ES8306375A1 - "un procedimiento para la preparacion de imidazoquinazolinas". - Google Patents

"un procedimiento para la preparacion de imidazoquinazolinas".

Info

Publication number
ES8306375A1
ES8306375A1 ES515295A ES515295A ES8306375A1 ES 8306375 A1 ES8306375 A1 ES 8306375A1 ES 515295 A ES515295 A ES 515295A ES 515295 A ES515295 A ES 515295A ES 8306375 A1 ES8306375 A1 ES 8306375A1
Authority
ES
Spain
Prior art keywords
preparation
medicaments containing
imidazoquinazoline
mean hydrogen
imidazoquinazoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515295A
Other languages
English (en)
Other versions
ES515295A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8306375A1 publication Critical patent/ES8306375A1/es
Publication of ES515295A0 publication Critical patent/ES515295A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/58—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE IMIDAZOQUINAZOLINAS, DE FORMULA GENERAL (I), EN LA QUE R Y R SIGNIFICAN HIDROGENO, CLORO O BROMO; Y R Y R SIGNIFICAN HIDROGENO O METILO, Y SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), EN LA QUE R , R , R Y R TIENEN EL SIGNIFICADO YA INDICADO; Y R SIGNIFICA UN GRUPO BENCILO OPCIONALMENTE SUSTITUIDO EN EL ANILLO EN LA POSICION ORTO O PARA, POR UN ALQUILO O UN ALCOXILO, CON UN ACIDO. DE APLICACION EN EL CONTROL Y EN LA PREVENCION DE ENFERMEDADES, TALES COMO LA TROMBOSIS.
ES515295A 1981-08-28 1982-08-27 "un procedimiento para la preparacion de imidazoquinazolinas". Granted ES515295A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH554881 1981-08-28
CH374482 1982-06-17

Publications (2)

Publication Number Publication Date
ES8306375A1 true ES8306375A1 (es) 1983-06-01
ES515295A0 ES515295A0 (es) 1983-06-01

Family

ID=25693751

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515295A Granted ES515295A0 (es) 1981-08-28 1982-08-27 "un procedimiento para la preparacion de imidazoquinazolinas".

Country Status (14)

Country Link
US (1) US4455311A (es)
EP (1) EP0073060A1 (es)
AR (1) AR242389A1 (es)
AU (1) AU8752482A (es)
DK (1) DK349682A (es)
ES (1) ES515295A0 (es)
FI (1) FI822785L (es)
HU (1) HU185109B (es)
IL (1) IL66618A0 (es)
MC (1) MC1478A1 (es)
NO (1) NO822918L (es)
NZ (1) NZ201659A (es)
PH (1) PH19683A (es)
PT (1) PT75472A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS604186A (ja) * 1983-06-21 1985-01-10 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン化合物
JPS6028979A (ja) * 1983-07-14 1985-02-14 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン類化合物
US6416649B1 (en) 1997-06-26 2002-07-09 Alcoa Inc. Electrolytic production of high purity aluminum using ceramic inert anodes
PA8539501A1 (es) * 2001-02-14 2002-09-30 Warner Lambert Co Compuestos triazolo como inhibidores de mmp
AP2103A (en) * 2003-01-23 2010-02-08 Shire Holdings Ag A skin permeable form of an anagrelide and device therefore
US7700608B2 (en) 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
US20060030574A1 (en) * 2004-08-04 2006-02-09 Shire Holdings Ag Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors
US8426429B2 (en) * 2004-08-06 2013-04-23 Jansssen Pharmaceutica N.V. 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE)
US8383637B2 (en) * 2004-08-06 2013-02-26 Jansssen Pharmaceutica N.V. 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE)
US8436006B2 (en) * 2004-08-06 2013-05-07 Jansssen Pharmaceutica N.V. 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE)
EP1917245A1 (de) * 2005-08-21 2008-05-07 Abbott GmbH & Co. KG Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
WO2014089904A1 (en) 2012-12-10 2014-06-19 Abbvie Inc. Triazinone compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807507A (nl) * 1977-07-25 1979-01-29 Hoffmann La Roche Tricyclische verbindingen.
JPS5629591A (en) * 1979-08-17 1981-03-24 Dai Ichi Seiyaku Co Ltd Tricyclic compound
ZW16481A1 (en) * 1980-08-15 1982-03-10 Hoffmann La Roche Novel imidazoquinazoline derivatives

Also Published As

Publication number Publication date
EP0073060A1 (de) 1983-03-02
FI822785A0 (fi) 1982-08-10
PT75472A (en) 1982-09-01
PH19683A (en) 1986-06-13
IL66618A0 (en) 1982-12-31
DK349682A (da) 1983-03-01
NZ201659A (en) 1984-07-31
US4455311A (en) 1984-06-19
MC1478A1 (fr) 1983-06-17
HU185109B (en) 1984-12-28
ES515295A0 (es) 1983-06-01
AU8752482A (en) 1983-03-03
NO822918L (no) 1983-03-01
AR242389A1 (es) 1993-03-31
FI822785A7 (fi) 1983-03-01
FI822785L (fi) 1983-03-01

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