ES8308872A1 - Un procedimiento para la mejoracion de 3-(pirid-3-0,4-ilalquil)indoles - Google Patents

Un procedimiento para la mejoracion de 3-(pirid-3-0,4-ilalquil)indoles

Info

Publication number
ES8308872A1
ES8308872A1 ES507960A ES507960A ES8308872A1 ES 8308872 A1 ES8308872 A1 ES 8308872A1 ES 507960 A ES507960 A ES 507960A ES 507960 A ES507960 A ES 507960A ES 8308872 A1 ES8308872 A1 ES 8308872A1
Authority
ES
Spain
Prior art keywords
alkyl
pirid
indoles
procedure
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507960A
Other languages
English (en)
Spanish (es)
Other versions
ES507960A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Publication of ES507960A0 publication Critical patent/ES507960A0/es
Publication of ES8308872A1 publication Critical patent/ES8308872A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
ES507960A 1980-12-15 1981-12-14 Un procedimiento para la mejoracion de 3-(pirid-3-0,4-ilalquil)indoles Expired ES8308872A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8040081 1980-12-15

Publications (2)

Publication Number Publication Date
ES507960A0 ES507960A0 (es) 1983-10-01
ES8308872A1 true ES8308872A1 (es) 1983-10-01

Family

ID=10517993

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507960A Expired ES8308872A1 (es) 1980-12-15 1981-12-14 Un procedimiento para la mejoracion de 3-(pirid-3-0,4-ilalquil)indoles

Country Status (22)

Country Link
US (1) US4363912A (cs)
EP (1) EP0054417B1 (cs)
JP (1) JPS57181082A (cs)
KR (1) KR830007552A (cs)
AR (1) AR229110A1 (cs)
AU (1) AU525296B2 (cs)
CA (1) CA1143737A (cs)
CS (1) CS228527B2 (cs)
DD (1) DD202290A5 (cs)
DE (1) DE3167879D1 (cs)
DK (1) DK552581A (cs)
ES (1) ES8308872A1 (cs)
FI (1) FI814003L (cs)
GR (1) GR76355B (cs)
IE (1) IE51949B1 (cs)
IL (1) IL64534A0 (cs)
NO (1) NO814264L (cs)
PH (1) PH17576A (cs)
PL (1) PL133634B1 (cs)
PT (1) PT74123B (cs)
YU (1) YU293481A (cs)
ZA (1) ZA818665B (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
GB8609175D0 (en) * 1986-04-15 1986-05-21 Ici America Inc Heterocyclic carboxamides
US6214991B1 (en) * 1998-03-31 2001-04-10 The Institute For Pharmaceutical Discovery, Inc. Substituted indolealkanoic acids
TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
WO2001051489A2 (en) * 2000-01-14 2001-07-19 The Institutes For Pharmaceutical Discovery, Llc Methods for lowering uric acid levels
CA2509170A1 (en) * 2002-12-10 2004-06-24 Wyeth Substituted 3-alkyl and 3-arylalkyl 1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
GB0324763D0 (en) * 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
CA2658496A1 (en) 2006-07-22 2008-01-31 Oxagen Limited 2-{5-fluoro-2-methyl-3-[2-(phenylsulfonyl)benzyl]-1h-indol-yl} acetic acid derivatives and esters thereof having crth2 antagonist activity
BRPI0817397A2 (pt) * 2007-09-24 2015-04-07 Allergan Inc Compostos indol contendo grupos arila ou heteroarila com atividade biológica do receptor de esfingosina-1-fosfato (sip)
US7750027B2 (en) * 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
CA2712017C (en) * 2008-01-18 2016-08-09 Oxagen Limited Compounds having crth2 antagonist activity
EP2265581A1 (en) * 2008-01-22 2010-12-29 Oxagen Limited Compounds having crth2 antagonist activity
JP2011509991A (ja) * 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5173M (cs) * 1966-02-11 1967-06-19
FR7337M (cs) * 1968-01-11 1969-10-13
GB2045244B (en) 1979-03-07 1983-01-26 Pfizer Ltd 3-1-(imidazolylalkyl) indoles
US4322533A (en) * 1980-03-17 1982-03-30 Lesher George Y 1H-Indole-2,3-dione derivatives

Also Published As

Publication number Publication date
PT74123B (en) 1983-12-19
ES507960A0 (es) 1983-10-01
DK552581A (da) 1982-06-16
CS228527B2 (en) 1984-05-14
DD202290A5 (de) 1983-09-07
NO814264L (no) 1982-06-16
EP0054417B1 (en) 1984-12-19
PL234253A1 (en) 1983-05-23
ZA818665B (en) 1982-10-27
PT74123A (en) 1982-01-01
IL64534A0 (en) 1982-03-31
EP0054417A1 (en) 1982-06-23
DE3167879D1 (en) 1985-01-31
FI814003A7 (fi) 1982-06-16
IE51949B1 (en) 1987-04-29
KR830007552A (ko) 1983-10-21
US4363912A (en) 1982-12-14
YU293481A (en) 1984-10-31
CA1143737A (en) 1983-03-29
IE812928L (en) 1982-06-15
AR229110A1 (es) 1983-06-15
FI814003L (fi) 1982-06-16
GR76355B (cs) 1984-08-06
PL133634B1 (en) 1985-06-29
PH17576A (en) 1984-10-01
AU7848881A (en) 1982-06-24
JPS57181082A (en) 1982-11-08
AU525296B2 (en) 1982-10-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980203