ES8305210A1 - Procedimiento de preparacion de eteres de fenoles. - Google Patents
Procedimiento de preparacion de eteres de fenoles.Info
- Publication number
- ES8305210A1 ES8305210A1 ES512830A ES512830A ES8305210A1 ES 8305210 A1 ES8305210 A1 ES 8305210A1 ES 512830 A ES512830 A ES 512830A ES 512830 A ES512830 A ES 512830A ES 8305210 A1 ES8305210 A1 ES 8305210A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- phenol ethers
- medicines
- preparation
- cardiovascular system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ETERES DE FENOLES Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R -R PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 3 O 4. CONSISTE EN LA REACCION DE UNA CETONA DE FORMULA (II), EN LA QUE R Y N TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON LA HEPICLORHIDRINA, EN PRESENCIA DE UN AGENTE ALCALINO, EN UN DISOLVENTE ACUOSO U ORGANICO; SEGUIDA DE LA REACCION DEL PRODUCTO OBTENIDO CON UNA AMINA DE FORMULA R NHR , EN LA QUE R Y R SON LOS MISMOS QUE EN LA FORMULA (I); Y, FINALMENTE, REDUCCION CON BOROHIDRURO DE SODIO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD SOBRE EL SISTEMA CARDIVASCULAR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8111242A FR2507181A1 (fr) | 1981-06-05 | 1981-06-05 | Nouveaux ethers de phenol actifs sur le systeme cardiovasculaire, leur procede de preparation et leur utilisation dans des medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8305210A1 true ES8305210A1 (es) | 1983-04-01 |
| ES512830A0 ES512830A0 (es) | 1983-04-01 |
Family
ID=9259266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES512830A Granted ES512830A0 (es) | 1981-06-05 | 1982-06-03 | Procedimiento de preparacion de eteres de fenoles. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4435426A (es) |
| EP (1) | EP0067106B1 (es) |
| JP (1) | JPS5849344A (es) |
| KR (1) | KR840000473A (es) |
| AR (1) | AR230425A1 (es) |
| AT (1) | ATE12631T1 (es) |
| AU (1) | AU8410082A (es) |
| CA (1) | CA1190942A (es) |
| CS (1) | CS228933B2 (es) |
| DD (1) | DD207707A5 (es) |
| DE (1) | DE3262965D1 (es) |
| DK (1) | DK252482A (es) |
| ES (1) | ES512830A0 (es) |
| FI (1) | FI821964A7 (es) |
| FR (1) | FR2507181A1 (es) |
| GR (1) | GR79490B (es) |
| HU (1) | HU186522B (es) |
| IE (1) | IE53276B1 (es) |
| IL (1) | IL65866A (es) |
| NO (1) | NO153053C (es) |
| NZ (1) | NZ200858A (es) |
| PT (1) | PT75018B (es) |
| SU (1) | SU1114333A3 (es) |
| YU (1) | YU120282A (es) |
| ZA (1) | ZA823856B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101522597B (zh) | 2006-10-03 | 2013-05-29 | 墨西哥化学阿玛科股份有限公司 | 通过脱卤化氢制备c3-c6(氢)氟烯烃的方法 |
| US20170275662A1 (en) | 2016-03-22 | 2017-09-28 | The Quaker Oats Company | Method and Apparatus for Controlled Hydrolysis |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1023214A (en) | 1962-12-17 | 1966-03-23 | Ici Ltd | Carbocyclic hydroxyamines |
| GB1069343A (en) | 1963-09-10 | 1967-05-17 | Ici Ltd | Propanolamine derivatives |
| ES330705A1 (es) | 1965-09-01 | 1967-10-01 | Boehringer Sohn Ingelheim | Procedimiento para la preparacion de nuevos ariloxi-2-hidroxi-3-aminopropanos sustituidos |
| US3641152A (en) * | 1968-09-23 | 1972-02-08 | Warner Lambert Pharmaceutical | 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines |
| ZA705118B (en) | 1969-07-30 | 1971-09-29 | Erba Carlo Spa | New basic compounds and process for their preparation |
| DE2130393C3 (de) | 1970-06-22 | 1981-02-26 | E.R. Squibb & Sons Inc., New York, N.Y. (V.St.A.) | 6,7-Dihydroxy -5,6,7,8-tetrahydronaphthyloxyaminopropanole und ihre Salze mit Säuren sowie ihre Verwendung bei der Bekämpfung von Herzerkrankungen |
