ES8405366A1 - Process for the preparation of 2-/E-/-phenylmethylenecycloheptan-1- one-/E/-oxime - Google Patents

Process for the preparation of 2-/E-/-phenylmethylenecycloheptan-1- one-/E/-oxime

Info

Publication number
ES8405366A1
ES8405366A1 ES521096A ES521096A ES8405366A1 ES 8405366 A1 ES8405366 A1 ES 8405366A1 ES 521096 A ES521096 A ES 521096A ES 521096 A ES521096 A ES 521096A ES 8405366 A1 ES8405366 A1 ES 8405366A1
Authority
ES
Spain
Prior art keywords
phenylmethylenecycloheptan
formula
oxime
preparation
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521096A
Other languages
Spanish (es)
Other versions
ES521096A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES521096A0 publication Critical patent/ES521096A0/en
Publication of ES8405366A1 publication Critical patent/ES8405366A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the preparation of 2-/E/-phenylmethylenecycloheptan-1- one-/E/-oxime of the formula /I/ < IMAGE > free of other isomers comprises reacting 2-/E/-phenylmethylenecycloheptan- 1-one of the formula /II/ < IMAGE > with hydroxylamine obtained "in situ" from a hydroxylamine salt in the presence of a base. The reaction is carried out in water and/or in a lower, with water unrestrictedly miscible, aliphatic alcohol, and subsequently the alcohol content of the reaction medium is adjusted to 40-60%. The compound of the formula /I/ is isolated from the reaction mixture by known methods. The 2-/E/-phenylmethylenecycloheptan- 1-one-/E/-oxime of the formula /I/serves as intermediate for the synthesis of compounds possessing valuable pharmaceutical properties.
ES521096A 1982-04-01 1983-03-29 Process for the preparation of 2-/E-/-phenylmethylenecycloheptan-1- one-/E/-oxime Expired ES8405366A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU82997A HU185518B (en) 1982-04-01 1982-04-01 Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime

Publications (2)

Publication Number Publication Date
ES521096A0 ES521096A0 (en) 1984-06-01
ES8405366A1 true ES8405366A1 (en) 1984-06-01

Family

ID=10952372

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521096A Expired ES8405366A1 (en) 1982-04-01 1983-03-29 Process for the preparation of 2-/E-/-phenylmethylenecycloheptan-1- one-/E/-oxime

Country Status (18)

Country Link
JP (1) JPS58208262A (en)
AT (1) AT384423B (en)
BE (1) BE896279A (en)
CA (1) CA1210027A (en)
CH (1) CH656121B (en)
DD (1) DD209619A5 (en)
DE (1) DE3311895A1 (en)
DK (1) DK148783A (en)
ES (1) ES8405366A1 (en)
FI (1) FI831087A7 (en)
FR (1) FR2524464B1 (en)
GB (1) GB2117773B (en)
HU (1) HU185518B (en)
IL (1) IL68079A (en)
IT (1) IT1194184B (en)
NL (1) NL8301175A (en)
SE (1) SE8301817L (en)
YU (1) YU77683A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2279757C2 (en) * 2004-09-13 2006-07-10 "Центр Разработки Нефтедобывающего Оборудования" ("Црно") Method for controlling gated electric motor and device for realization of said method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4083978A (en) * 1976-01-27 1978-04-11 Egyt Gyogyszervegyeszeti Gyar Oxime ethers

Also Published As

Publication number Publication date
FI831087L (en) 1983-10-02
IL68079A0 (en) 1983-06-15
GB2117773B (en) 1985-08-29
GB8308956D0 (en) 1983-05-11
ES521096A0 (en) 1984-06-01
IL68079A (en) 1986-10-31
CH656121B (en) 1986-06-13
NL8301175A (en) 1983-11-01
HU185518B (en) 1985-02-28
IT1194184B (en) 1988-09-14
SE8301817D0 (en) 1983-03-30
IT8320428A0 (en) 1983-04-01
DD209619A5 (en) 1984-05-16
DE3311895A1 (en) 1983-10-06
JPS58208262A (en) 1983-12-03
FI831087A7 (en) 1983-10-02
CA1210027A (en) 1986-08-19
BE896279A (en) 1983-09-28
DK148783A (en) 1983-10-02
IT8320428A1 (en) 1984-10-01
FR2524464B1 (en) 1986-05-30
YU77683A (en) 1985-12-31
SE8301817L (en) 1983-10-02
ATA116983A (en) 1987-04-15
DK148783D0 (en) 1983-03-30
GB2117773A (en) 1983-10-19
AT384423B (en) 1987-11-10
FR2524464A1 (en) 1983-10-07
FI831087A0 (en) 1983-03-30

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