ES8501358A1 - Un procedimiento para la prepracion de eteres 2-aminoetilicos. - Google Patents

Un procedimiento para la prepracion de eteres 2-aminoetilicos.

Info

Publication number
ES8501358A1
ES8501358A1 ES524174A ES524174A ES8501358A1 ES 8501358 A1 ES8501358 A1 ES 8501358A1 ES 524174 A ES524174 A ES 524174A ES 524174 A ES524174 A ES 524174A ES 8501358 A1 ES8501358 A1 ES 8501358A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
nr4r5
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524174A
Other languages
English (en)
Other versions
ES524174A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8501358A1 publication Critical patent/ES8501358A1/es
Publication of ES524174A0 publication Critical patent/ES524174A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/303—Compounds having groups having acetal carbon atoms bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/313—Compounds having groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE ETERES 2-AMINOETILICOS DE FORMULA GENERAL (I) O SUS SALES, ESTERES O AMIDAS, FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN REDUCIR UN GRUPO OXO O UN DOBLE ENLACE O UN RESTO REDUCTIBLE A UN GRUPO X DE UN COMPUESTO DE FORMULA (II) O UN ESTER O AMIDA DEL MISMO.DE APLICACION EN FARMACIA POR SU ACTIVIDAD ANTIHIPERGLICEMICA, ANTI-OBESIDAD, ANTI-INFLAMATORIA Y COMO INHIBIDOR DE LA AGREGACION DE PLAQUETAS.
ES524174A 1982-07-16 1983-07-15 Un procedimiento para la prepracion de eteres 2-aminoetilicos. Granted ES524174A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8220645 1982-07-16
GB8228753 1982-10-07
GB8235672 1982-12-15

Publications (2)

Publication Number Publication Date
ES8501358A1 true ES8501358A1 (es) 1984-11-16
ES524174A0 ES524174A0 (es) 1984-11-16

Family

ID=27261665

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524174A Granted ES524174A0 (es) 1982-07-16 1983-07-15 Un procedimiento para la prepracion de eteres 2-aminoetilicos.

Country Status (7)

Country Link
US (1) US4629737A (es)
EP (1) EP0099707B1 (es)
AU (1) AU557743B2 (es)
CA (1) CA1253870A (es)
DE (1) DE3368258D1 (es)
ES (1) ES524174A0 (es)
NZ (1) NZ204901A (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3462789D1 (en) * 1983-08-17 1987-04-30 Beecham Group Plc 2-phenylethylamine derivatives
US5166218A (en) * 1983-10-19 1992-11-24 Hoffmann-La Roche Inc. Phenoxypropanolamines and pharmaceutical compositions thereof
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
DE3466387D1 (en) * 1983-11-04 1987-10-29 Beecham Group Plc Tertiary amines
JPS60158153A (ja) * 1984-01-12 1985-08-19 イーライ・リリー・アンド・カンパニー 変力剤
GB8415377D0 (en) * 1984-06-15 1984-07-18 Beecham Group Plc Compounds
GB8418472D0 (en) * 1984-07-19 1984-08-22 Beecham Group Plc Compounds
GB8420837D0 (en) * 1984-08-16 1984-09-19 Beecham Group Plc Compounds
CA1287061C (en) * 1986-06-27 1991-07-30 F. Hoffmann-La Roche Ag Pyridine ethanolamine derivatives
EP0300290B1 (de) * 1987-07-21 1991-12-18 F. Hoffmann-La Roche Ag Phenoxypropanolamine
FR2662082B1 (fr) * 1990-05-15 1994-12-23 Immunotech Sa Nouveaux derives de mediateurs endogenes, leurs sels, procede de preparation et applications.
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
GB9124512D0 (en) * 1991-11-19 1992-01-08 Smithkline Beecham Plc Novel compounds
NO179246C (no) * 1991-11-20 1996-09-04 Sankyo Co Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav
EP0558824A1 (en) * 1992-02-04 1993-09-08 Duphar International Research B.V Method for the preparation of vicinal aminoalcohols and optically active O-protected derivatives thereof
US5321036A (en) * 1993-02-10 1994-06-14 Bristol-Myers Squibb Company Thiazole and oxazole-based β3 adrenergic receptor agonists
HUT69285A (en) * 1993-04-26 1995-09-28 Fujisawa Pharmaceutical Co Ethanolamine derivatives, pharmaceutical compns. contg. them and process to prepare the sald compds.
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5629200A (en) * 1993-11-18 1997-05-13 Daicel Chemical Industries, Ltd. Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
DE69711519T2 (de) 1996-09-05 2002-10-31 Eli Lilly And Co., Indianapolis Carbazolanaloge als selektive beta3-adrenergische Agonisten
US5808080A (en) * 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
CO5011072A1 (es) * 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
WO1999031045A1 (en) 1997-12-18 1999-06-24 Kissei Pharmaceutical Co., Ltd. Phenylaminoalkylcarboxylic acid derivatives and medicinal compositions containing the same
DE19943635A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1340457A (en) * 1971-02-26 1973-12-12 Smithkline Corp N-phenylisoalkyl-beta-alkoxy-beta-trifluoromethylphenal kylamines
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
DE3061205D1 (en) * 1979-06-16 1983-01-05 Beecham Group Plc Secondary amines, their preparation and use in pharmaceutical compositions
DE3061334D1 (en) * 1979-06-16 1983-01-20 Beecham Group Plc Ethanamine derivatives, their preparation and use in pharmaceutical compositions
ATE2265T1 (de) * 1979-10-25 1983-02-15 Beecham Group Plc Sekundaere amine, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
EP0040000B1 (en) * 1980-05-08 1983-10-12 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
DE3162756D1 (en) * 1980-05-22 1984-04-26 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
EP0052963B1 (en) * 1980-11-20 1985-02-20 Beecham Group Plc Secondary amines

Also Published As

Publication number Publication date
ES524174A0 (es) 1984-11-16
EP0099707A1 (en) 1984-02-01
DE3368258D1 (en) 1987-01-22
CA1253870A (en) 1989-05-09
AU557743B2 (en) 1987-01-08
US4629737A (en) 1986-12-16
EP0099707B1 (en) 1986-12-10
AU1682683A (en) 1984-02-23
NZ204901A (en) 1987-03-06

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