ES8304923A1 - Un procedimiento para la preparacion de un peptido. - Google Patents
Un procedimiento para la preparacion de un peptido.Info
- Publication number
- ES8304923A1 ES8304923A1 ES508467A ES508467A ES8304923A1 ES 8304923 A1 ES8304923 A1 ES 8304923A1 ES 508467 A ES508467 A ES 508467A ES 508467 A ES508467 A ES 508467A ES 8304923 A1 ES8304923 A1 ES 8304923A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- carboxy
- peptide
- procedure
- certain substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PEPTIDOS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R , R , R , R Y R PUDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), O UNA SAL DEL MISMO, CON UN COMPUESTO DE FORMULA (III) O UNA SAL DEL MISMO, EN LAS QUE R<A ES ALCANOILO O ARALCANOILO; R<A ES CARBOXI PROTEGIDO; R<A ES GRUPO PROTECTOR DE AMINO; Y R 3 Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); SEGUIDA DE LA REACCION DE ELIMINACION DE LOS GRUPOS PROTECTORES. LA REACCION DE FORMACION DEL ENLACE PEPTIDICO SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN AGENTE DE CONDENSACION, EN CONDICIONES ANHIDRAS, A UNA TEMPERATURA -20 C Y LA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTITUMORAL Y COMO INTERMEDIOS PARA LA SINTESIS DE OTROS COMPUESTOS CON ACTIVIDAD BIOLOGICA.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8041627 | 1980-12-31 | ||
| GB8111797 | 1981-04-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES508467A0 ES508467A0 (es) | 1983-03-16 |
| ES8304923A1 true ES8304923A1 (es) | 1983-03-16 |
Family
ID=26278010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES508467A Expired ES8304923A1 (es) | 1980-12-31 | 1981-12-30 | Un procedimiento para la preparacion de un peptido. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4493794A (es) |
| EP (1) | EP0055846B1 (es) |
| JP (1) | JPH068268B2 (es) |
| AU (1) | AU7913481A (es) |
| CA (1) | CA1247084A (es) |
| DE (1) | DE3174158D1 (es) |
| DK (1) | DK577281A (es) |
| ES (1) | ES8304923A1 (es) |
| GR (1) | GR75126B (es) |
| HU (1) | HU188120B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4565653A (en) * | 1984-03-30 | 1986-01-21 | Pfizer Inc. | Acyltripeptide immunostimulants |
| EP0428849A3 (en) * | 1989-09-28 | 1991-07-31 | Hoechst Aktiengesellschaft | Retroviral protease inhibitors |
| GB9022301D0 (en) * | 1990-10-15 | 1990-11-28 | Myson Group Plc | Heater assembly |
| ZA976421B (en) * | 1996-07-22 | 1998-01-22 | Boehringer Mannheim Italia | New bis-platinum complexes with polyamine ligands as antitumor agents. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1431724A (en) * | 1973-01-08 | 1976-04-14 | Tektronix Inc | System for acquiring processing and displaying information |
| GB2033906B (en) * | 1978-10-19 | 1982-12-01 | Anvar | Water-soluble compounds derived from extracts of streptomyces stimulosus process for their production and compositions containing them |
| FR2442889A1 (fr) * | 1978-10-19 | 1980-06-27 | Anvar | Nouveaux composes hydrosolubles provenant d'extraits de streptomyces stimulosus, leur obtention, leur application a titre d'adjuvants immunologiques et compositions les contenant |
| US4311640A (en) * | 1978-11-14 | 1982-01-19 | Fujisawa Pharmaceutical Co., Ltd. | Peptide, process for preparation thereof and use thereof |
| JPS5585552A (en) * | 1978-11-14 | 1980-06-27 | Fujisawa Pharmaceut Co Ltd | New lactyltetrapeptide |
| US4231910A (en) * | 1979-02-08 | 1980-11-04 | Dow Corning Corporation | Primer composition |
| FR2460290A1 (fr) * | 1979-06-29 | 1981-01-23 | Rhone Poulenc Ind | Nouveaux tetra- ou pentapeptides, leur preparation et les medicaments qui les contiennent |
| JPH0295412A (ja) * | 1988-09-30 | 1990-04-06 | Toyobo Co Ltd | 中空糸膜型気体分離膜装置 |
-
1981
- 1981-12-09 US US06/328,997 patent/US4493794A/en not_active Expired - Fee Related
- 1981-12-11 GR GR66776A patent/GR75126B/el unknown
- 1981-12-23 EP EP81110709A patent/EP0055846B1/en not_active Expired
- 1981-12-23 DK DK577281A patent/DK577281A/da not_active Application Discontinuation
- 1981-12-23 DE DE8181110709T patent/DE3174158D1/de not_active Expired
- 1981-12-25 JP JP57000142A patent/JPH068268B2/ja not_active Expired - Lifetime
- 1981-12-30 CA CA000393385A patent/CA1247084A/en not_active Expired
- 1981-12-30 ES ES508467A patent/ES8304923A1/es not_active Expired
- 1981-12-30 HU HU814032A patent/HU188120B/hu unknown
- 1981-12-31 AU AU79134/81A patent/AU7913481A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0055846A1 (en) | 1982-07-14 |
| US4493794A (en) | 1985-01-15 |
| ES508467A0 (es) | 1983-03-16 |
| CA1247084A (en) | 1988-12-20 |
| HU188120B (en) | 1986-03-28 |
| JPS57136555A (en) | 1982-08-23 |
| DE3174158D1 (en) | 1986-04-24 |
| JPH068268B2 (ja) | 1994-02-02 |
| AU7913481A (en) | 1982-07-08 |
| EP0055846B1 (en) | 1986-03-19 |
| GR75126B (es) | 1984-07-13 |
| DK577281A (da) | 1982-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990405 |