ES8406452A1 - Procedimiento para la obtencion de nuevos derivados de benzazol. - Google Patents

Procedimiento para la obtencion de nuevos derivados de benzazol.

Info

Publication number
ES8406452A1
ES8406452A1 ES513169A ES513169A ES8406452A1 ES 8406452 A1 ES8406452 A1 ES 8406452A1 ES 513169 A ES513169 A ES 513169A ES 513169 A ES513169 A ES 513169A ES 8406452 A1 ES8406452 A1 ES 8406452A1
Authority
ES
Spain
Prior art keywords
optionally
formula
group
derivatives
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513169A
Other languages
English (en)
Other versions
ES513169A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8406452A1 publication Critical patent/ES8406452A1/es
Publication of ES513169A0 publication Critical patent/ES513169A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE NUEVOS DERIVADOS DE BENZAZOL.CONSISTE EN TRANSFORMAR POR SOLVOLISIS EL RADICAL Y5 DEL COMPUESTO DE FORMULA (II), EN UN GRUPO DE FORMULA R1-C(FX1)-, PARA OBTENER EL COMPUESTO DE FORMULA (I), DONDE R ES UN GRUPO PIPERAZINE, O UN GRUPO DE FORMULA R2-ALK-X2; R2 ES CARBOXI, HIDROXIMETILO; ALK ES ALQUILENO INFERIOR O ALQUILIDENO INFERIOR; X1 Y X2 SON OXIGENO O AZUFRE; PH ES 1,2-FENILENO; X3 ES OXIGENO, AZUFRE O IMINO; Y R3 ES ALQUILO INFERIOR O CICLOALQUILO.TIENE APLICACIONES POR SUS EFECTOS ANTIPARASITARIOS, ESPECIALMENTE CONTRA LOS HELMINTOS PARASITARIOS.
ES513169A 1980-05-22 1982-06-16 Procedimiento para la obtencion de nuevos derivados de benzazol. Granted ES513169A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH401680 1980-05-22

Publications (2)

Publication Number Publication Date
ES8406452A1 true ES8406452A1 (es) 1984-07-01
ES513169A0 ES513169A0 (es) 1984-07-01

Family

ID=4268232

Family Applications (3)

Application Number Title Priority Date Filing Date
ES502355A Granted ES502355A0 (es) 1980-05-22 1981-05-20 Procedimiento para la obtencion de nuevos derivados del ben-zazol
ES513169A Granted ES513169A0 (es) 1980-05-22 1982-06-16 Procedimiento para la obtencion de nuevos derivados de benzazol.
ES513170A Expired ES8308316A1 (es) 1980-05-22 1982-06-16 Procedimiento para la obtencion de nuevos derivados del benzazol.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES502355A Granted ES502355A0 (es) 1980-05-22 1981-05-20 Procedimiento para la obtencion de nuevos derivados del ben-zazol

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES513170A Expired ES8308316A1 (es) 1980-05-22 1982-06-16 Procedimiento para la obtencion de nuevos derivados del benzazol.

Country Status (28)

Country Link
US (1) US4511567A (es)
EP (1) EP0041046B1 (es)
JP (1) JPS5718670A (es)
KR (1) KR850000555B1 (es)
AU (1) AU547922B2 (es)
CY (1) CY1339A (es)
DD (1) DD159073A5 (es)
DE (1) DE3176402D1 (es)
DK (1) DK164786C (es)
ES (3) ES502355A0 (es)
FI (1) FI75564C (es)
GB (1) GB2076399B (es)
GR (1) GR75253B (es)
HK (1) HK74686A (es)
HU (1) HU186770B (es)
IE (1) IE52426B1 (es)
IL (1) IL62928A (es)
IN (1) IN153293B (es)
KE (1) KE3645A (es)
MA (1) MA19290A1 (es)
MW (1) MW2181A1 (es)
MY (1) MY8700141A (es)
OA (1) OA06816A (es)
PH (1) PH16754A (es)
PT (1) PT73066B (es)
ZA (1) ZA8103409D (es)
ZM (1) ZM4481A1 (es)
ZW (1) ZW11981A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8423697D0 (en) * 1984-09-19 1984-10-24 Ciba Geigy Ag Benzazole derivatives
US5246927A (en) * 1988-08-17 1993-09-21 Ciba-Geigy Corporation Benzazole derivatives, processes for their preparation containing such compounds and the use thereof
ES2145743T3 (es) * 1990-12-28 2000-07-16 Teijin Ltd Compuesto de anillo condensado benzoxa, su produccion y composicion farmaceutica que lo contiene.
AU2962397A (en) * 1996-06-07 1998-01-07 Novartis Ag Benzazole derivatives
US6177572B1 (en) * 1997-08-20 2001-01-23 Sepracor, Inc. Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use
EP3235815A1 (de) * 2016-04-19 2017-10-25 Philipps-Universität Marburg Wirkstoffe gegen parasitäre helminthen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1087561A (en) * 1963-02-16 1967-10-18 Fisons Pest Control Ltd Fluorinated benzimidazoles and compositions containing them
IE31812B1 (en) * 1967-02-03 1973-01-10 Merck & Co Inc Benzimidazole derivatives
US3646049A (en) * 1970-03-05 1972-02-29 Merck & Co Inc Acylaminobenzimidazole derivatives
US3714180A (en) * 1970-08-12 1973-01-30 Squibb & Sons Inc Sulfonyl benzimidazoles
BE792402A (fr) * 1971-12-07 1973-06-07 Ciba Geigy Composes heterocycliques azotes et medicaments anthelminthiqueset antimicrobiens qui en contiennent

Also Published As

Publication number Publication date
IE52426B1 (en) 1987-10-28
OA06816A (fr) 1982-12-31
JPH0357099B2 (es) 1991-08-30
PT73066B (en) 1983-02-08
GR75253B (es) 1984-07-13
IN153293B (es) 1984-06-30
CY1339A (en) 1987-01-16
ES8300724A1 (es) 1982-11-01
ES502355A0 (es) 1982-11-01
ZW11981A1 (en) 1981-12-16
IE811127L (en) 1981-11-22
IL62928A (en) 1985-03-31
ZM4481A1 (en) 1982-01-21
ZA8103409D (en) 1982-06-30
DK224381A (da) 1981-11-23
HU186770B (en) 1985-09-30
GB2076399A (en) 1981-12-02
JPS5718670A (en) 1982-01-30
DK164786C (da) 1993-01-04
AU547922B2 (en) 1985-11-14
PT73066A (en) 1981-06-01
FI75564C (fi) 1988-07-11
KE3645A (en) 1986-07-11
IL62928A0 (en) 1981-07-31
MW2181A1 (en) 1982-10-13
FI75564B (fi) 1988-03-31
MY8700141A (en) 1987-12-31
EP0041046A1 (de) 1981-12-02
ES513170A0 (es) 1983-09-01
MA19290A1 (fr) 1982-04-01
ES513169A0 (es) 1984-07-01
EP0041046B1 (de) 1987-09-02
AU7091081A (en) 1981-11-26
KR850000555B1 (ko) 1985-04-26
DK164786B (da) 1992-08-17
PH16754A (en) 1984-02-15
GB2076399B (en) 1983-11-02
US4511567A (en) 1985-04-16
HK74686A (en) 1986-10-10
DE3176402D1 (en) 1987-10-08
KR830006231A (ko) 1983-09-20
DD159073A5 (de) 1983-02-16
FI811531L (fi) 1981-11-23
ES8308316A1 (es) 1983-09-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201