科技有限公司 一种制备班布特罗杂质c的方法
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
CN109942462B (zh) * 2019-03-06 2022-01-14 宏冠生物药业有限公司 一种盐酸班布特罗的合成工艺
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
CN117069620A (zh) * 2022-05-17 2023-11-17 成都施贝康生物医药科技有限公司 一种间苯三酚衍生物及其制备和用途
CN120583945A (zh) 2023-01-20 2025-09-02 阿托基公司 用于治疗或预防肌肉消耗的β2-肾上腺素能受体激动剂
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses
CN117586152B (zh) * 2023-11-23 2026-04-03 黑龙江乌苏里江制药有限公司 一种盐酸班布特罗的制备方法
GB202403169D0 (en) 2024-03-05 2024-04-17 Atrogi Ab New medical uses
WO2025238248A1 (en) 2024-05-17 2025-11-20 Atrogi Ab USE OF β2-ADRENERGIC RECEPTOR AGONISTS IN TREATING MUSCLE WASTING
CN120585720A (zh) * 2025-06-12 2025-09-05 肇庆学院 一种双靶点药物的经鼻给药制剂及其应用

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DK85789C (da) 1955-07-05 1958-06-30 Cilag Ag Fremgangsmåde til fremstilling af d,1- eller 1-isopropyl-aminometyl-(3,4-dihydroksy-fenyl)-karbinol eller salte deraf.
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Also Published As

Publication number Publication date
CA1180021A (en) 1984-12-27
LU88304I2 (fr) 1994-05-04
YU43168B (en) 1989-04-30
GR74291B (es) 1984-06-21
IE811522L (en) 1982-01-09
CS221845B2 (en) 1983-04-29
AU539976B2 (en) 1984-10-25
YU86483A (en) 1983-12-31
HU184959B (en) 1984-11-28
KR850002741A (ko) 1985-05-15
DK303481A (da) 1982-01-10
KR850002740A (ko) 1985-05-15
SU1128830A3 (ru) 1984-12-07
PH16535A (en) 1983-11-10
FI812158L (fi) 1982-01-10
FI73666B (fi) 1987-07-31
YU42116B (en) 1988-04-30
US4451663A (en) 1984-05-29
ES513108A0 (es) 1983-02-16
IE51373B1 (en) 1986-12-10
ES503768A0 (es) 1982-11-01
EP0043807B1 (en) 1984-05-30
DK157678B (da) 1990-02-05
FI73666C (fi) 1987-11-09
CY1273A (en) 1985-03-08
NZ197628A (en) 1985-07-12
YU170481A (en) 1983-12-31
SG79784G (en) 1985-04-26
NO152130B (no) 1985-04-29
HU187611B (en) 1986-02-28
US4419364A (en) 1983-12-06
KR850000301B1 (ko) 1985-03-18
KR850000870B1 (ko) 1985-06-22
HK5385A (en) 1985-01-25
PT73336A (en) 1981-08-01
YU43169B (en) 1989-04-30
DK157678C (da) 1990-06-18
IS1262B6 (is) 1987-03-27
PH19447A (en) 1986-04-18
PT73336B (en) 1983-09-01
IS2657A7 (is) 1982-01-10
NO1996008I1 (no) 1996-06-27
EP0043807A2 (en) 1982-01-13
AU7261881A (en) 1982-01-14
NO812311L (no) 1982-01-11
PL232108A1 (es) 1982-08-02
EP0043807A3 (en) 1982-09-22
ES8300678A1 (es) 1982-11-01
PL128513B1 (en) 1984-02-29
MX9203239A (es) 1992-07-01
KR830006174A (ko) 1983-09-20
ATE7689T1 (de) 1984-06-15
MY8700026A (en) 1987-12-31
ES513109A0 (es) 1983-03-01
DE3163871D1 (en) 1984-07-05
NO152130C (no) 1985-08-07
YU86383A (en) 1983-12-31
DD202001A5 (de) 1983-08-24
KR850000871B1 (ko) 1985-06-22
ES8304072A1 (es) 1983-02-16

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