ES8400742A1 - Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co. - Google Patents

Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co.

Info

Publication number
ES8400742A1
ES8400742A1 ES519463A ES519463A ES8400742A1 ES 8400742 A1 ES8400742 A1 ES 8400742A1 ES 519463 A ES519463 A ES 519463A ES 519463 A ES519463 A ES 519463A ES 8400742 A1 ES8400742 A1 ES 8400742A1
Authority
ES
Spain
Prior art keywords
medicaments
processes
preparation
methods
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519463A
Other languages
English (en)
Other versions
ES519463A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of ES519463A0 publication Critical patent/ES519463A0/es
Publication of ES8400742A1 publication Critical patent/ES8400742A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE LAS DIBENZOOXEPINAS SUSTITUIDAS Y DE SUS SALES DE ADICION CON UN ACIDO MINERAL U ORGANICO.SE SAPONIFICA UN COMPUESTO METILIDIENICO DE FORMULA (II) DONDE R Y RK SON IDENTICOS O DIFERENTES Y REPRESENTAN HIDROGENO, ALCOHILO INFERIOR, ALCOXI INFERIOR, TRIFLUOROMETILO O UN GRUPO ALCOHILTIO, A. ES OXIGENO O AZUFRE Y M Y M IGUALES O DIFERENTES, REPRESENTAN UN NUMERO ENTERO DE 1 O 2, EN MEDIO ALCALINO PARA FORMAR UN DERIVADO AMINADO DE FORMULA (IV) EN DONDE R1 Y R2 SON IGUALES O DIFERENTES Y REPRESENTAN HIDROGENO, ALCOHILO INFERIOR, ARALCOHILO INFERIOR O UN HIDROXI ALCOHILOINFERIOR, EN PRESENCIA DE UN AGENTE DE FUNCIONALIZACION DEL CARBOXILO PARA FORMAR LA AMIDA METILIDENICA DE FORMULA (V) QUE SE PUEDE REDUCIR O HIDROGENAR EN UN DERIVADO ETILAMINADO DE FORMULA GENERAL (I).SE UTILIZAN COMO AGENTES ANTIDEPRESORES, ANXIOLITICOS Y SEDANTES.
ES519463A 1980-04-10 1983-02-01 Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co. Expired ES8400742A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8008023A FR2480283A1 (fr) 1980-04-10 1980-04-10 Nouveaux derives tricycliques, leurs procedes de preparation et leur utilisation comme medicament

Publications (2)

Publication Number Publication Date
ES519463A0 ES519463A0 (es) 1983-11-16
ES8400742A1 true ES8400742A1 (es) 1983-11-16

Family

ID=9240699

Family Applications (2)

Application Number Title Priority Date Filing Date
ES500942A Expired ES8306483A1 (es) 1980-04-10 1981-03-31 Procedimiento de preparacion de las dibezooxepinas sustituidas y de sus sales de adicion con un acido mineral u organico
ES519463A Expired ES8400742A1 (es) 1980-04-10 1983-02-01 Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES500942A Expired ES8306483A1 (es) 1980-04-10 1981-03-31 Procedimiento de preparacion de las dibezooxepinas sustituidas y de sus sales de adicion con un acido mineral u organico

Country Status (23)

Country Link
US (1) US4459306A (es)
EP (1) EP0041410B1 (es)
JP (1) JPS56158780A (es)
AR (1) AR229026A1 (es)
AT (1) ATE5257T1 (es)
AU (1) AU538054B2 (es)
CA (1) CA1181068A (es)
DD (1) DD158242A5 (es)
DE (1) DE3161358D1 (es)
DK (1) DK159981A (es)
ES (2) ES8306483A1 (es)
FI (1) FI811059A7 (es)
FR (1) FR2480283A1 (es)
GR (1) GR75194B (es)
IL (1) IL62622A (es)
MA (1) MA19113A1 (es)
NO (1) NO811229L (es)
NZ (1) NZ196774A (es)
OA (1) OA06779A (es)
PT (1) PT72833B (es)
SU (1) SU1106444A3 (es)
YU (1) YU92481A (es)
ZA (1) ZA812379B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2094790B (en) * 1981-03-13 1985-10-09 Spofa Vereinigte Pharma Werke Tricycle compounds
ATE35262T1 (de) * 1982-09-30 1988-07-15 Merck Frosst Canada Inc 6h-dibenz(b,e)(1,4)oxathiepin-derivate und deren herstellung.
CN1079670C (zh) * 1994-03-02 2002-02-27 阿克佐诺贝尔公司 舌下或颊给药的药物组合物
JP4006796B2 (ja) 1997-11-17 2007-11-14 株式会社日立製作所 個人情報管理方法および装置
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US6683072B1 (en) 2003-02-04 2004-01-27 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of irritable bowel syndrome and nonulcer dyspepsia
US20050227961A1 (en) * 2004-04-08 2005-10-13 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN111377901A (zh) * 2018-12-27 2020-07-07 华东理工大学 一种缩酚酸环醚类化合物及其制备方法与用途
CA3215043A1 (en) * 2021-04-10 2022-10-13 Kevin Julian Hodgetts Taar1 and serotonin modulators, and pharmaceutical compositions, and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1312891A (fr) * 1962-01-29 1962-12-21 Geigy Ag J R Nouveaux 1.5-benzo-dioxépannes et leur préparation
BE613210A (fr) * 1961-01-30 1962-07-30 Geigy Ag J R Nouveaux benzo-dioxépannes et leur préparation
FR1312889A (fr) * 1962-01-29 1962-12-21 Geigy Ag J R Nouveaux benzo-dioxépannes et leur préparation
US3758528A (en) * 1970-03-13 1973-09-11 Science Union & Cie Tricyclic compounds
US3821249A (en) * 1970-03-13 1974-06-28 En Nom Collectif Science Union Dibenzothiazefin derivatives
US4039676A (en) * 1975-06-23 1977-08-02 Ciba-Geigy Corporation 2-piperidinoalkyl-1,4-benzodioxans
US4335122A (en) * 1981-03-18 1982-06-15 Hoechst-Roussel Pharmaceuticals Inc. Dihydro-dibenzoxepines-thiepines and -morphanthridones, compositions and use

Also Published As

Publication number Publication date
GR75194B (es) 1984-07-13
FI811059L (fi) 1981-10-11
OA06779A (fr) 1982-12-31
ES519463A0 (es) 1983-11-16
IL62622A0 (en) 1981-06-29
JPS6116394B2 (es) 1986-04-30
ES500942A0 (es) 1983-06-01
FI811059A7 (fi) 1981-10-11
AR229026A1 (es) 1983-05-31
ATE5257T1 (de) 1983-11-15
DK159981A (da) 1981-10-11
NO811229L (no) 1981-10-12
PT72833A (fr) 1981-05-01
ES8306483A1 (es) 1983-06-01
FR2480283B1 (es) 1983-09-23
ZA812379B (en) 1982-04-28
EP0041410B1 (fr) 1983-11-09
AU538054B2 (en) 1984-07-26
CA1181068A (fr) 1985-01-15
SU1106444A3 (ru) 1984-07-30
US4459306A (en) 1984-07-10
NZ196774A (en) 1983-09-30
JPS56158780A (en) 1981-12-07
AU6934081A (en) 1981-10-15
PT72833B (fr) 1982-07-26
FR2480283A1 (fr) 1981-10-16
MA19113A1 (fr) 1981-12-31
DD158242A5 (de) 1983-01-05
DE3161358D1 (en) 1983-12-15
YU92481A (en) 1984-02-29
IL62622A (en) 1984-10-31
EP0041410A1 (fr) 1981-12-09

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