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Universitat Autonoma de Barcelona UAB
Original Assignee
Universitat Autonoma de Barcelona UAB
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Filing date
Publication date
Application filed by Universitat Autonoma de Barcelona UABfiledCriticalUniversitat Autonoma de Barcelona UAB
Priority to ES513679ApriorityCriticalpatent/ES8304960A1/es
Publication of ES513679A0publicationCriticalpatent/ES513679A0/es
Publication of ES8304960A1publicationCriticalpatent/ES8304960A1/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE (S)-5-R-METIL-(5H)FURAN-2-ONAS, DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE 5-DESOXI-5-R-~F-D-RIBONOLACTONAS CON UN EQUIVALENTE DE ORTOFORMIATO DE ETILO, EN EL SENO DE TETRAHIDROFURANO, A LA TEMPERATURA DE REFLUJO DE LA MEZCLA DE REACCION; SEGUIDA DE LA PIROLISIS DE LA 5-DESOXI-5-R-2,3-O-ETOXIMETILEN-~F-D-RIBONOLACTONA FORMADA, POR CALENTAMIENTO A LA TEMPERATURA DE 220 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD CARDIOTONICA, ANTINEOPLASTICA, FUNGICIDA, ETC.
ES513679A1982-07-021982-07-02"procedimiento para la obtencion de (s)-5-r-metil-(5h)furan-2-onas".
ExpiredES8304960A1
(es)