ES8403442A1 - Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas. - Google Patents
Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas.Info
- Publication number
- ES8403442A1 ES8403442A1 ES519440A ES519440A ES8403442A1 ES 8403442 A1 ES8403442 A1 ES 8403442A1 ES 519440 A ES519440 A ES 519440A ES 519440 A ES519440 A ES 519440A ES 8403442 A1 ES8403442 A1 ES 8403442A1
- Authority
- ES
- Spain
- Prior art keywords
- cyclohexenes
- cyclohexanols
- arylmethyl
- cyclohexanes
- medicaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000005002 aryl methyl group Chemical group 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DXDBGSMRYVGPJM-UHFFFAOYSA-N azinous acid Chemical compound ON.ON DXDBGSMRYVGPJM-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE 1-2-(ARILMETIL)ARIL-4-OXOCICLOHEXANOL-OXIMAS, DE FORMULA GENERAL (I), EN LA QUE X E Y SON CADA UNO DE ELLOS, INDEPENDIENTEMENTE, HIDROGENO, ALOGENO, ALCOXI DE 1 A 2 ATOMOS DE CARBONO O ALCOHILO INFERIOR.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), EN LA QUE X E Y TIENEN EL SIGNIFICADO YA INDICADO, CON CLOROHIDRATO DE HIDROXILAMINA.DE APLICACION EN LA PREPARACION DE COMPOSICIONES FARMACEUTICAS UTILIZADAS COMO ANTIDEPRESIVOS Y ANTICONVULSIVOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/258,097 US4313959A (en) | 1981-04-27 | 1981-04-27 | (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8403442A1 true ES8403442A1 (es) | 1984-03-16 |
| ES519440A0 ES519440A0 (es) | 1984-03-16 |
Family
ID=22979083
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES511559A Granted ES511559A0 (es) | 1981-04-27 | 1982-04-21 | "un procedimiento para la preparacion de (arimeltil) fenil-aminociclohexanos y -ciclohexenos". |
| ES519440A Granted ES519440A0 (es) | 1981-04-27 | 1983-02-01 | Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES511559A Granted ES511559A0 (es) | 1981-04-27 | 1982-04-21 | "un procedimiento para la preparacion de (arimeltil) fenil-aminociclohexanos y -ciclohexenos". |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4313959A (es) |
| EP (1) | EP0063793A3 (es) |
| JP (1) | JPS57183747A (es) |
| ES (2) | ES511559A0 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4391827A (en) * | 1980-09-08 | 1983-07-05 | Pfizer Inc. | 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor |
| US5239110A (en) * | 1992-12-30 | 1993-08-24 | Sterling Winthrop, Inc. | Phenylcyclohexanol derivatives as agents for treating CNS disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3652769A (en) * | 1969-10-01 | 1972-03-28 | Merck & Co Inc | Cycloalkylamines in the treatment of mental disorders involving depression and compositions therefor |
| GB1327691A (en) * | 1970-08-31 | 1973-08-22 | Upjohn Co | Phenyl cyclohexenylamines and the preparation thereof |
| GB1443441A (en) * | 1973-02-24 | 1976-07-21 | Beecham Group Ltd | Pharmaceutical compositions comprising diphenylpropanolamine deri vatives |
| US4263317A (en) * | 1979-09-06 | 1981-04-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s |
-
1981
- 1981-04-27 US US06/258,097 patent/US4313959A/en not_active Expired - Fee Related
-
1982
- 1982-04-21 ES ES511559A patent/ES511559A0/es active Granted
- 1982-04-22 EP EP82103403A patent/EP0063793A3/en not_active Withdrawn
- 1982-04-26 JP JP57068887A patent/JPS57183747A/ja active Pending
-
1983
- 1983-02-01 ES ES519440A patent/ES519440A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8306705A1 (es) | 1983-06-01 |
| EP0063793A2 (en) | 1982-11-03 |
| ES519440A0 (es) | 1984-03-16 |
| ES511559A0 (es) | 1983-06-01 |
| US4313959A (en) | 1982-02-02 |
| EP0063793A3 (en) | 1983-01-19 |
| JPS57183747A (en) | 1982-11-12 |
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