ES8308880A1 - 10-(1-aza-(2,2,2)-biciclo-3-octil) 10 h-fenotiazin-2-sulfonamidas. - Google Patents

10-(1-aza-(2,2,2)-biciclo-3-octil) 10 h-fenotiazin-2-sulfonamidas.

Info

Publication number
ES8308880A1
ES8308880A1 ES513883A ES513883A ES8308880A1 ES 8308880 A1 ES8308880 A1 ES 8308880A1 ES 513883 A ES513883 A ES 513883A ES 513883 A ES513883 A ES 513883A ES 8308880 A1 ES8308880 A1 ES 8308880A1
Authority
ES
Spain
Prior art keywords
aza
reaction
sulfonamidas
fenotiazin
biciclo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513883A
Other languages
English (en)
Other versions
ES513883A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmindustrie
Original Assignee
Pharmindustrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmindustrie filed Critical Pharmindustrie
Publication of ES8308880A1 publication Critical patent/ES8308880A1/es
Publication of ES513883A0 publication Critical patent/ES513883A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE 10- 1-AZA-(2,2,2)-BICICLO-3-OCTIL -10H-FENOTIAZIN-2-SULFONAMIDAS. SE EFECTUAN LAS SIGUIENTES ETAPAS: 1 ) REACCION DE LA N,N-DIMETIL 10- 1-AZA-(2,2,2)-BICICLO-3-OCTIL -10H-FENOTIAZIN-2- -SULFONAMIDA CON UN ALCOHOLATO DE METAL ALCALINO EN UN DISOLVENTE. 2 ) REACCION DEL SULFINATO OBTENIDO MEDIANTE UN OXIDANTE EN MEDIO ACIDO ACUOSO; SE ALCANIZA POR MEDIO DE UN HIDROXIDO DE METAL ALCALINO Y SE SOMETE LA SAL DE ACIDO OBTENIDA A LA ACCION DEL CLORURO DE TIONILO. 3 ) REACCION DE LA MEZCLA COMPRENDIENDO EL CLORURO DE SULFONILO CON R-NH<2. SE OBTIENEN COMPUESTOS (I), EN QUE R ES HIDROGENO O UN GRUPO ALQUILO.
ES513883A 1981-07-10 1982-07-09 10-(1-aza-(2,2,2)-biciclo-3-octil) 10 h-fenotiazin-2-sulfonamidas. Granted ES513883A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8113602A FR2509307A1 (fr) 1981-07-10 1981-07-10 (aza-1 bicyclo-(2,2,2) octyl-3)-10 10h phenothiazine-sulfonamide-2, ses derives, procede pour leur preparation et leur utilisation comme medicaments

Publications (2)

Publication Number Publication Date
ES8308880A1 true ES8308880A1 (es) 1983-10-01
ES513883A0 ES513883A0 (es) 1983-10-01

Family

ID=9260427

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513883A Granted ES513883A0 (es) 1981-07-10 1982-07-09 10-(1-aza-(2,2,2)-biciclo-3-octil) 10 h-fenotiazin-2-sulfonamidas.

Country Status (14)

Country Link
US (1) US4451461A (es)
EP (1) EP0070753A1 (es)
JP (1) JPS5818382A (es)
AU (1) AU8578282A (es)
DK (1) DK308582A (es)
ES (1) ES513883A0 (es)
FI (1) FI822455L (es)
FR (1) FR2509307A1 (es)
GR (1) GR69437B (es)
IL (1) IL65994A0 (es)
MA (1) MA19527A1 (es)
NO (1) NO822395L (es)
PT (1) PT75162B (es)
ZA (1) ZA824873B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413915D0 (en) * 1984-05-31 1984-07-04 Wellcome Found Phenothiazine compounds
US5506247A (en) * 1988-04-15 1996-04-09 T Cell Sciences, Inc. Compounds that inhibit complement and/or suppress immune activity
US5191078A (en) * 1989-12-21 1993-03-02 Zambon Group S.P.A. Process for the direct and regioselective functionalization in position 2 of phenothiazine
IT1237209B (it) * 1989-12-21 1993-05-27 Zambon Spa Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina
US6834636B2 (en) 1999-03-23 2004-12-28 Thomas Engine Company Single-ended barrel engine with double-ended, double roller pistons
JP4720518B2 (ja) * 2006-01-20 2011-07-13 株式会社ケンウッド 電子機器の筐体構造

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987042A (en) * 1969-03-03 1976-10-19 Claude Gueremy Phenothiazine derivative
GB1250534A (es) * 1969-03-03 1971-10-20
FR2318638A2 (fr) * 1975-07-25 1977-02-18 Sogeras Nouveaux derives de la phenothiazine et procede pour leur preparation

Also Published As

Publication number Publication date
FI822455A7 (fi) 1983-01-11
NO822395L (no) 1983-01-11
PT75162B (fr) 1984-02-21
ZA824873B (en) 1983-04-27
PT75162A (fr) 1982-07-01
FR2509307A1 (fr) 1983-01-14
US4451461A (en) 1984-05-29
JPS5818382A (ja) 1983-02-02
DK308582A (da) 1983-01-11
GR69437B (es) 1982-06-18
ES513883A0 (es) 1983-10-01
FI822455A0 (fi) 1982-07-09
EP0070753A1 (fr) 1983-01-26
AU8578282A (en) 1983-01-13
IL65994A0 (en) 1982-09-30
FI822455L (fi) 1983-01-11
FR2509307B1 (es) 1984-03-30
MA19527A1 (fr) 1983-04-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202