| US3829498A (en) | 1971-05-25 | 1974-08-13 | Warner Lambert Co | Process for preparing 5-hydroxy-1-tetralone |
| GB1442421A (en) * | 1972-07-03 | 1976-07-14 | Squibb & Sons Inc | Propanolamines |
| GB1493848A (en) | 1975-07-24 | 1977-11-30 | Beecham Group Ltd | Aryltetralins |
| US4048231A (en) | 1976-02-09 | 1977-09-13 | E. R. Squibb & Sons, Inc. | 4-[3-(Substituted amino)-2-hydroxypropoxy]-5,6,7,8-tetrahydro-1,6,7-naphthalenetriols |
| DE2810869A1 (de) * | 1977-03-24 | 1978-09-28 | Sandoz Ag | 3-amino-2-hydroxypropoxy-derivate, ihre herstellung und verwendung |
| DE2962112D1 (en) | 1978-02-08 | 1982-03-25 | Ici Plc | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them |
| GB2065647A (en) | 1979-12-14 | 1981-07-01 | Ciba Geigy Ag | Cyclopropanecarboxylic acid alkynyl esters processes for producing them and their use as pesticides |
-
1981
- 1981-06-05 FR FR8111242A patent/FR2507181A1/fr active Granted
-
1982
- 1982-05-21 IE IE1226/82A patent/IE53276B1/en unknown
- 1982-05-24 AU AU84100/82A patent/AU8410082A/en not_active Abandoned
- 1982-05-24 IL IL65866A patent/IL65866A/xx unknown
- 1982-05-25 US US06/381,796 patent/US4435426A/en not_active Expired - Lifetime
- 1982-05-25 GR GR68248A patent/GR79490B/el unknown
- 1982-06-01 EP EP82400998A patent/EP0067106B1/fr not_active Expired
- 1982-06-01 JP JP57092256A patent/JPS5849344A/ja active Pending
- 1982-06-01 DE DE8282400998T patent/DE3262965D1/de not_active Expired
- 1982-06-01 AT AT82400998T patent/ATE12631T1/de not_active IP Right Cessation
- 1982-06-02 FI FI821964A patent/FI821964A7/fi not_active Application Discontinuation
- 1982-06-02 CS CS824089A patent/CS228933B2/cs unknown
- 1982-06-02 ZA ZA823856A patent/ZA823856B/xx unknown
- 1982-06-03 ES ES512830A patent/ES512830A0/es active Granted
- 1982-06-03 CA CA000404443A patent/CA1190942A/en not_active Expired
- 1982-06-03 KR KR1019820002483A patent/KR840000473A/ko not_active Withdrawn
- 1982-06-04 NZ NZ200858A patent/NZ200858A/en unknown
- 1982-06-04 HU HU821820A patent/HU186522B/hu unknown
- 1982-06-04 NO NO821874A patent/NO153053C/no unknown
- 1982-06-04 SU SU823450433A patent/SU1114333A3/ru active
- 1982-06-04 PT PT75018A patent/PT75018B/pt unknown
- 1982-06-04 DD DD82240469A patent/DD207707A5/de unknown
- 1982-06-04 YU YU01202/82A patent/YU120282A/xx unknown
- 1982-06-04 AR AR289596A patent/AR230425A1/es active
- 1982-06-04 DK DK252482A patent/DK252482A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT75018A (fr) | 1982-07-01 |
| IL65866A (en) | 1985-11-29 |
| EP0067106A1 (fr) | 1982-12-15 |
| FR2507181A1 (fr) | 1982-12-10 |
| ZA823856B (en) | 1983-03-30 |
| FI821964A7 (fi) | 1982-12-06 |
| AR230425A1 (es) | 1984-04-30 |
| GR79490B (es) | 1984-10-30 |
| CS228933B2 (en) | 1984-05-14 |
| EP0067106B1 (fr) | 1985-04-10 |
| NO821874L (no) | 1982-12-06 |
| IE53276B1 (en) | 1988-09-28 |
| HU186522B (en) | 1985-08-28 |
| DK252482A (da) | 1982-12-06 |
| KR840000473A (ko) | 1984-02-22 |
| DD207707A5 (de) | 1984-03-14 |
| FI821964A0 (fi) | 1982-06-02 |
| ATE12631T1 (de) | 1985-04-15 |
| JPS5849344A (ja) | 1983-03-23 |
| YU120282A (en) | 1985-04-30 |
| NO153053B (no) | 1985-09-30 |
| US4435426A (en) | 1984-03-06 |
| ES512830A0 (es) | 1983-04-01 |
| CA1190942A (en) | 1985-07-23 |
| IL65866A0 (en) | 1982-08-31 |
| NO153053C (no) | 1986-01-08 |
| SU1114333A3 (ru) | 1984-09-15 |
| IE821226L (en) | 1982-12-05 |
| FR2507181B1 (es) | 1983-12-02 |
| PT75018B (fr) | 1984-01-04 |
| NZ200858A (en) | 1985-10-11 |
| DE3262965D1 (en) | 1985-05-15 |
| AU8410082A (en) | 1982-12-09 |
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